SCHEMBL43924

SCHEMBL43924

O=C1c2ccc3c(c2)C(=O)N(O)C(=O)c2cc1ccc2C(=O)N(O)C3=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.48
ERCC1 P07992 2/20 0.41
FEN1 P39748 2/20 0.41
ERCC4 Q92889 2/20 0.41
POLB P06746 4/20 0.38
MAPT P10636 3/20 0.38
CYP1A2 P05177 1/20 0.38
TSHR P16473 1/20 0.38
ALOX12 P18054 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ESR1 P03372 4/20 0.37
ESR2 Q92731 2/20 0.37
KMT2A Q03164 4/20 0.35
LMNA P02545 2/20 0.35
XBP1 P17861 2/20 0.35
HTT P42858 2/20 0.35
MEN1 O00255 2/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
APAF1 O14727 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25060901 0.91 KDM4E (0.57) KDM4EERCC1FEN1ERCC4POLB
SCHEMBL7900508 0.76 ESR1 (0.62) ESR1ESR2KMT2AMEN1CA1
SCHEMBL2239437 0.74 S100A4 (0.52) ERCC1FEN1ERCC4POLBMAPT
SCHEMBL42876 0.74 ALDH1A1 (0.55) KDM4EERCC1FEN1ERCC4POLB
SCHEMBL6651899 0.74 ESR1 (0.59) ERCC1FEN1ERCC4POLBESR1
SCHEMBL3279383 0.74 CA9 (0.53) POLBTSHRNPC1RAB9AALDH1A1
SCHEMBL31411903 0.74 CA9 (0.53) POLBTSHRNPC1RAB9AALDH1A1
SCHEMBL25060903 0.74 HDAC1 (0.50) KDM4EPOLBKMT2AMEN1
SCHEMBL3681961 0.74 ALDH1A1 (0.43) KDM4EERCC1FEN1ERCC4POLB
SCHEMBL25037369 0.73 KDM4E (0.37) KDM4EERCC1FEN1ERCC4POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 426 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11213804-B2 Dehydrogenation catalysts and methods of making and using the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-01-04 US disclosed
EP-3327003-B1 PROCESS FOR CONCENTRATING A MIXTURE CONTAINING ORGANIC HYDROPEROXIDE EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-09-16 EP disclosed
EP-3180304-B1 PROCESS FOR PRODUCING CYCLOHEXANONE EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-10-30 EP disclosed
US-20190283002-A1 Dehydrogenation Catalysts and Methods of Making and Using the Same EXXONMOBIL CHEMICAL PATENTS INC. 2019-09-19 US disclosed
EP-3013779-B1 PROCESS FOR PRODUCING PHENOL AND/OR CYCLOHEXANONE EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-07-31 EP disclosed
EP-3013795-B1 PROCESS FOR CONCENTRATING A MIXTURE CONTAINING ORGANIC HYDROPEROXIDE EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-07-24 EP disclosed
US-10351506-B2 Purified plasticizers, production and use EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-07-16 US disclosed
US-20190176131-A1 Methods of Making Supported Mixed Metal Dehydrogenation Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2019-06-13 US disclosed
US-10286334-B2 Process for removing water and/or oxygen from organic liquid EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-05-14 US disclosed
EP-2847151-B1 HYDROGENATION PROCESS USING EGGSHELL CATALYSTS FOR THE REMOVAL OF OLEFINS EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-04-03 EP disclosed
EP-1778604-A1 PROCESS FOR PRODUCING SEC-BUTYL BENZENE ExxonMobil Chemical Patents Inc. (US) 2007-05-02 EP disclosed
WO-2007044139-A1 BISPHENOL-A PLANT YIELD ENHANCEMENT BADGER LICENSING LLC (US) 2007-04-19 WO disclosed
US-20060217281-A1 Oxidation system containing a macrocyclic metal complex, the production thereof and its use LANXESS B.V. (NL) 2006-09-28 US disclosed
WO-2006015826-A1 PROCESS FOR PRODUCING PHENOL AND METHYL ETHYL KETONE EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2006-02-16 WO disclosed
WO-2006015824-A1 PROCESS FOR PRODUCING SEC-BUTYL BENZENE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-02-16 WO disclosed
US-6720462-B2 VIA CATALYTIC OXIDATION OF AROMATIC HYDROCARBON TO HYDROPEROXIDE WHICH IS CLEAVED TO FORM PHENOL DERVIVATIVE AND KETONE DEGUSSA AG (DE) 2004-04-13 US disclosed
US-20030083527-A1 Method for producing aromatic alcohols, especially phenol CREAVIS GESELLSCHAFT FUER TECHNOLOGY UND INNOVATION MBH (DE) 2003-05-01 US disclosed
US-6297403-B1 OXIDATION OF A (DI)ARYL METHANE OR METHYLENE DERIVATIVE IN PRESENCE OF AN AMINE OXIDE OR HYDROXYAMINE DERIVATIVE MEDIATOR; BY-PRODUCT INHIBITION Consortium für elektrochemische Industrie GmbH (DE) 2001-10-02 US disclosed
US-6242245-B1 DELIGNIFICATION BY ADDING SUSPENSION OF LACCASE, OXIDANT, MEDIATOR SUCH AS VIOLURIC ACID, AND XYLANASE TO AQUEOUS SUSPENSION OF LIGNIN MATERIAL AND MIXING; MEDIATOR DOES NOT DEACTIVATE ENZYME Consortium für elektrochemische Industrie GmbH (DE) 2001-06-05 US disclosed
US-6069282-A REACTION OF VINYL-, ALKYNYL- OR ARYL-METHANOLS WITH THE AID OF A MEDIATOR AND AN OXIDANT, WHEREIN THE MEDIATOR IS SELECTED FROM THE GROUP OF THE ALIPHATIC, CYCLOALIPHATIC, HETEROCYCLIC OR AROMATIC NO OR NOH CONTAINING COMPOUNDS CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 2000-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11213804-B2 Dehydrogenation catalysts and methods of making and using the same IDH2, ADH4, IDH1 KDM4E 1156/4885ERCC1 1492/4885FEN1 448/4885
US-10351506-B2 Purified plasticizers, production and use ALKBH3, FTO, ALK KDM4E 110/4885ERCC1 625/4885FEN1 494/4885
US-10286334-B2 Process for removing water and/or oxygen from organic liquid SORD, DUOX2, DCXR KDM4E 1980/4885ERCC1 3680/4885FEN1 4558/4885
US-20030083527-A1 Method for producing aromatic alcohols, especially phenol CYP2E1, AOC2, ADH1C KDM4E 791/4885ERCC1 1635/4885FEN1 841/4885
US-20190176131-A1 Methods of Making Supported Mixed Metal Dehydrogenation Catalysts SOD1, DNMT1, CA1 KDM4E 2158/4885ERCC1 1224/4885FEN1 389/4885
US-20190283002-A1 Dehydrogenation Catalysts and Methods of Making and Using the Same IDH2, ADH4, IDH1 KDM4E 1156/4885ERCC1 1492/4885FEN1 448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.