Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 9/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.39 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396337 | 0.86 | HTR7 (0.43) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL914745 | 0.86 | SLC6A12 (0.47) | MCHR1HRH3SLC6A12SLC6A13KCNH2 | |
| SCHEMBL29743948 | 0.86 | SLC6A12 (0.47) | MCHR1HRH3SLC6A12SLC6A13KCNH2 | |
| SCHEMBL4396410 | 0.86 | L3MBTL1 (0.40) | MCHR1HRH3ALDH1A1HPGDHTT | |
| SCHEMBL4405570 | 0.85 | TLR7 (0.43) | SIGMAR1TLR9TLR7HPGDHTT | |
| SCHEMBL4396992 | 0.84 | KMT2A (0.41) | MCHR1SIGMAR1KCNH2 | |
| SCHEMBL4401571 | 0.84 | HPGDS (0.39) | SIGMAR1 | |
| SCHEMBL4394199 | 0.84 | CHRM3 (0.41) | — | |
| SCHEMBL4406835 | 0.84 | CHRM3 (0.40) | MCHR1SIGMAR1KCNH2DRD2DRD3 | |
| SCHEMBL4410349 | 0.83 | HRH3 (0.42) | HRH3KCNH2ALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |