Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.38 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29708102 | 0.83 | EPHX2 (0.44) | PPARAEPHX2RECQLGLAHPGD | |
| SCHEMBL5498150 | 0.81 | CA2 (0.44) | PPARAEPHX2GRIA1CA1CA2 | |
| SCHEMBL9656661 | 0.81 | CA2 (0.44) | PPARAEPHX2GRIA1CA1CA2 | |
| SCHEMBL7159366 | 0.80 | CA2 (0.43) | PPARAEPHX2GRIA1CA1CA2 | |
| SCHEMBL28395873 | 0.76 | GMNN (0.35) | TSHRMAPK1TP53 | |
| SCHEMBL27882188 | 0.74 | TP53 (0.38) | PPARAEPHX2GRIA1CA1CA2 | |
| SCHEMBL29004802 | 0.73 | FAAH (0.57) | MAPK1BLM | |
| SCHEMBL4797176 | 0.73 | PPARA (0.41) | PPARAEPHX2RECQLGLAHPGD | |
| SCHEMBL11683157 | 0.72 | CNR1 (0.51) | TSHREPHX1 | |
| SCHEMBL11599714 | 0.72 | CNR1 (0.51) | TSHREPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090311136-A1 | Enzymatic antibacterial cleaner having high pH stability | MANNING JR JAMES T | 2009-12-17 | — | — | US | disclosed |
| US-20080000032-A1 | Use of Metal Complexes Having Bispyridylpyrimidine or Bispyridyltriazine Ligands as Catalysts for Reactions With Peroxy Compounds for Bleaching Coloured Stains on Hard Surfaces | CIBA SPECIALTY CHEMICALS CORP. | 2008-01-03 | — | — | US | disclosed |
| US-7183248-B2 | Enzymatic cleaner having high pH stability | TREYCO SUPPLY CO. (US) | 2007-02-27 | — | — | US | disclosed |
| EP-1740306-A1 | USE OF METAL COMPLEXES HAVING BISPYRIDYLPYRIMIDINE OR BISPYRIDYLTRIAZINE LIGANDS AS CATALYSTS FOR REACTIONS WITH PEROXY COMPOUNDS FOR BLEACHING COLOURED STAINS ON HARD SURFACES | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-01-10 | — | — | EP | disclosed |
| EP-1228175-B1 | Method for washing a soiled plastic in a dishwashing machine | UNILEVER PLC (GB) | 2006-01-18 | — | — | EP | disclosed |
| WO-2005105303-A1 | USE OF METAL COMPLEXES HAVING BISPYRIDYLPYRIMIDINE OR BISPYRIDYLTRIAZINE LIGANDS AS CATALYSTS FOR REACTIONS WITH PEROXY COMPOUNDS FOR BLEACHING COLOURED STAINS ON HARD SURFACES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-11-10 | — | — | WO | disclosed |
| EP-0893491-B1 | Automatic dishwashing compositions | UNILEVER NV (NL) | 2005-03-09 | — | — | EP | disclosed |
| EP-0846757-B1 | Machine dishwashing gel composition | UNILEVER NV (NL) | 2005-01-26 | — | — | EP | disclosed |
| EP-0998548-B1 | AUTOMATIC DISHWASHING COMPOSITIONS CONTAINING WATER SOLUBLE CATIONIC OR AMPHOTERIC POLYMERS | UNILEVER NV (NL) | 2004-09-29 | — | — | EP | disclosed |
| EP-0816481-B1 | Peracid granules containing citric acid monohydrate for improved dissolution rates | UNILEVER NV (NL) | 2004-09-15 | — | — | EP | disclosed |
| US-5200236-A | Spraying molten wax in a fluidized bed | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1993-04-06 | — | — | US | disclosed |
| EP-0510761-A1 | Wax-encapsulated particles and method for making same | UNILEVER N.V. (NL) | 1992-10-28 | — | — | EP | disclosed |
| US-5141664-A | Active material surrounded by protective coating | LEVER BROTHERS COMPANY, A DIVISION OF CONOPCO, INC. (US) | 1992-08-25 | — | — | US | disclosed |
| US-4919841-A | ADDING DISPERSION IN MELT TO WATER CONTAINING SURFACTANT, EMULSIFYING TO FORM CAPSULES, COOLING AND ANNEALING | LEVER BROTHERS COMPANY (US) | 1990-04-24 | — | — | US | disclosed |
| EP-0346034-A2 | Wax encapsulated actives and emulsion process for their production | UNILEVER PLC (GB) | 1989-12-13 | — | — | EP | disclosed |
| EP-0119641-B1 | AQUEOUS ALKALINE CLEANING COMPOSITION | UNILEVER N.V. (NL) | 1987-05-13 | — | — | EP | disclosed |
| US-4607036-A | Preservative compositions employing anti-microbial morpholine derivatives | LEVER BROTHERS COMPANY (US) | 1986-08-19 | — | — | US | disclosed |
| US-4528039-A | Alkaline cleaning compositions non-corrosive toward aluminum surfaces | LEVER BROTHERS COMPANY (US) | 1985-07-09 | — | — | US | disclosed |
| EP-0119641-A1 | Aqueous alkaline cleaning composition | UNILEVER N.V. (NL) | 1984-09-26 | — | — | EP | disclosed |
| US-4457322-A | SODIUM METASILICATE AND POTASSIUM CARBONATE | LEVER BROTHERS COMPANY (US) | 1984-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080000032-A1 | Use of Metal Complexes Having Bispyridylpyrimidine or Bispyridyltriazine Ligands as Catalysts for Reactions With Peroxy Compounds for Bleaching Coloured Stains on Hard Surfaces | TYR, DPY30, TET2 | CA1 3732/4885CA2 229/4885PPARA 2202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.