SCHEMBL442730

SCHEMBL442730

Cc1occc1SSc1ccoc1C

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 1/20 0.40
CRBN Q96SW2 1/20 0.40
ALOX5 P09917 2/20 0.39
KDM4E B2RXH2 2/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 2/20 0.33
ALDH1A1 P00352 1/20 0.33
ICAM1 P05362 1/20 0.33
SELE P16581 1/20 0.33
MAPK1 P28482 2/20 0.31
TSHR P16473 1/20 0.31
ESR2 Q92731 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4232983 0.90 DDB1 (0.38) DDB1CRBNALOX5KDM4ELMNA
SCHEMBL942962 0.87
SCHEMBL11697759 0.84 DDB1 (0.35) DDB1CRBNALOX5KDM4ELMNA
SCHEMBL5163981 0.83 LMNA (0.44) DDB1CRBNALOX5KDM4ELMNA
SCHEMBL27546995 0.82 DDB1 (0.34) DDB1CRBNALOX5KDM4ELMNA
SCHEMBL9509697 0.82 DDB1 (0.34) DDB1CRBNALOX5KDM4ELMNA
SCHEMBL757595 0.81
SCHEMBL4761975 0.79
Hydrogen Sulfide SCHEMBL28759434 0.79 ALDH1A1 (0.42) DDB1CRBNALOX5KDM4ELMNA
SCHEMBL6258941 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 US claimed
US-12568998-B2 Flavouring composition with balanced taste profile SYMRISE AG (DE) 2026-03-10 US claimed
EP-4615958-A1 CELL COMPOSITIONS Givaudan SA (CH) 2025-09-17 EP claimed
US-20250282994-A1 ETCHING COMPOSITIONS, METHODS OF TREATING SUBSTRATES USING THE SAME, AND METHODS OF MANUFACTURING INTEGRATED CIRCUIT DEVICES USING THE SAME SAMYOUNG PURE CHEMICALS CO., LTD. (KR) 2025-09-11 US claimed
EP-4444108-B1 ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT SYMRISE AG (DE) 2025-09-10 EP claimed
EP-4593631-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME Mars, Incorporated (US) 2025-08-06 EP claimed
EP-4565194-A1 ODOR AND COLORANT STABILIZED COMPOSITIONS Symrise AG (DE) 2025-06-11 EP claimed
US-20250163006-A1 New Coolants, and Preparations Containing Same SYMRISE AG (DE) 2025-05-22 US claimed
CN-119968127-A Animal food compositions with improved palatability and customizable properties and methods of making the same 玛氏公司 2025-05-09 CN claimed
CN-119924491-A Flavoring composition with balanced taste characteristics 西姆莱斯有限公司 2025-05-06 CN claimed
CN-1762231-A Natural paste-form meat taste essence and its preparation method SHANGHAI INST TECHNOLOGY (CN) 2006-04-26 CN claimed
CN-1045598-C Process for preparing di (2-methyl-3-furyl) dithioether BEIJING LIGHT INDUSTRY COLLEGE (CN) 1999-10-13 CN claimed
CN-1097747-A The preparation method of a kind of two (2-methyl-3-furyl) disulfide BEIJING LIGHT INDUSTRY COLLEGE (CN) 1995-01-25 CN claimed
US-4293579-A Flavoring with 3,5-di-(2-methylpropyl)-1,2,4-trithiolane INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-10-06 US claimed
US-4139649-A ROAST BEEF INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-02-13 US claimed
US-4041186-A ADJUVANTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-08-09 US claimed
US-4031256-A ORGANOLEPTIC, NUTTY TASTE INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-06-21 US claimed
US-4020175-A MEAT AROMA AND FLAVOR INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-04-26 US claimed
US-3985908-A 3-Furyl sulfides and foodstuff flavor compositions comprising same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-10-12 US claimed
US-3959509-A Flavoring foodstuffs using sulfur-containing compounds INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-05-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12568998-B2 Flavouring composition with balanced taste profile TAS2R20, TAS2R50, TAS2R40 DDB1 3659/4885CRBN 3481/4885ALOX5 3817/4885
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME PIGS, TAS2R13, CEL DDB1 3943/4885CRBN 1774/4885ALOX5 1465/4885
US-20250163006-A1 New Coolants, and Preparations Containing Same TTR, TAS2R5, TAS2R50 DDB1 4353/4885CRBN 3722/4885ALOX5 1209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.