Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4434170 | 1.00 | NPC1 (0.46) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL491429 | 0.73 | RAB9A (0.73) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL322062 | 0.73 | RAB9A (0.73) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL5233158 | 0.73 | ALDH1A1 (0.52) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL4690691 | 0.73 | ALDH1A1 (0.52) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL10905157 | 0.71 | BLM (0.46) | L3MBTL1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL14643620 | 0.71 | BLM (0.41) | L3MBTL1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL5803237 | 0.70 | ALDH1A1 (0.59) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL28552607 | 0.70 | ALDH1A1 (0.59) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL9343847 | 0.69 | CES2 (0.37) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4127719-A1 | METHOD FOR DETECTION OF CD16B | 52 North Health Ltd (GB) | 2023-02-08 | — | — | EP | disclosed |
| WO-2021198693-A1 | METHOD FOR DETECTION OF CD16B | 52 NORTH HEALTH LTD (GB) | 2021-10-07 | — | — | WO | disclosed |
| US-9901649-B2 | Block copolymers for therapeutic drug delivery | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2018-02-27 | — | — | US | disclosed |
| US-20170319704-A1 | BLOCK COPOLYMERS FOR THERAPEUTIC DRUG DELIVERY | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-11-09 | — | — | US | disclosed |
| US-9631050-B2 | Antimicrobial cationic polycarbonates | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2017-04-25 | — | — | US | disclosed |
| WO-2016207343-A1 | PEROXIDASE FUSION PROTEIN | TECHNISCHE UNIVERSITÄT GRAZ (AT) | 2016-12-29 | — | — | WO | disclosed |
| US-20160257782-A1 | ANTIMICROBIAL CATIONIC POLYCARBONATES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2016-09-08 | — | — | US | disclosed |
| US-8703197-B2 | Branched polyamines for delivery of biologically active materials | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-04-22 | — | — | US | disclosed |
| US-20140080215-A1 | BRANCHED POLYAMINES FOR DELIVERY OF BIOLOGICALLY ACTIVE MATERIALS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-03-20 | — | — | US | disclosed |
| EP-2114887-A1 | PYRIDINE BENZAMIDES AND PYRAZINE BENZAMIDES USED AS PKD INHIBITORS | Cancer Research Technology Limited (GB) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008074997-A1 | PYRIDINE BENZAMIDES AND PYRAZINE BENZAMIDES USED AS PKD INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2008-06-26 | — | — | WO | disclosed |
| CN-1893967-A | Peptide-drug conjugates for leukocyte internalization | UNIV KANSAS (US) | 2007-01-10 | — | — | CN | disclosed |
| EP-1257542-B1 | METHOD FOR PRODUCING 2-(1,2,4-TRIAZOL-1-YL)-ETHANOLS | BAYER CROPSCIENCE AG (DE) | 2004-12-01 | — | — | EP | disclosed |
| US-6720428-B2 | REACTING A HYDRAZINE DERIVATIVE WITH N-DIHALOGENOMETHYL-FORMAMIDINIUM HALIDE TO FORM 2-(1,2,4-TRIAZOL-1-YL)-ETHANOLS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-04-13 | — | — | US | disclosed |
| WO-2003062432-A1 | METHOD FOR INCREASING THE EFFICIENCY OF AN INHIBITOR OF TYROSINE KINASE ACTIVITY | RIBOPHARMA AG (DE) | 2003-07-31 | — | — | WO | disclosed |
| US-20030018201-A1 | Method for producing 2-(1,2,4-Triazol-1-yl)-ethanols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2003-01-23 | — | — | US | disclosed |
| US-4605706-A | REACTING NITRILE-FUNCTIONAL POLYMER WITH A HYDROXYLAMINE AND AN AMINO COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-08-12 | — | — | US | disclosed |
| US-4564659-A | NITRILE POLYMER, HYDROXYLAMINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-01-14 | — | — | US | disclosed |
| EP-0105201-A2 | Chelate resins, process for their production and their use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-04-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160257782-A1 | ANTIMICROBIAL CATIONIC POLYCARBONATES | VDR, GC, CYP24A1 | NPC1 102/4885RAB9A 3561/4885L3MBTL1 1684/4885 |
| US-20170319704-A1 | BLOCK COPOLYMERS FOR THERAPEUTIC DRUG DELIVERY | GSS, GSR, GSTP1 | NPC1 3282/4885RAB9A 3945/4885L3MBTL1 1709/4885 |
| US-20030018201-A1 | Method for producing 2-(1,2,4-Triazol-1-yl)-ethanols | ADH1C, ADH1A, ADH5 | NPC1 3493/4885RAB9A 2089/4885L3MBTL1 2574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.