SCHEMBL444781

SCHEMBL444781

CCCc1cccc(-c2ccccc2OP(=O)(Oc2ccccc2-c2cccc(CCC)c2CCC)Oc2ccccc2-c2cccc(CCC)c2CCC)c1CCC

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.39
CTSS P25774 1/20 0.39
CTSK P43235 1/20 0.39
LTB4R Q15722 2/20 0.38
LTB4R2 Q9NPC1 2/20 0.38
ELANE P08246 1/20 0.36
PPARD Q03181 1/20 0.33
HTR1A P08908 1/20 0.32
ADRA2A P08913 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
NISCH Q9Y2I1 1/20 0.32
HTT P42858 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
PPARA Q07869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL448370 0.89 ALOX5 (0.38) LTB4RLTB4R2ELANEPPARA
SCHEMBL444783 0.89 INPPL1 (0.42) CTSLCTSSCTSKLTB4RLTB4R2
SCHEMBL3259356 0.88 CTSL (0.42) CTSLCTSSCTSKLTB4RLTB4R2
SCHEMBL11807298 0.86 LTB4R (0.42) LTB4RLTB4R2ELANEPPARDPPARA
SCHEMBL446045 0.83 L3MBTL1 (0.37) HTTL3MBTL1GPR84
SCHEMBL1191886 0.82 ELANE (0.39) CTSLCTSSCTSKLTB4RLTB4R2
SCHEMBL4451537 0.81 LTB4R (0.43) LTB4RLTB4R2L3MBTL1
SCHEMBL29784818 0.81 PPARD (0.41) LTB4RLTB4R2PPARDHTR1AADRA2A
SCHEMBL1592156 0.81 PPARD (0.41) LTB4RLTB4R2PPARDHTR1AADRA2A
SCHEMBL707310 0.80 CTSL (0.38) CTSLCTSSCTSKLTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612880-B2 Engine lubricant optimization for advanced sustainable fuels ExxonMobil Technology and Engineering Company (US) 2026-04-28 US disclosed
US-12577493-B2 Bio-based lubricant compositions ExxonMobil Technology and Engineering Company (US) 2026-03-17 US disclosed
EP-4705417-A1 INTERNAL COMBUSTION ENGINE LUBRICANT ExxonMobil Technology and Engineering Company (US) 2026-03-11 EP disclosed
EP-4101919-B1 REFRIGERATOR OIL COMPOSITION AND REFRIGERATOR MIXTURE COMPOSITION IDEMITSU KOSAN CO (JP) 2025-09-17 EP disclosed
US-12384980-B2 Internal combustion engine lubricant ExxonMobil Technology and Engineering Company (US) 2025-08-12 US disclosed
US-20250215838-A1 ENGINE LUBRICANT OPTIMIZATION FOR ADVANCED SUSTAINABLE FUELS ExxonMobil Technology and Engineering Company (US) 2025-07-03 US disclosed
US-20240409840-A1 BIO-BASED LUBRICANT COMPOSITIONS ExxonMobil Technology and Engineering Company (US) 2024-12-12 US disclosed
US-20240368493-A1 INTERNAL COMBUSTION ENGINE LUBRICANT ExxonMobil Technology and Engineering Company (US) 2024-11-07 US disclosed
WO-2024229029-A1 INTERNAL COMBUSTION ENGINE LUBRICANT ExxonMobil Technology and Engineering Company (US) 2024-11-07 WO disclosed
US-11760952-B2 Lubricant thickener systems from modified tall oil fatty acids, lubricating compositions, and associated methods INGEVITY SOUTH CAROLINA, LLC (US) 2023-09-19 US disclosed
EP-1008643-A2 Refrigerator oil composition, and method of using the composition for lubrication IDEMITSU KOSAN COMPANY LIMITED (JP) 2000-06-14 EP disclosed
US-5972854-A PREVENTS BRAKE LINING OF CLUTCH OF AUTOMATIC TRANSMISSIONS FROM SHUDDERING IDEMITSU KOSAN CO., LTD. (JP) 1999-10-26 US disclosed
EP-0636682-B1 Fluid composition for fluid coupling TONEN CORP (JP) 1999-09-22 EP disclosed
EP-0812900-A2 Lubricating oil composition for automatic transmission IDEMITSU KOSAN COMPANY LIMITED (JP) 1997-12-17 EP disclosed
US-5656577-A CONSISTS OF POLYSILOXANE BASED OILS; THIADIAZOLE DERIVATIVES, AMINE ANTIOXIDANTS AND POSPHORIC OR THIOPHOSPHORIC AND OTHER PHOSPHORUS COMPOUNDS OR CARBAMATES AS WEAR PREVENTIVE; EXCELLENT VISCOSITY AND TORQUE STABILITY TONEN CORPORATION (JP) 1997-08-12 US disclosed
EP-0748863-A2 Traction drive fluid composition COSMO RESEARCH INSTITUTE (JP) 1996-12-18 EP disclosed
EP-0397507-B1 Silicone fluids for viscous couplings TONEN CORP (JP) 1995-03-15 EP disclosed
EP-0636682-A1 Fluid composition for fluid coupling Tonen Corporation (JP) 1995-02-01 EP disclosed
US-5332515-A Polysiloxane, phosphorus type anti-wear agent TONEN CORPORATION (JP) 1994-07-26 US disclosed
EP-0397507-A1 Silicone fluids for viscous couplings Tonen Corporation (JP) 1990-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577493-B2 Bio-based lubricant compositions DEGS1, DSG1, DEK CTSL 4715/4885CTSS 4272/4885CTSK 2266/4885
US-12612880-B2 Engine lubricant optimization for advanced sustainable fuels TST, TCF4, MLLT1 CTSL 4691/4885CTSS 4083/4885CTSK 4084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.