SCHEMBL448370

SCHEMBL448370

CCCCc1cccc(-c2ccccc2OP(=O)(Oc2ccccc2-c2cccc(CCCC)c2CCCC)Oc2ccccc2-c2cccc(CCCC)c2CCCC)c1CCCC

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.38
PTGS2 P35354 1/20 0.38
ELANE P08246 2/20 0.38
CTSG P08311 1/20 0.38
PPARA Q07869 2/20 0.37
LTB4R Q15722 1/20 0.37
LTB4R2 Q9NPC1 1/20 0.37
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36
PPARG P37231 1/20 0.36
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL448372 0.89 HTR2A (0.42) ALOX5PTGS2ELANECTSGPPARA
SCHEMBL444781 0.89 CTSL (0.39) ELANEPPARALTB4RLTB4R2
SCHEMBL8079852 0.88 THRA (0.40) ALOX5PTGS2ELANECTSGPPARA
SCHEMBL385367 0.87 ALOX5 (0.43) ALOX5PTGS2ELANECTSGPPARA
SCHEMBL1191997 0.83 ELANE (0.41) ALOX5PTGS2ELANECTSGPPARA
SCHEMBL766607 0.82 PTGS2 (0.49) ALOX5PTGS2PPARALTB4RLTB4R2
SCHEMBL4446488 0.82 LTB4R (0.41) PPARALTB4RLTB4R2
SCHEMBL1592695 0.82 THRA (0.47) ALOX5PTGS2PPARATHRATHRB
SCHEMBL29761930 0.82 THRA (0.47) ALOX5PTGS2PPARATHRATHRB
SCHEMBL3861457 0.81 PPARA (0.49) ALOX5PTGS2PPARALTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7527902-B2 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION (US) 2009-05-05 US claimed
US-20070026328-A1 Photoreceptor layer having phosphorus-containing lubricant XEROX CORPORATION 2007-02-01 US claimed
US-20070026330-A1 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION 2007-02-01 US claimed
US-12612880-B2 Engine lubricant optimization for advanced sustainable fuels ExxonMobil Technology and Engineering Company (US) 2026-04-28 US disclosed
US-12577493-B2 Bio-based lubricant compositions ExxonMobil Technology and Engineering Company (US) 2026-03-17 US disclosed
EP-4705417-A1 INTERNAL COMBUSTION ENGINE LUBRICANT ExxonMobil Technology and Engineering Company (US) 2026-03-11 EP disclosed
EP-4101919-B1 REFRIGERATOR OIL COMPOSITION AND REFRIGERATOR MIXTURE COMPOSITION IDEMITSU KOSAN CO (JP) 2025-09-17 EP disclosed
US-12384980-B2 Internal combustion engine lubricant ExxonMobil Technology and Engineering Company (US) 2025-08-12 US disclosed
US-20250215838-A1 ENGINE LUBRICANT OPTIMIZATION FOR ADVANCED SUSTAINABLE FUELS ExxonMobil Technology and Engineering Company (US) 2025-07-03 US disclosed
US-20240409840-A1 BIO-BASED LUBRICANT COMPOSITIONS ExxonMobil Technology and Engineering Company (US) 2024-12-12 US disclosed
US-20240368493-A1 INTERNAL COMBUSTION ENGINE LUBRICANT ExxonMobil Technology and Engineering Company (US) 2024-11-07 US disclosed
US-5747429-A SILICONE OIL TONEN CORPORATION (JP) 1998-05-05 US disclosed
EP-0812900-A2 Lubricating oil composition for automatic transmission IDEMITSU KOSAN COMPANY LIMITED (JP) 1997-12-17 EP disclosed
US-5656577-A CONSISTS OF POLYSILOXANE BASED OILS; THIADIAZOLE DERIVATIVES, AMINE ANTIOXIDANTS AND POSPHORIC OR THIOPHOSPHORIC AND OTHER PHOSPHORUS COMPOUNDS OR CARBAMATES AS WEAR PREVENTIVE; EXCELLENT VISCOSITY AND TORQUE STABILITY TONEN CORPORATION (JP) 1997-08-12 US disclosed
EP-0748863-A2 Traction drive fluid composition COSMO RESEARCH INSTITUTE (JP) 1996-12-18 EP disclosed
EP-0719853-A2 Fluid composition for use in fluid coupling Tonen Corporation (JP) 1996-07-03 EP disclosed
EP-0397507-B1 Silicone fluids for viscous couplings TONEN CORP (JP) 1995-03-15 EP disclosed
EP-0636682-A1 Fluid composition for fluid coupling Tonen Corporation (JP) 1995-02-01 EP disclosed
US-5332515-A Polysiloxane, phosphorus type anti-wear agent TONEN CORPORATION (JP) 1994-07-26 US disclosed
EP-0397507-A1 Silicone fluids for viscous couplings Tonen Corporation (JP) 1990-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577493-B2 Bio-based lubricant compositions DEGS1, DSG1, DEK ALOX5 488/4885PTGS2 2082/4885ELANE 348/4885
US-12612880-B2 Engine lubricant optimization for advanced sustainable fuels TST, TCF4, MLLT1 ALOX5 1297/4885PTGS2 3952/4885ELANE 3276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.