Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL443280 | 1.00 | ALDH1A1 (0.63) | ALDH1A1KDM4EL3MBTL1GLAPTGS2 | |
| SCHEMBL445025 | 0.91 | ALDH1A1 (0.61) | ALDH1A1KDM4EL3MBTL1GLAPTGS2 | |
| SCHEMBL445024 | 0.91 | ALDH1A1 (0.61) | ALDH1A1KDM4EL3MBTL1GLAPTGS2 | |
| SCHEMBL20186922 | 0.89 | ALDH1A1 (0.74) | ALDH1A1KDM4EL3MBTL1GLAPTGS2 | |
| SCHEMBL12633723 | 0.89 | ALDH1A1 (0.74) | ALDH1A1KDM4EL3MBTL1GLAPTGS2 | |
| SCHEMBL11557679 | 0.89 | ALDH1A1 (0.74) | ALDH1A1KDM4EL3MBTL1GLAPTGS2 | |
| SCHEMBL255410 | 0.89 | ALDH1A1 (0.74) | ALDH1A1KDM4EL3MBTL1GLAPTGS2 | |
| SCHEMBL11588746 | 0.89 | ALDH1A1 (0.74) | ALDH1A1KDM4EL3MBTL1GLAPTGS2 | |
| SCHEMBL14129042 | 0.89 | ALDH1A1 (0.69) | ALDH1A1KDM4EL3MBTL1GLAPTGS2 | |
| SCHEMBL11420710 | 0.88 | ALDH1A1 (0.59) | ALDH1A1KDM4EL3MBTL1GLAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065430-A1 | Application of Metal Amidoborane and Their Derivatives in Reduction Reaction | DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2012-03-15 | — | — | US | claimed |
| JP-11116540-A | — | — | None | — | — | JP | disclosed |
| US-12441700-B2 | Hydrogenation of imines with RU complexes | FIRMENICHI SA (CH) | 2025-10-14 | — | — | US | disclosed |
| EP-3931176-B1 | HYDROGENATION OF IMINES WITH RU COMPLEXES | FIRMENICH & CIE (CH) | 2024-02-14 | — | — | EP | disclosed |
| US-11891408-B2 | Application of lithium 4-methoxyaniline in catalysis of hydroboration reaction of imine and borane | SOOCHOW UNIVERSITY (CN) | 2024-02-06 | — | — | US | disclosed |
| US-11498901-B2 | Hydrogenation of imines with Ru complexes | FIRMENICH SA (CH) | 2022-11-15 | — | — | US | disclosed |
| US-20220162181-A1 | HYDROGENATION OF IMINES WITH RU COMPLEXES | FIRMENICH SA (CH) | 2022-05-26 | — | — | US | disclosed |
| CN-109134402-B | Chiral sulfonamide derivative and preparation method and application thereof | 中山大学 | 2022-05-24 | — | — | CN | disclosed |
| US-20220008887-A1 | Swellable Organically Modified Silica as Nanoreactors | APPALACHIAN STATE UNIVERSITY | 2022-01-13 | — | — | US | disclosed |
| US-20210371382-A1 | HYDROGENATION OF IMINES WITH RU COMPLEXES | FIRMENICH SA (CH) | 2021-12-02 | — | — | US | disclosed |
| US-20080214547-A1 | METHODS AND COMPOSITIONS OF TRAIL-DEATH RECEPTOR AGONISTS/ACTIVATORS | UNIVERSITY OF MARYLAND, BALTIMORE | 2008-09-04 | — | — | US | disclosed |
| US-7355075-B2 | Reacting a compound of a hydroxyl functionality, a carbonyl functionality, or both a hydroxyl functionality and a carbonyl functionality with reactant having an amine functionality in the presence of ordered porous manganese-based octahedral molecular sieves and an oxygen gas | THE UNIVERSITY OF CONNECTICUT (US) | 2008-04-08 | — | — | US | disclosed |
| US-7355075-B2 | Reacting a compound of a hydroxyl functionality, a carbonyl functionality, or both a hydroxyl functionality and a carbonyl functionality with reactant having an amine functionality in the presence of ordered porous manganese-based octahedral molecular sieves and an oxygen gas | THE UNIVERSITY OF CONNECTICUT (US) | 2008-04-08 | — | — | US | disclosed |
| US-20070027344-A1 | METHOD OF PRODUCING IMINES | THE UNIVERSITY OF CONNECTICUT (US) | 2007-02-01 | — | — | US | disclosed |
| US-20070027344-A1 | METHOD OF PRODUCING IMINES | THE UNIVERSITY OF CONNECTICUT (US) | 2007-02-01 | — | — | US | disclosed |
| JP-H11116540-A | SYNTHESIS OF AMINES AND DIAMINES | FUKUDA GAKUEN | 1999-04-27 | — | — | JP | disclosed |
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12441700-B2 | Hydrogenation of imines with RU complexes | HRH3, HNMT, HRH4 | ALDH1A1 3213/4885KDM4E 3630/4885L3MBTL1 3177/4885 |
| US-20210371382-A1 | HYDROGENATION OF IMINES WITH RU COMPLEXES | HRH3, HRH4, HRH2 | ALDH1A1 2869/4885KDM4E 2995/4885L3MBTL1 3806/4885 |
| US-20070027344-A1 | METHOD OF PRODUCING IMINES | MT-CO2, INMT, SCO2 | ALDH1A1 1989/4885KDM4E 2592/4885L3MBTL1 4357/4885 |
| US-20220008887-A1 | Swellable Organically Modified Silica as Nanoreactors | MSN, SORD, OGA | ALDH1A1 2617/4885KDM4E 3400/4885L3MBTL1 2674/4885 |
| US-20080214547-A1 | METHODS AND COMPOSITIONS OF TRAIL-DEATH RECEPTOR AGONISTS/ACTIVATORS | BID, BAD, MCL1 | ALDH1A1 3768/4885KDM4E 3451/4885L3MBTL1 2487/4885 |
| US-11498901-B2 | Hydrogenation of imines with Ru complexes | HRH3, HRH4, HRH2 | ALDH1A1 2869/4885KDM4E 2995/4885L3MBTL1 3806/4885 |
| US-11891408-B2 | Application of lithium 4-methoxyaniline in catalysis of hydroboration reaction of imine and borane | ME1, MCM4, INMT | ALDH1A1 3287/4885KDM4E 368/4885L3MBTL1 129/4885 |
| US-20220162181-A1 | HYDROGENATION OF IMINES WITH RU COMPLEXES | HRH3, HNMT, HRH4 | ALDH1A1 3213/4885KDM4E 3630/4885L3MBTL1 3177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.