SCHEMBL443280

SCHEMBL443280

Cc1ccc(C=Nc2ccccc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.63
KDM4E B2RXH2 5/20 0.63
L3MBTL1 Q9Y468 3/20 0.63
GLA P06280 1/20 0.63
PTGS2 P35354 5/20 0.56
CA2 P00918 4/20 0.56
PTGS1 P23219 2/20 0.56
CA12 O43570 2/20 0.56
CA9 Q16790 2/20 0.56
SMN1; SMN2 Q16637 6/20 0.54
RAB9A P51151 4/20 0.54
NPC1 O15118 3/20 0.54
GAA P10253 4/20 0.49
HPGD P15428 2/20 0.49
USP2 O75604 2/20 0.49
CA1 P00915 3/20 0.48
MAPT P10636 4/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
NPSR1 Q6W5P4 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL443279 1.00 ALDH1A1 (0.63) ALDH1A1KDM4EL3MBTL1GLAPTGS2
SCHEMBL445025 0.91 ALDH1A1 (0.61) ALDH1A1KDM4EL3MBTL1GLAPTGS2
SCHEMBL445024 0.91 ALDH1A1 (0.61) ALDH1A1KDM4EL3MBTL1GLAPTGS2
SCHEMBL20186922 0.89 ALDH1A1 (0.74) ALDH1A1KDM4EL3MBTL1GLAPTGS2
SCHEMBL12633723 0.89 ALDH1A1 (0.74) ALDH1A1KDM4EL3MBTL1GLAPTGS2
SCHEMBL11557679 0.89 ALDH1A1 (0.74) ALDH1A1KDM4EL3MBTL1GLAPTGS2
SCHEMBL255410 0.89 ALDH1A1 (0.74) ALDH1A1KDM4EL3MBTL1GLAPTGS2
SCHEMBL11588746 0.89 ALDH1A1 (0.74) ALDH1A1KDM4EL3MBTL1GLAPTGS2
SCHEMBL14129042 0.89 ALDH1A1 (0.69) ALDH1A1KDM4EL3MBTL1GLAPTGS2
SCHEMBL11420710 0.88 ALDH1A1 (0.59) ALDH1A1KDM4EL3MBTL1GLAPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117304223-A Picer ligand rare earth metal catalyst and preparation method and application thereof 安徽师范大学 2023-12-29 CN claimed
US-20120065430-A1 Application of Metal Amidoborane and Their Derivatives in Reduction Reaction DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) 2012-03-15 US claimed
US-7934888-B2 Marine anti-foulant system and methods for using same VIV SUPPRESSION, INC. (US) 2011-05-03 US claimed
US-20090185867-A1 MARINE ANTI-FOULANT SYSTEM AND METHODS FOR USING SAME ASSET INTEGRITY MANAGEMENT SOLUTIONS, L.L.C., D/B/A AIMS INTERNATIONAL 2009-07-23 US claimed
JP-11116540-A None JP disclosed
US-12441700-B2 Hydrogenation of imines with RU complexes FIRMENICHI SA (CH) 2025-10-14 US disclosed
CN-118955540-A Synthesis method of alpha-amino organoboron compound 中国科学院大连化学物理研究所 2024-11-15 CN disclosed
EP-3931176-B1 HYDROGENATION OF IMINES WITH RU COMPLEXES FIRMENICH & CIE (CH) 2024-02-14 EP disclosed
US-11891408-B2 Application of lithium 4-methoxyaniline in catalysis of hydroboration reaction of imine and borane SOOCHOW UNIVERSITY (CN) 2024-02-06 US disclosed
CN-117304223-A Picer ligand rare earth metal catalyst and preparation method and application thereof 安徽师范大学 2023-12-29 CN disclosed
US-11845055-B2 Swellable organically modified silica as nanoreactors APPALACHIAN STATE UNIVERSITY (US) 2023-12-19 US disclosed
US-11845068-B2 Use of n-butyllithium for catalyzing hydroboration of imine and borane SOOCHOW UNIVERSITY (CN) 2023-12-19 US disclosed
EP-1123950-A1 Method for preventing settlement of aquatic fouling organisms Nippon Paint Co., Ltd. (JP) 2001-08-16 EP disclosed
JP-H11116540-A SYNTHESIS OF AMINES AND DIAMINES FUKUDA GAKUEN 1999-04-27 JP disclosed
US-5861435-A PAINTING BENZYLIDENE ANILINE DERIVATIVE WHICH THICKENS TO PRODUCE BIO-JELLY; GELATION NIPPON PAINT CO., LTD. (JP) 1999-01-19 US disclosed
EP-0702065-A2 Method for preventing settlement of aquatic fouling organisms Nippon Paint Co., Ltd. (JP) 1996-03-20 EP disclosed
US-4224340-A Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds WILLIAM H. RORER, INC. (US) 1980-09-23 US disclosed
US-4214003-A ANTIINFLAMMATORY AGENTS WILLIAM H. RORER, INC. (US) 1980-07-22 US disclosed
US-4197314-A WITH A DIPHENYL NITRONE WILLIAM H. RORER, INC. (US) 1980-04-08 US disclosed
US-4153722-A ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE WILLIAM H. RORER, INC. (US) 1979-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12441700-B2 Hydrogenation of imines with RU complexes HRH3, HNMT, HRH4 ALDH1A1 3213/4885KDM4E 3630/4885L3MBTL1 3177/4885
US-11845068-B2 Use of n-butyllithium for catalyzing hydroboration of imine and borane INMT, SLC6A12, ICMT ALDH1A1 4186/4885KDM4E 3810/4885L3MBTL1 134/4885
US-11845055-B2 Swellable organically modified silica as nanoreactors MSN, SORD, OGA ALDH1A1 2617/4885KDM4E 3400/4885L3MBTL1 2674/4885
US-11891408-B2 Application of lithium 4-methoxyaniline in catalysis of hydroboration reaction of imine and borane ME1, MCM4, INMT ALDH1A1 3287/4885KDM4E 368/4885L3MBTL1 129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.