Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6845342 | 0.91 | THRB (0.39) | TSHRCA1CA2THRB | |
| SCHEMBL6845510 | 0.88 | THRB (0.44) | TSHRCA1CA2THRB | |
| SCHEMBL15728704 | 0.88 | THRB (0.44) | TSHRCA1CA2THRB | |
| SCHEMBL16182389 | 0.86 | — | — | |
| SCHEMBL21300746 | 0.82 | THRB (0.38) | TSHRCA1CA2THRB | |
| SCHEMBL13673070 | 0.82 | TSHR (0.46) | ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL1725397 | 0.81 | — | — | |
| SCHEMBL4451275 | 0.80 | — | — | |
| SCHEMBL11554765 | 0.79 | ADRB2 (0.41) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| SCHEMBL223099 | 0.78 | ADRB2 (0.45) | ADRB2ADRB1ADRB3TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250084111-A1 | METHOD FOR PREPARING 4-(HYDROXYMETHYLPHOSPHINYL)-2-OXOBUTANOIC ACID | ZHEJIANG WYNCA CHEMICAL INDUSTRY GROUP CO., LTD (CN) | 2025-03-13 | — | — | US | claimed |
| US-20250084110-A1 | METHOD FOR PREPARING 4-(HYDROXYMETHYLPHOSPHINYL)-2-OXOBUTANOIC ACID | ZHEJIANG WYNCA CHEMICAL INDUSTRY GROUP CO., LTD (CN) | 2025-03-13 | — | — | US | claimed |
| CN-113316580-B | Preparation method of L-glufosinate | CJ第一制糖株式会社 | 2024-11-19 | — | — | CN | claimed |
| CN-117964654-A | Synthesis method of arginate-ammonium phosphonate | 南京盛德创赢生物科技有限公司 | 2024-05-03 | — | — | CN | claimed |
| WO-2024051120-A1 | PREPARATION METHOD FOR 4-(HYDROXYMETHYLPHOSPHINYL)-2-OXOBUTYRIC ACID | 浙江新安化工集团股份有限公司 | 2024-03-14 | — | — | WO | claimed |
| WO-2024051119-A1 | PREPARATION METHOD FOR 4-(HYDROXYMETHYLPHOSPHINYL)-2-OXOBUTYRIC ACID | 浙江新安化工集团股份有限公司 | 2024-03-14 | — | — | WO | claimed |
| CN-113316580-A | Preparation method of L-glufosinate-ammonium | CJ第一制糖株式会社 | 2021-08-27 | — | — | CN | claimed |
| US-9714206-B2 | Methyl-iodide-free carbonylation of an alcohol to its homologous aldehyde and/or alcohol | EASTMAN CHEMICAL COMPANY (US) | 2017-07-25 | — | — | US | claimed |
| US-20160185701-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | EASTMAN CHEMICAL COMPANY (US) | 2016-06-30 | — | — | US | claimed |
| US-6770779-B1 | ALKYLATION OF YELLOW PHOSPHORUS WITH ALKYLATING IN BASE TO FORM METAL SALT OF ALKYLPHOSPHONOUS, PHOSPHOROUS AND HYPOPHOSPHOROUS ACIDS; ESTERIFICATION | CLARIANT GMBH (DE) | 2004-08-03 | — | — | US | claimed |
| EP-1055679-B1 | Process for the preparation of alkylphosphonous acid esters | CLARIANT GMBH (DE) | 2003-08-06 | — | — | EP | claimed |
| EP-1055676-B1 | Process for the preparation of dialkylphosphinic acids and their salts | CLARIANT GMBH (DE) | 2003-08-06 | — | — | EP | claimed |
| EP-1055677-B1 | Process for the preparation of phosphinic acid esters | CLARIANT GMBH (DE) | 2003-03-05 | — | — | EP | claimed |
| US-6359171-B1 | ALKYLATION PHOSPHORUS; ESTERIFICATION | CLARIANT GMBH (DE) | 2002-03-19 | — | — | US | claimed |
| US-6278012-B1 | REACTING ELEMENTAL YELLOW PHOSPHORUS WITH ALKYLATING AGENTS IN PRESENCE OF A BASE TO GIVE A MIXTURE COMPRISING ALKYLPHOSPHONOUS, PHOSPHOROUS AND HYPOPHOSPHOROUS ACIDS; ESTERIFICATION; ISOLATING AND ADDING TO OLEFIN COMPOUND | CLARIANT GMBH (DE) | 2001-08-21 | — | — | US | claimed |
| EP-4720078-A1 | FLAME-RETARDANT POLYURETHANE AND USES THEREOF | Clariant International Ltd (CH) | 2026-04-08 | — | — | EP | disclosed |
| US-20250084110-A1 | METHOD FOR PREPARING 4-(HYDROXYMETHYLPHOSPHINYL)-2-OXOBUTANOIC ACID | ZHEJIANG WYNCA CHEMICAL INDUSTRY GROUP CO., LTD (CN) | 2025-03-13 | — | — | US | disclosed |
| US-6359171-B1 | ALKYLATION PHOSPHORUS; ESTERIFICATION | CLARIANT GMBH (DE) | 2002-03-19 | — | — | US | disclosed |
| US-6278012-B1 | REACTING ELEMENTAL YELLOW PHOSPHORUS WITH ALKYLATING AGENTS IN PRESENCE OF A BASE TO GIVE A MIXTURE COMPRISING ALKYLPHOSPHONOUS, PHOSPHOROUS AND HYPOPHOSPHOROUS ACIDS; ESTERIFICATION; ISOLATING AND ADDING TO OLEFIN COMPOUND | CLARIANT GMBH (DE) | 2001-08-21 | — | — | US | disclosed |
| US-4434108-A | POSTEMERGENCE AND PREEMERGENCE HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1984-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185701-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | ADH1C, ADH5, ADH1A | ADRB2 1883/4885ADRB1 1988/4885ADRB3 2655/4885 |
| US-20250084111-A1 | METHOD FOR PREPARING 4-(HYDROXYMETHYLPHOSPHINYL)-2-OXOBUTANOIC ACID | CA2, CA7, CA6 | ADRB2 2802/4885ADRB1 2360/4885ADRB3 2113/4885 |
| US-20250084110-A1 | METHOD FOR PREPARING 4-(HYDROXYMETHYLPHOSPHINYL)-2-OXOBUTANOIC ACID | HPD, PPIP5K2, IP6K2 | ADRB2 1342/4885ADRB1 1740/4885ADRB3 1840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.