Dimethylamine

Dimethylamine

SCHEMBL447383

CCC(N)OC(=O)CN.CNC

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
MGAM O43451 2/20 0.30
GAA P10253 2/20 0.30
SI P14410 2/20 0.30
MGAM2 Q2M2H8 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL4565839 0.83 MGAM (0.30) MGAMGAASIMGAM2
SCHEMBL27969593 0.78
SCHEMBL2633798 0.78
Dimethylamine SCHEMBL21986549 0.76 LMNA (0.58) LMNA
SCHEMBL29037400 0.75
SCHEMBL27807086 0.74 ALDH1A1 (0.48) LMNA
Dimethylamine SCHEMBL1139784 0.73 METAP2 (0.30)
SCHEMBL11879324 0.73 MAPT (0.36) KDM4ELMNA
SCHEMBL2110683 0.72 TSHR (0.35)
SCHEMBL2566927 0.72 ALDH1A1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2983678-B1 ANTI-MICROBIAL COMPOSITION ARETEON PTE LTD (SG) 2019-01-02 EP disclosed
US-20170049679-A1 ORAL AND DENTAL HYGIENE AND CLEANING AGENTS FOR REDUCING TOOTH DISCOLORATION HENKEL AG & CO. KGAA (DE) 2017-02-23 US disclosed
US-20160250139-A1 HAIR TREATMENT AGENTS HAVING SUBSTITUTED SILICONE(S) HENKEL AG & CO. KGAA (DE) 2016-09-01 US disclosed
US-20160015735-A1 ANTI-MICROBIAL COMPOSITION ARETEON PTE LTD (SG) 2016-01-21 US disclosed
US-20150164761-A1 HAIR TREATMENT COMPOSITIONS COMPRISING SELECTED FATTY ACID AMIDES AND SELECTED FRAGRANCES HENKEL AG & CO. KGAA (DE) 2015-06-18 US disclosed
US-20150150775-A1 HAIR TREATMENT COMPOSITIONS COMPRISING SELECTED FRAGRANCES AND SELECTED COMPLEXES OF ACIDIC PROTEIN HYDROLYSATES AND BASIC FATTY ACID AMIDOAMINES HENKEL AG & CO. KGAA (DE) 2015-06-04 US disclosed
US-8999939-B2 Hair treatment agents having low-dose oligopeptides HENKEL AG & CO. KGAA (DE) 2015-04-07 US disclosed
US-20140248230-A1 HAIR CARE TREATMENT AGENT HENKEL AG & CO. KGAA (DE) 2014-09-04 US disclosed
US-20140248228-A1 HAIR TREATMENT COMPOSITION WITH CATIONIC CARE SUBSTANCE AND UV FILTER HENKEL AG & CO. KGAA (DE) 2014-09-04 US disclosed
US-20130216490-A1 HAIR TREATMENT AGENTS HAVING LOW-DOSE OLIGOPEPTIDES HENKEL AG & CO. KGAA (DE) 2013-08-22 US disclosed
WO-2004006869-A1 PRODUCTS COMPRISING A DRY APPLICATOR, AN AQUEOUS PHASE AND A LIPID PHASE JOHNSON & JOHNSON GMBH (DE) 2004-01-22 WO disclosed
WO-2004006880-A1 DRY PRODUCTS COMPRISING AN APPLICATOR AND A WAX PHASE JOHNSON & JOHNSON GMBH (DE) 2004-01-22 WO disclosed
WO-2003005982-A1 PRODUCTS COMPRISING A SHEET AND A LIPID AND AQUEOUS PHASE JOHNSON & JOHNSON GMBH (DE) 2003-01-23 WO disclosed
WO-2003005983-A1 DRY PRODUCTS COMPRISING A SHEET AND TWO PHASES JOHNSON & JOHNSON GMBH (DE) 2003-01-23 WO disclosed
EP-1275370-A1 Products comprising a sheet and a lipid and aqueous phase Johnson and Johnson GmbH (DE) 2003-01-15 EP disclosed
EP-1275371-A1 Dry products comprising a sheet and two phases Johnson and Johnson GmbH (DE) 2003-01-15 EP disclosed
US-5939081-A THICKENING AN OIL-IN-WATER EMULSION BY ADDING A THICKENING AGENT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1999-08-17 US disclosed
US-5795978-A CONTAINING ALKYL OR ALKENL OLIGOGLYCOSIDE AND FATTY ALCOHOL;COSMETICS, DRUGS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1998-08-18 US disclosed
US-5716418-A OXIDATION HAIR COLOR DYES; NONTOXIC, COLORFASTNESS, ABSORPTION, RECEPTIVITY HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1998-02-10 US disclosed
US-5609650-A HAIR DYES, OXIDATION WITH ATMOSPHERIC OXYGEN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN 1997-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160015735-A1 ANTI-MICROBIAL COMPOSITION CUTA, ALG1, TYR KDM4E 2520/4885LMNA 2848/4885MGAM 416/4885
US-20130216490-A1 HAIR TREATMENT AGENTS HAVING LOW-DOSE OLIGOPEPTIDES FOLH1, ENPEP, PSAP KDM4E 2689/4885LMNA 3795/4885MGAM 1411/4885
US-20160250139-A1 HAIR TREATMENT AGENTS HAVING SUBSTITUTED SILICONE(S) EGFR, CUTA, MSH6 KDM4E 1358/4885LMNA 1521/4885MGAM 3814/4885
US-20170049679-A1 ORAL AND DENTAL HYGIENE AND CLEANING AGENTS FOR REDUCING TOOTH DISCOLORATION H1-2, H1-0, H1-5 KDM4E 4209/4885LMNA 2776/4885MGAM 1568/4885
US-20140248228-A1 HAIR TREATMENT COMPOSITION WITH CATIONIC CARE SUBSTANCE AND UV FILTER MC1R, POLR1C, CUTA KDM4E 2933/4885LMNA 104/4885MGAM 3016/4885
US-20150164761-A1 HAIR TREATMENT COMPOSITIONS COMPRISING SELECTED FATTY ACID AMIDES AND SELECTED FRAGRANCES FAAH2, FAAH, FADS1 KDM4E 1486/4885LMNA 3064/4885MGAM 4579/4885
US-20150150775-A1 HAIR TREATMENT COMPOSITIONS COMPRISING SELECTED FRAGRANCES AND SELECTED COMPLEXES OF ACIDIC PROTEIN HYDROLYSATES AND BASIC FATTY ACID AMIDOAMINES CUTA, FAAH2, FAAH KDM4E 3882/4885LMNA 1654/4885MGAM 3666/4885
US-20140248230-A1 HAIR CARE TREATMENT AGENT H1-4, H1-0, H1-10 KDM4E 1076/4885LMNA 885/4885MGAM 4151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.