Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.37 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | BUB1 | O43683 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4494579 | 0.92 | ALDH1A1 (0.43) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4490040 | 0.84 | GFER (0.47) | KDM4EALDH1A1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL4492336 | 0.83 | AR (0.47) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4504902 | 0.82 | AR (0.57) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4559832 | 0.82 | TP53 (0.46) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL4490747 | 0.82 | PGR (0.43) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4498679 | 0.80 | CCNC (0.36) | KDM4EALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL4488093 | 0.80 | VDR (0.40) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL4504869 | 0.80 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL4485732 | 0.79 | KMT2A (0.47) | KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504429-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | claimed |