Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4494579 | 0.90 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4EHTTVDR | |
| SCHEMBL4559832 | 0.89 | TP53 (0.46) | ALDH1A1HPGDGAAHTTVDR | |
| SCHEMBL4485732 | 0.86 | KMT2A (0.47) | CCR2KMT2APPARGPLA2G1BPLA2G2A | |
| SCHEMBL4484664 | 0.85 | CFTR (0.45) | ALDH1A1CCR2LMNASLC16A3MCTS1 | |
| SCHEMBL4492983 | 0.84 | ERCC5 (0.47) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4477472 | 0.84 | PGR (0.48) | PGRALDH1A1HPGDKDM4EGAA | |
| SCHEMBL4485664 | 0.82 | KDM4E (0.40) | ALDH1A1KDM4EVDRMAPTMEN1 | |
| SCHEMBL4488093 | 0.81 | VDR (0.40) | ALDH1A1HTTVDRMAPTMEN1 | |
| SCHEMBL4490040 | 0.80 | GFER (0.47) | ALDH1A1HPGDKDM4EGAAHTT | |
| SCHEMBL4492336 | 0.79 | AR (0.47) | ALDH1A1HPGDKDM4EGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504429-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | claimed |