Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 6/20 | 0.45 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.43 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.43 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | EDNRB | P24530 | 2/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | YWHAH | Q04917 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4490040 | 0.88 | GFER (0.47) | PLA2G2AEDNRBFEN1PLA2G1B | |
| SCHEMBL4494579 | 0.87 | ALDH1A1 (0.43) | KMT2APOLB | |
| SCHEMBL4559832 | 0.86 | TP53 (0.46) | KMT2AFEN1 | |
| SCHEMBL4490747 | 0.86 | PGR (0.43) | KMT2APLA2G2ASLC16A3MCTS1CCR2 | |
| SCHEMBL4484664 | 0.82 | CFTR (0.45) | SLC16A3SLC16A1MCTS1CCR2FEN1 | |
| SCHEMBL4492983 | 0.82 | ERCC5 (0.47) | KMT2AFEN1 | |
| SCHEMBL4477472 | 0.82 | PGR (0.48) | KMT2APLA2G2ACCR2FEN1 | |
| SCHEMBL4482567 | 0.80 | PLA2G2A (0.43) | KMT2APLA2G2APLA2G1B | |
| SCHEMBL4485664 | 0.79 | KDM4E (0.40) | KMT2APOLB | |
| SCHEMBL4492336 | 0.77 | AR (0.47) | KMT2APOLBFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504429-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | claimed |