Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4494579 | 0.89 | ALDH1A1 (0.43) | ARPOLBTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL4484664 | 0.89 | CFTR (0.45) | ARFEN1ALDH1A1GRIA2GRIA4 | |
| SCHEMBL4490040 | 0.83 | GFER (0.47) | GAAFEN1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4485664 | 0.83 | KDM4E (0.40) | POLBTSHRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4493743 | 0.83 | GRIA2 (0.39) | POLBTSHRSMN1; SMN2ALDH1A1GRIA2 | |
| SCHEMBL4504902 | 0.82 | AR (0.57) | ARPOLBALDH1A1KDM4EMEN1 | |
| SCHEMBL4490747 | 0.79 | PGR (0.43) | GAASMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL4559832 | 0.79 | TP53 (0.46) | GAAFEN1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL4488093 | 0.77 | VDR (0.40) | POLBTSHRSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4504869 | 0.77 | ALDH1A1 (0.42) | POLBTSHRSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504429-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | claimed |