SCHEMBL454726

SCHEMBL454726

CCCCCCCCCCCC=CC(=O)NCS(=O)(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 3/20 0.54
CNR1 P21554 5/20 0.49
CNR2 P34972 5/20 0.49
PSMB11 A5LHX3 1/20 0.47
PSMA7 O14818 1/20 0.47
PSMB1 P20618 1/20 0.47
PSMA1 P25786 1/20 0.47
PSMA2 P25787 1/20 0.47
PSMA3 P25788 1/20 0.47
PSMA4 P25789 1/20 0.47
PSMB8 P28062 1/20 0.47
PSMB9 P28065 1/20 0.47
PSMA5 P28066 1/20 0.47
PSMB4 P28070 1/20 0.47
PSMB6 P28072 1/20 0.47
PSMB5 P28074 1/20 0.47
PSMB10 P40306 1/20 0.47
PSMB3 P49720 1/20 0.47
PSMB2 P49721 1/20 0.47
PSMA6 P60900 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22498741 0.84 EPHX2 (0.62) EPHX2CNR1CNR2PPARA
SCHEMBL18428385 0.83 ZDHHC20 (0.59) EPHX2CNR1CNR2
SCHEMBL10016663 0.83 ZDHHC20 (0.59) EPHX2CNR1CNR2
SCHEMBL3614630 0.83 ZDHHC20 (0.59) EPHX2CNR1CNR2
SCHEMBL10016656 0.83 ZDHHC20 (0.59) EPHX2CNR1CNR2
SCHEMBL2089328 0.83 ZDHHC20 (0.59) EPHX2CNR1CNR2
SCHEMBL10454080 0.83 ZDHHC20 (0.59) EPHX2CNR1CNR2
SCHEMBL10016644 0.83 ZDHHC20 (0.59) EPHX2CNR1CNR2
SCHEMBL2089610 0.81 CNR1 (0.59) EPHX2CNR1CNR2PSMB11PSMA7
SCHEMBL5673282 0.81 CNR1 (0.59) EPHX2CNR1CNR2PSMB11PSMA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3386476-A1 COMPOSITION COMPRISING A POLYMER CONTAINING A SULFONIC MONOMER AND A PYRIDINEDICARBOXYLIC ACID DERIVATIVE, AND COSMETIC TREATMENT METHOD L'Oréal (FR) 2018-10-17 EP claimed
WO-2017097849-A1 COMPOSITION COMPRISING A POLYMER CONTAINING A SULFONIC MONOMER AND A PYRIDINEDICARBOXYLIC ACID DERIVATIVE, AND COSMETIC TREATMENT METHOD L'OREAL (FR) 2017-06-15 WO claimed
US-7217298-B2 Ready-to-use bleaching compositions, preparation process and bleaching process L'OREAL S.A. (FR) 2007-05-15 US claimed
EP-1325729-B1 Composition containing a silicone copolymer and either a polymer from an ethylenically unsaturated monomer with sulfonic groups or an organic powder; uses thereof, especially in cosmetics OREAL (FR) 2006-04-19 EP claimed
US-20040235700-A1 Ready-to-use bleaching compositions, preparation process and bleaching process L'OREAL S.A. (FR) 2004-11-25 US claimed
EP-4547208-B1 PROCESS FOR REMOVING THE COLOUR FROM PREVIOUSLY DYED KERATINOUS HAIR FIBRES OREAL (FR) 2026-05-27 EP disclosed
US-12636246-B2 Process for colouring hair keratin fibers, comprising the application of a composition comprising at least one (poly)carbodiimide compound and a composition comprising at least one associative polymer and a particular compound L'OREAL (FR) 2026-05-26 US disclosed
CN-122094656-A Method for dyeing hair keratin fibres, comprising the step of washing the hair keratin fibres with a particular composition and subsequently applying to the hair keratin fibres a particular dyeing composition 2026-05-26 CN disclosed
EP-4734951-A1 COMPOSITION FOR CONDITIONING THE HAIR L'OREAL (FR) 2026-05-06 EP disclosed
EP-3389618-B2 PROCESS FOR TREATING KERATIN FIBRES USING AN AQUEOUS COMPOSITION COMPRISING A COMBINATION OF PARTICULAR ALKOXYSILANES OREAL (FR) 2026-04-22 EP disclosed
US-12576015-B2 Antimicrobial mixture containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one and an alcohol compound, and cosmetic composition containing same L'OREAL (FR) 2026-03-17 US disclosed
US-12576016-B2 Composition containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one, a preservative and/or antioxidant, a surfactant and a polymer, and the method for processing keratin materials from the composition L'OREAL (FR) 2026-03-17 US disclosed
US-20040074015-A1 Oxidising composition for treating keratinous materials based on amphiphilic polymers of at least an ethylenically unsaturated monomer containing a sulfonic group and comprising a hydrophobic part L'OREAL (FR) 2004-04-22 US disclosed
US-20040071641-A1 Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers SOCIETE L'OREAL S.A. (FR) 2004-04-15 US disclosed
US-20040062728-A1 Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers SOCIETE L'OREAL, S.A. (FR) 2004-04-01 US disclosed
US-20030171479-A1 Composition containing a silicone copolymer and an amps-like polymer and/or organic powder L'OREAL (FR) 2003-09-11 US disclosed
US-20030157047-A1 Cosmetic composition for removing make-up from and clening the skin L'OREAL (FR) 2003-08-21 US disclosed
US-20030108577-A1 Cosmetic and/or dermatological acid composition containing an amphiphilic polymer L'OREAL (FR) 2003-06-12 US disclosed
US-20030050201-A1 Cleansing composition containing an amphiphilic polymer L'OREAL (FR) 2003-03-13 US disclosed
US-20030036490-A1 Stable composition with high electrolyte content containing an amphiphilic polymer L'OREAL (FR) 2003-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030157047-A1 Cosmetic composition for removing make-up from and clening the skin CUTA, DEGS1, LAGE3 EPHX2 113/4885CNR1 1848/4885CNR2 2243/4885
US-20040062728-A1 Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers CUTA, PCNA, DSG1 EPHX2 1382/4885CNR1 3909/4885CNR2 3521/4885
US-12576015-B2 Antimicrobial mixture containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one and an alcohol compound, and cosmetic composition containing same EBP, CUTA, HAO2 EPHX2 2258/4885CNR1 4844/4885CNR2 4820/4885
US-20040071641-A1 Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers CUTA, DSG1, PCNA EPHX2 1415/4885CNR1 4173/4885CNR2 3770/4885
US-20030108577-A1 Cosmetic and/or dermatological acid composition containing an amphiphilic polymer KRT18, DSG1, CUTA EPHX2 410/4885CNR1 2702/4885CNR2 2470/4885
US-12576016-B2 Composition containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one, a preservative and/or antioxidant, a surfactant and a polymer, and the method for processing keratin materials from the composition KRT18, BAK1, GPX4 EPHX2 1795/4885CNR1 4884/4885CNR2 4878/4885
US-12636246-B2 Process for colouring hair keratin fibers, comprising the application of a composition comprising at least one (poly)carbodiimide compound and a composition comprising at least one associative polymer and a particular compound KRT18, CYC1, CYBA EPHX2 2020/4885CNR1 1698/4885CNR2 1543/4885
US-20030171479-A1 Composition containing a silicone copolymer and an amps-like polymer and/or organic powder SPPL2B, CALCB, CALCA EPHX2 4393/4885CNR1 4480/4885CNR2 4488/4885
US-20030036490-A1 Stable composition with high electrolyte content containing an amphiphilic polymer KRT18, DSG1, SCNN1A EPHX2 832/4885CNR1 4041/4885CNR2 4155/4885
US-20040074015-A1 Oxidising composition for treating keratinous materials based on amphiphilic polymers of at least an ethylenically unsaturated monomer containing a sulfonic group and comprising a hydrophobic part KRT18, DSG1, CUTA EPHX2 147/4885CNR1 3845/4885CNR2 3159/4885
US-20030050201-A1 Cleansing composition containing an amphiphilic polymer UGCG, SGMS1, SGMS2 EPHX2 2742/4885CNR1 2358/4885CNR2 2136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.