Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.59 |
| ▸ | NCF1 | P14598 | 1/20 | 0.56 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.55 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11139655 | 0.98 | HRH3 (0.69) | HRH3ALDH1A1KDM4ESMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL7404903 | 0.96 | HRH3 (0.67) | HRH3ALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL4547912 | 0.96 | ALDH1A1 (0.59) | HRH3ALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL17465252 | 0.86 | CHKA (0.71) | HRH3ALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL14847024 | 0.85 | HRH3 (0.67) | HRH3ALDH1A1KDM4ESMN1; SMN2HRH4 | |
| SCHEMBL28645590 | 0.85 | HRH3 (0.61) | HRH3ALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL1935806 | 0.85 | HRH3 (0.67) | HRH3ALDH1A1KDM4ESMN1; SMN2HRH4 | |
| SCHEMBL14923999 | 0.85 | ALDH1A1 (0.65) | HRH3ALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL6894415 | 0.85 | LMNA (0.68) | HRH3ALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL10178474 | 0.83 | HRH3 (0.59) | HRH3ALDH1A1KDM4EHRH4NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230043159-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | DISC MEDICINE, INC. | 2023-02-09 | — | — | US | disclosed |
| EP-3444124-B1 | METHOD OF MAKING A FUNCTIONALIZED ELASTOMER | GOODYEAR TIRE & RUBBER (US) | 2020-08-05 | — | — | EP | disclosed |
| US-10654828-B2 | Indole derivatives and uses thereof | NOVARTIS AG (CH) | 2020-05-19 | — | — | US | disclosed |
| US-10633350-B2 | Diphenyl derivatives and uses thereof | NOVARTIS AG (CH) | 2020-04-28 | — | — | US | disclosed |
| US-10472434-B2 | Functionalized elastomer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2019-11-12 | — | — | US | disclosed |
| US-10301400-B2 | Method of making a functionalized elastomer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2019-05-28 | — | — | US | disclosed |
| WO-2019053090-A1 | DIPHENYL DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2019-03-21 | — | — | WO | disclosed |
| US-20190077773-A1 | DIPHENYL DERIVATIVES AND USES THEREOF | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. | 2019-03-14 | — | — | US | disclosed |
| US-20190055219-A1 | INDOLE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2019-02-21 | — | — | US | disclosed |
| US-20190055332-A1 | FUNCTIONALIZED ELASTOMER | MIZUHO BANK, LTD., AS ADMINISTRATIVE AGENT | 2019-02-21 | — | — | US | disclosed |
| US-7504411-B2 | 2,3,6-Trisubstituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-03-17 | — | — | US | disclosed |
| US-7504411-B2 | 2,3,6-Trisubstituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-03-17 | — | — | US | disclosed |
| WO-2008154601-A1 | ANTI-VIRAL INHIBITORS AND METHODS OF USE | GENELABS TECHNOLOGIES, INC. (US) | 2008-12-18 | — | — | WO | disclosed |
| US-20080255155-A1 | KINASE INHIBITORS AND USES THEREOF | METHLYGENE INC. (CA) | 2008-10-16 | — | — | US | disclosed |
| US-20080064718-A1 | INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY | METHYLGENE INC. (CA) | 2008-03-13 | — | — | US | disclosed |
| US-20080004273-A1 | Inhibitors of protein tyrosine kinase activity | METHYLGENE, INC. (CA) | 2008-01-03 | — | — | US | disclosed |
| US-20080004273-A1 | Inhibitors of protein tyrosine kinase activity | METHYLGENE, INC. (CA) | 2008-01-03 | — | — | US | disclosed |
| US-20070027166-A1 | Pyrazolo pyrimidines useful as aurora kinase inhibitors | SUNESIS PHARMACEUTICALS, INC. | 2007-02-01 | — | — | US | disclosed |
| US-20070004675-A1 | Inhibitors of VEGF receptor and HGF receptor signaling | METHYLGENE, INC. | 2007-01-04 | — | — | US | disclosed |
| US-20070004675-A1 | Inhibitors of VEGF receptor and HGF receptor signaling | METHYLGENE, INC. | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077773-A1 | DIPHENYL DERIVATIVES AND USES THEREOF | MYOF, NGF, MUSK | HRH3 4847/4885ALDH1A1 921/4885KDM4E 2168/4885 |
| US-20070004675-A1 | Inhibitors of VEGF receptor and HGF receptor signaling | HGF, MET, FLT1 | HRH3 1501/4885ALDH1A1 1649/4885KDM4E 4094/4885 |
| US-20080255155-A1 | KINASE INHIBITORS AND USES THEREOF | ABL1, MAP3K20, MAP3K1 | HRH3 3157/4885ALDH1A1 3553/4885KDM4E 840/4885 |
| US-20080064718-A1 | INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY | HGF, ERBB2, MET | HRH3 2228/4885ALDH1A1 3139/4885KDM4E 2282/4885 |
| US-20190055219-A1 | INDOLE DERIVATIVES AND USES THEREOF | MYLK2, MYOF, MUSK | HRH3 4051/4885ALDH1A1 1676/4885KDM4E 2754/4885 |
| US-20070027166-A1 | Pyrazolo pyrimidines useful as aurora kinase inhibitors | AURKA, AURKB, AURKC | HRH3 1799/4885ALDH1A1 3764/4885KDM4E 951/4885 |
| US-10633350-B2 | Diphenyl derivatives and uses thereof | MYOF, NGF, MUSK | HRH3 4847/4885ALDH1A1 921/4885KDM4E 2168/4885 |
| US-20230043159-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | MMP7, MATR3, SPINT2 | HRH3 3172/4885ALDH1A1 3877/4885KDM4E 1948/4885 |
| US-10654828-B2 | Indole derivatives and uses thereof | MYLK2, MYOF, MUSK | HRH3 4051/4885ALDH1A1 1676/4885KDM4E 2754/4885 |
| US-20080004273-A1 | Inhibitors of protein tyrosine kinase activity | HGF, ERBB2, MET | HRH3 2228/4885ALDH1A1 3139/4885KDM4E 2282/4885 |
| US-10301400-B2 | Method of making a functionalized elastomer | MUS81, RTN4, KCNN4 | HRH3 285/4885ALDH1A1 3649/4885KDM4E 1357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.