Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 8/20 | 1.00 |
| ▸ | SLC5A2 | P31639 | 7/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.91 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.91 |
| ▸ | RELA | Q04206 | 2/20 | 0.91 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.73 |
| ▸ | GAA | P10253 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | ATM | Q13315 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | TTR | P02766 | 1/20 | 0.73 |
| ▸ | ESR1 | P03372 | 1/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5084404 | 0.95 | NFKB1 (1.00) | SLC5A1SLC5A2NFKB1NFKB2RELA | |
| SCHEMBL1938352 | 0.91 | SLC5A1 (0.84) | SLC5A1SLC5A2NFKB1NFKB2RELA | |
| SCHEMBL1682159 | 0.89 | NFKB1 (0.83) | SLC5A1SLC5A2NFKB1NFKB2RELA | |
| Asebogenin SCHEMBL4740064 | 0.89 | NFKB1 (0.88) | SLC5A1SLC5A2NFKB1NFKB2RELA | |
| SCHEMBL28079027 | 0.88 | SLC5A1 (0.78) | SLC5A1SLC5A2NFKB1NFKB2RELA | |
| SCHEMBL2282039 | 0.87 | NFKB1 (0.83) | SLC5A1SLC5A2NFKB1NFKB2RELA | |
| SCHEMBL15457885 | 0.86 | NFKB1 (0.83) | SLC5A1SLC5A2NFKB1NFKB2RELA | |
| SCHEMBL1224101 | 0.86 | SLC5A1 (0.75) | SLC5A1SLC5A2NFKB1NFKB2RELA | |
| SCHEMBL8115827 | 0.86 | NFKB1 (0.77) | SLC5A1SLC5A2NFKB1NFKB2RELA | |
| Phloretin SCHEMBL27910960 | 0.85 | SLC5A1 (0.93) | SLC5A1SLC5A2NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4219569-A | CARBOCYCLIC KETONES | THE UPJOHN COMPANY (US) | 1980-08-26 | — | — | US | claimed |
| US-20260048027-A1 | METHYLATED PHLORETIN ANALOGS AS INHIBITORS OF SGLT2 | NESTLE SA (CH) | 2026-02-19 | — | — | US | disclosed |
| EP-4572749-A1 | METHYLATED PHLORETIN ANALOGS AS INHIBITORS OF SGLT2 | Société des Produits Nestlé S.A. (CH) | 2025-06-25 | — | — | EP | disclosed |
| CN-119654142-A | Methylated phloretin analogs as inhibitors of SGLT2 | 雀巢产品有限公司 | 2025-03-18 | — | — | CN | disclosed |
| US-20250084049-A1 | POLYCATIONIC SALTS OF PHENOLIC COMPOUNDS AND USES THEREOF | FIRMENICH INCORPORATED (US) | 2025-03-13 | — | — | US | disclosed |
| CN-118955261-A | Synthesis process of phloretin and derivative thereof and application of phloretin and derivative thereof as antioxidant in plastic products | 营口风光新材料股份有限公司 | 2024-11-15 | — | — | CN | disclosed |
| WO-2024038011-A1 | METHYLATED PHLORETIN ANALOGS AS INHIBITORS OF SGLT2 | Société des Produits Nestlé S.A. (CH) | 2024-02-22 | — | — | WO | disclosed |
| WO-2023278394-A1 | POLYCATIONIC SALTS OF PHENOLIC COMPOUNDS AND USES THEREOF | FIRMENICH INCORPORATED (US) | 2023-01-05 | — | — | WO | disclosed |
| US-10800725-B2 | Arylpropionyl-triketone antibacterial agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-10-13 | — | — | US | disclosed |
| US-20130289128-A1 | ARYLPROPIONYL-TRIKETONE ANTIBACTERIAL AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-10-31 | — | — | US | disclosed |
| WO-2012033846-A1 | ARYLPROPIONYL-TRIKETONE ANTIBACTERIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-03-15 | — | — | WO | disclosed |
| WO-2010120029-A1 | COMPOSITION COMPRISING THE EXTRACT OF ANEMARRHENA ASPHODELOIDES BUNGE OR THE COMPOUNDS ISOLATED FROM THE SAME FOR PREVENTING AND TREATING LIPID METABOLISM DISORDER | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2010-10-21 | — | — | WO | disclosed |
| US-7446120-B2 | Peptidomimetic modulators of cell adhesion | ADHEREX TECHNOLOGIES, INC. (CA) | 2008-11-04 | — | — | US | disclosed |
| US-20080260829-A1 | Bone morphogenic proteins (bmp); cell adhesion modulating agent; peptidomimetics of cyclic peptides comprising classical cadherin cell adhesion recognition (CAR) sequences; modulate cell adhesion and improve drug delivery | NEW YORK SOCIETY FOR THE RUPTURED AND CRIPPLED MAINTAINING THE HOSPITAL FOR SPECIAL SURGERY (US) | 2008-10-23 | — | — | US | disclosed |
| US-20080081831-A1 | PEPTIDOMIMETIC MODULATORS OF CELL ADHESION | ADHEREX TECHNOLOGIES, INC. (CA) | 2008-04-03 | — | — | US | disclosed |
| US-7268115-B2 | Cyclic peptides; three-dimensional structures; screening; anticancer agents; angiogenesis inhibitors; drug delivery | ADHEREX TECHNOLOGIES, INC. (CA) | 2007-09-11 | — | — | US | disclosed |
| US-4219569-A | CARBOCYCLIC KETONES | THE UPJOHN COMPANY (US) | 1980-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250084049-A1 | POLYCATIONIC SALTS OF PHENOLIC COMPOUNDS AND USES THEREOF | PGC, SLC5A6, PUF60 | SLC5A1 207/4885SLC5A2 70/4885NFKB1 1051/4885 |
| US-20080260829-A1 | Bone morphogenic proteins (bmp); cell adhesion modulating agent; peptidomimetics of cyclic peptides comprising classical cadherin cell adhesion recognition (CAR) sequences; modulate cell adhesion and improve drug delivery | BMP1, BMP2, BMP4 | SLC5A1 2500/4885SLC5A2 3211/4885NFKB1 2073/4885 |
| US-20080081831-A1 | PEPTIDOMIMETIC MODULATORS OF CELL ADHESION | CDH1, EPCAM, VCAM1 | SLC5A1 4027/4885SLC5A2 4268/4885NFKB1 3904/4885 |
| US-20130289128-A1 | ARYLPROPIONYL-TRIKETONE ANTIBACTERIAL AGENTS | POLR2H, POLR2A, POLR2E | SLC5A1 2423/4885SLC5A2 3409/4885NFKB1 425/4885 |
| US-10800725-B2 | Arylpropionyl-triketone antibacterial agents | POLR2H, POLR2A, POLR2E | SLC5A1 2423/4885SLC5A2 3409/4885NFKB1 425/4885 |
| US-20260048027-A1 | METHYLATED PHLORETIN ANALOGS AS INHIBITORS OF SGLT2 | SLC5A2, SLC5A1, SLC2A1 | SLC5A1 2/4885SLC5A2 1/4885NFKB1 4036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.