Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 4/20 | 0.67 |
| ▸ | CA2 known ✓ | P00918 | 4/20 | 0.67 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.67 |
| ▸ | CES1 | P23141 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 2/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11588707 | 0.96 | CA1 (0.67) | CA1CA2CES2CES1ACHE | |
| P-Nitrophenylphosphate SCHEMBL168768 | 0.90 | CA1 (0.69) | CA1CA2CES2CES1ACHE | |
| SCHEMBL867575 | 0.89 | CA1 (0.64) | CA1CA2CES2CES1ACHE | |
| P-Nitrophenylphosphate SCHEMBL844914 | 0.88 | CA1 (0.67) | CA1CA2CES2CES1ACHE | |
| P-Nitrophenylphosphate SCHEMBL11103558 | 0.88 | CA1 (0.67) | CA1CA2CES2CES1ACHE | |
| P-Nitrophenylphosphate SCHEMBL11104501 | 0.88 | CA1 (0.67) | CA1CA2CES2CES1ACHE | |
| P-Nitrophenylphosphate SCHEMBL11322610 | 0.88 | CA1 (0.67) | CA1CA2CES2CES1ACHE | |
| P-Nitrophenylphosphate SCHEMBL11322617 | 0.88 | CA1 (0.67) | CA1CA2CES2CES1ACHE | |
| P-Nitrophenylphosphate SCHEMBL30776755 | 0.88 | CA1 (0.67) | CA1CA2CES2CES1ACHE | |
| SCHEMBL11588710 | 0.88 | CA1 (0.62) | CA1CA2CES2CES1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957627-B | Preparation method of polyester with low byproduct tetrahydrofuran | 万华化学集团股份有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-114957627-A | Preparation method of polyester with low byproduct tetrahydrofuran | 万华化学集团股份有限公司 | 2022-08-30 | — | — | CN | claimed |
| EP-4100394-B1 | INHIBITORS OF ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) AND METHODS OF USE THEREOF | STINGRAY THERAPEUTICS INC (US) | 2026-04-08 | — | — | EP | disclosed |
| EP-4682193-A1 | RESIN COMPOSITION FOR FOAM MOLDING, FOAM MOLDED BODY, METHOD FOR PRODUCING FOAM MOLDED BODY, FOAM ELECTRICAL WIRE, AND METHOD FOR PRODUCING FOAM ELECTRICAL WIRE | Daikin Industries, Ltd. (JP) | 2026-01-21 | — | — | EP | disclosed |
| EP-4682192-A1 | RESIN COMPOSITION FOR FOAM MOLDING, FOAM MOLDED BODY, AND METHOD FOR PRODUCING FOAM MOLDED BODY | DAIKIN INDUSTRIES, LTD. (JP) | 2026-01-21 | — | — | EP | disclosed |
| EP-4667515-A1 | RESIN COMPOSITION FOR FOAM MOLDING, INTERLAYER INSULATOR, LAYERED BODY, AND FOAMED ELECTRIC WIRE | National University Corporation Yamagata University (JP) | 2025-12-24 | — | — | EP | disclosed |
| US-12391690-B2 | Compounds as autotaxin inhibitors and pharmaceutical compositions comprising the same | LIGACHEM BIOSCIENCES INC. (KR) | 2025-08-19 | — | — | US | disclosed |
| CN-115362145-B | External nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) inhibitors and methods of use thereof | 斯汀格瑞治疗股份有限公司 | 2025-05-02 | — | — | CN | disclosed |
| US-20250099493-A1 | PHOSPHONATES AS INHIBITORS OF ENPP1 AND CDNP | STINGRAY THERAPEUTICS INC (US) | 2025-03-27 | — | — | US | disclosed |
| US-20250092018-A1 | INHIBITORS OF ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) AND METHODS OF USE THEREOF | STINGRAY THERAPEUTICS INC (US) | 2025-03-20 | — | — | US | disclosed |
| CN-119056492-A | Filter membrane for removing DNA pollution in water and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2024-12-03 | — | — | CN | disclosed |
| EP-1327619-A1 | Method for hydrolyzing phosphodiester with a catalyst comprising a cyclic phenol sulfide metal complex | Cosmo Research Institute (JP) | 2003-07-16 | — | — | EP | disclosed |
| EP-1327618-A1 | Method for analyzing hydrogen peroxide with a catalyst comprising a cyclic phenol sulfide metal complex | Cosmo Research Institute (JP) | 2003-07-16 | — | — | EP | disclosed |
| US-6472167-B1 | MEASURE VIABLE BACTERIA AS A FUNCTION OF THE ACTIVITIES OF BACTERIAL ENZYMES, PHOSPHATASES, GLUCOSIDASES, AND AMINOPEPTIDASES; PRESENCE DETECTED BY A FLUORESCENT SIGNAL | BIOCONTROL SYSTEMS, INC. | 2002-10-29 | — | — | US | disclosed |
| US-6387650-B1 | INNOCULATING AND INCUBATING TEST SAMPLE ON GROWTH MEDIUM HAVING ENZYME SUBSTRATES FOR PHOSPHATASE, GLYCOSIDASE, AND PEPTIDASE, THEN DETECTING OR MEASURING SIGNAL PRODUCED BY THE HYDROLYSIS OF THE SUBSTRATES | BIOCONTROL SYSTEMS, INC. | 2002-05-14 | — | — | US | disclosed |
| EP-1123930-A9 | sYCLIC PHENOL SULFIDE-METAL COMPLEXES, CATALYSTS COMPRISING THE SAME AND ANALYTICAL METHODS FOR HYDROGEN PEROXIDE | Cosmo Research Institute (JP) | 2001-11-14 | — | — | EP | disclosed |
| EP-1123930-A1 | sYCLIC PHENOL SULFIDE-METAL COMPLEXES, CATALYSTS COMPRISING THE SAME AND ANALYTICAL METHODS FOR HYDROGEN PEROXIDE | Cosmo Research Institute (JP) | 2001-08-16 | — | — | EP | disclosed |
| WO-2001010870-A1 | TRANSITION METAL COMPLEXES OF N,N',N'-TRIALKYL- CIS,CIS-1,3,5-TRIAMINOCYCLOHEXANE AND RELATED COMPOSITIONS AND METHODS OF SYNTHESIS AND USE | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2001-02-15 | — | — | WO | disclosed |
| EP-0870054-A1 | METHOD AND COMPOSITION FOR DETECTING BACTERIAL CONTAMINATION IN FOOD PRODUCTS | IDEXX LABORATORIES, INC. (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1996040980-A1 | METHOD AND COMPOSITION FOR DETECTING BACTERIAL CONTAMINATION IN FOOD PRODUCTS | IDEXX LABORATORIES, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12391690-B2 | Compounds as autotaxin inhibitors and pharmaceutical compositions comprising the same | ENPP2, PLA2G10, LPCAT1 | CA1 2336/4885CA2 1914/4885THRB 3927/4885 |
| US-20250099493-A1 | PHOSPHONATES AS INHIBITORS OF ENPP1 AND CDNP | ENPP1, ENPP3, PPP1R1B | CA1 4529/4885CA2 3926/4885THRB 954/4885 |
| US-20250092018-A1 | INHIBITORS OF ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) AND METHODS OF USE THEREOF | ENPP1, ENPP3, PDE7A | CA1 3460/4885CA2 2244/4885THRB 3119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.