Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958941 | 1.00 | MMP2 (0.47) | MMP2MMP9MMP14STSTSHR | |
| SCHEMBL10499208 | 1.00 | MMP2 (0.47) | MMP2MMP9MMP14STSTSHR | |
| SCHEMBL8958823 | 0.96 | MMP2 (0.50) | MMP2MMP9MMP14STSTSHR | |
| SCHEMBL15602838 | 0.89 | DGKA (0.51) | MMP2MMP9MMP14STSTSHR | |
| SCHEMBL20959757 | 0.89 | DGKA (0.51) | MMP2MMP9MMP14STSTSHR | |
| SCHEMBL10775759 | 0.88 | MMP2 (0.57) | MMP2MMP9MMP14STSTSHR | |
| SCHEMBL9352787 | 0.87 | S1PR3 (0.50) | MMP2MMP9MMP14STSTSHR | |
| SCHEMBL9352816 | 0.87 | S1PR3 (0.50) | MMP2MMP9MMP14STSTSHR | |
| SCHEMBL4629619 | 0.87 | S1PR3 (0.50) | MMP2MMP9MMP14STSTSHR | |
| Hydrochloric Acid SCHEMBL10701272 | 0.87 | MMP2 (0.56) | MMP2MMP9MMP14STSTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1563048-B1 | PROCESS OF REMOVING STAINS | RECKITT BENCKISER NV (NL) | 2008-05-07 | — | — | EP | claimed |
| US-7255112-B2 | Process of removing stains | RECKITT BENCKISER N.V. (NL) | 2007-08-14 | — | — | US | claimed |
| US-20060042662-A1 | Process of removing stains | RECKITT BENCKISER FINISH B.V. (NL) | 2006-03-02 | — | — | US | claimed |
| EP-1563048-A1 | PROCESS OF REMOVING STAINS | Reckitt Benckiser N.V. (NL) | 2005-08-17 | — | — | EP | claimed |
| WO-2004048507-A1 | PROCESS OF REMOVING STAINS | RECKITT BENCKISER N.V. (NL) | 2004-06-10 | — | — | WO | claimed |
| EP-1563048-B1 | PROCESS OF REMOVING STAINS | RECKITT BENCKISER NV (NL) | 2008-05-07 | — | — | EP | disclosed |
| US-7255112-B2 | Process of removing stains | RECKITT BENCKISER N.V. (NL) | 2007-08-14 | — | — | US | disclosed |
| US-20060042662-A1 | Process of removing stains | RECKITT BENCKISER FINISH B.V. (NL) | 2006-03-02 | — | — | US | disclosed |
| EP-1563048-A1 | PROCESS OF REMOVING STAINS | Reckitt Benckiser N.V. (NL) | 2005-08-17 | — | — | EP | disclosed |
| EP-1543763-A1 | Ingredient dispenser for automatic dishwashers | UNILEVER N.V. (NL) | 2005-06-22 | — | — | EP | disclosed |
| WO-2004048507-A1 | PROCESS OF REMOVING STAINS | RECKITT BENCKISER N.V. (NL) | 2004-06-10 | — | — | WO | disclosed |
| EP-0202698-B2 | P-sulphophenyl alkyl carbonates and their use as bleaching activators | AKZO NOBEL NV (NL) | 1996-01-24 | — | — | EP | disclosed |
| US-5043089-A | Bleach activators | AKZO N.V. (NL) | 1991-08-27 | — | — | US | disclosed |
| EP-0384912-A2 | Hydroxamate bleach stabilizer | MONSANTO COMPANY (US) | 1990-08-29 | — | — | EP | disclosed |
| EP-0384911-A2 | Stabilized compositions containing peroxygen compounds | MONSANTO COMPANY (US) | 1990-08-29 | — | — | EP | disclosed |
| EP-0202698-B1 | P-SULPHOPHENYL ALKYL CARBONATES AND THEIR USE AS BLEACHING ACTIVATORS | Akzo Nobel N.V. (NL) | 1989-10-25 | — | — | EP | disclosed |
| EP-0202698-A1 | P-sulphophenyl alkyl carbonates and their use as bleaching activators | Akzo Nobel N.V. (NL) | 1986-11-26 | — | — | EP | disclosed |