SCHEMBL4665656

SCHEMBL4665656

CCCCCCC(C)C(CCCCC)OC(CCCCC)C(C)CCCCCC

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.42
SMPD1 P17405 3/20 0.41
SPHK1 Q9NYA1 1/20 0.40
PTPN1 P18031 1/20 0.40
LMNA P02545 1/20 0.39
DNM1 Q05193 2/20 0.39
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
ADH1B P00325 1/20 0.38
ADH1C P00326 1/20 0.38
ADH1A P07327 1/20 0.38
ADH4 P08319 1/20 0.38
ADH7 P40394 1/20 0.38
ACE2 Q9BYF1 1/20 0.36
GPR84 Q9NQS5 2/20 0.35
FDPS P14324 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10781652 0.98 DNM1 (0.42) OPRM1SMPD1SPHK1PTPN1LMNA
SCHEMBL8221097 0.88 OPRM1 (0.41) OPRM1SMPD1SPHK1PTPN1LMNA
SCHEMBL8222305 0.88 OPRM1 (0.41) OPRM1SMPD1SPHK1PTPN1LMNA
SCHEMBL8861391 0.85 OPRM1 (0.38) OPRM1SMPD1SPHK1PTPN1LMNA
SCHEMBL1484239 0.85 OPRM1 (0.38) OPRM1SMPD1SPHK1PTPN1LMNA
SCHEMBL1482366 0.85 OPRM1 (0.38) OPRM1SMPD1SPHK1PTPN1LMNA
SCHEMBL8218897 0.85 OPRM1 (0.38) OPRM1SMPD1SPHK1PTPN1LMNA
SCHEMBL8210975 0.83 OPRM1 (0.44) OPRM1SMPD1SPHK1LMNADNM1
SCHEMBL2851672 0.83 OPRM1 (0.44) OPRM1SMPD1SPHK1LMNADNM1
SCHEMBL28693350 0.83 OPRM1 (0.44) OPRM1SMPD1SPHK1LMNADNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240382406-A1 PROCESS FOR TREATING KERATINOUS MATERIAL, COMPRISING THE MIXING OF AT LEAST TWO AGENTS (A) AND (B) HENKEL AG & CO. KGAA (DE) 2024-11-21 US disclosed
US-11285095-B2 Hair oils for conditioning keratin fibres HENKEL AG & CO. KGAA (DE) 2022-03-29 US disclosed
EP-3669858-A1 HAIR OILS FOR CONDITIONING KERATIN FIBRES Henkel AG & Co. KGaA (DE) 2020-06-24 EP disclosed
US-20200188287-A1 COSMETIC AGENTS FOR CONDITIONING KERATIN FIBRES HENKEL AG & CO. KGAA (DE) 2020-06-18 US disclosed
US-20200188284-A1 HAIR OILS FOR CONDITIONING KERATIN FIBRES HENKEL AG & CO. KGAA (DE) 2020-06-18 US disclosed
US-10639246-B2 Cleansing composition with high fatty acid content HENKEL AG & CO. KGAA (DE) 2020-05-05 US disclosed
US-20190192397-A1 HAIR OILS FOR CONDITIONING KERATIN FIBRES HENKEL AG & CO. KGAA (DE) 2019-06-27 US disclosed
EP-3310819-A1 COMPOSITION FOR IMMEDIATELY ENDING RADICAL POLYMERIZATION BASF SE (DE) 2018-04-25 EP disclosed
US-20170319876-A1 CONDITIONING HAIR CLEANSING AGENT HENKEL AG & CO, KGAA (DE) 2017-11-09 US disclosed
US-20170312191-A1 AGENTS AND METHODS FOR THE TEMPORARY SHAPING OF KERATIN-CONTAINING FIBERS HENKEL AG & CO. KGAA (DE) 2017-11-02 US disclosed
US-20080279794-A1 Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin BASCHONG WERNER 2008-11-13 US disclosed
US-20080260667-A1 Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin BASCHONG WERNER 2008-10-23 US disclosed
US-7147841-B2 Formulation of UV absorbers by incorporation in solid lipid nanoparticles CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-12-12 US disclosed
US-20060216252-A1 Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-09-28 US disclosed
EP-1648400-A1 USE OF HALOGENATED HYDROXYDIPHENYL ETHER COMPOUNDS FOR THE TREATMENT OF THE SKIN Ciba SC Holding AG (CH) 2006-04-26 EP disclosed
WO-2005013931-A1 USE OF HALOGENATED HYDROXYDIPHENYL ETHER COMPOUNDS FOR THE TREATMENT OF THE SKIN CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-02-17 WO disclosed
US-6730290-B2 MIXTURE CONTAINING WAX, EMULSIFIERS AND PROPELLANTS HANS SCHWARZKOPF GMBH & CO. KG (DE) 2004-05-04 US disclosed
EP-1378231-A1 Formulation of UV absorbers by incorporation in solid lipid nanoparticles Ciba Specialty Chemicals Holding Inc. (CH) 2004-01-07 EP disclosed
US-20030235540-A1 Formulation of UV absorbers by incorporation in solid lipid nanoparticles CIBA SPECIALTY CHEMICALS CORP. 2003-12-25 US disclosed
US-20030118516-A1 Aerosol spray HENKEL AG & CO. KGAA (DE) 2003-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030235540-A1 Formulation of UV absorbers by incorporation in solid lipid nanoparticles CUTA, LIPC, AUP1 OPRM1 3910/4885SMPD1 538/4885SPHK1 1325/4885
US-20190192397-A1 HAIR OILS FOR CONDITIONING KERATIN FIBRES KRT18, DSG1, CD74 OPRM1 4471/4885SMPD1 2878/4885SPHK1 1703/4885
US-20200188284-A1 HAIR OILS FOR CONDITIONING KERATIN FIBRES KRT18, HACD2, KAT8 OPRM1 2695/4885SMPD1 3101/4885SPHK1 1013/4885
US-20240382406-A1 PROCESS FOR TREATING KERATINOUS MATERIAL, COMPRISING THE MIXING OF AT LEAST TWO AGENTS (A) AND (B) KRT18, PHOSPHO1, DSG1 OPRM1 4629/4885SMPD1 1802/4885SPHK1 1409/4885
US-20170319876-A1 CONDITIONING HAIR CLEANSING AGENT DSG1, DSC1, CACNA1G OPRM1 4459/4885SMPD1 437/4885SPHK1 561/4885
US-11285095-B2 Hair oils for conditioning keratin fibres KRT18, HACD2, KAT8 OPRM1 2695/4885SMPD1 3101/4885SPHK1 1013/4885
US-20080260667-A1 Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin MC1R, TYR, MC3R OPRM1 1326/4885SMPD1 4475/4885SPHK1 1607/4885
US-20170312191-A1 AGENTS AND METHODS FOR THE TEMPORARY SHAPING OF KERATIN-CONTAINING FIBERS KRT18, CUTA, FLNA OPRM1 4869/4885SMPD1 1594/4885SPHK1 1719/4885
US-20080279794-A1 Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin MC1R, TYR, MC3R OPRM1 1326/4885SMPD1 4475/4885SPHK1 1607/4885
US-20060216252-A1 Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin MC1R, TYR, MC3R OPRM1 723/4885SMPD1 4414/4885SPHK1 1498/4885
US-10639246-B2 Cleansing composition with high fatty acid content H1-0, CUTA, PHOSPHO1 OPRM1 1453/4885SMPD1 237/4885SPHK1 1618/4885
US-20200188287-A1 COSMETIC AGENTS FOR CONDITIONING KERATIN FIBRES KRT18, TUBA8, TUBB8 OPRM1 3904/4885SMPD1 2178/4885SPHK1 2960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.