SCHEMBL472580

SCHEMBL472580

[O-][S+]1c2ccc(Cl)cc2Cc2cc(C(F)(F)F)ccc21

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.36
TDP2 O95551 1/20 0.35
TMPRSS4 Q9NRS4 2/20 0.34
MCL1 Q07820 1/20 0.34
P2RX1 P51575 1/20 0.34
P2RX4 Q99571 1/20 0.34
P2RX7 Q99572 1/20 0.34
CHRNA7 P36544 1/20 0.33
CYP19A1 P11511 1/20 0.33
KDM1A O60341 1/20 0.32
SLC6A4 P31645 1/20 0.32
MGLL Q99685 1/20 0.32
GRIK1 P39086 1/20 0.32
PNMT P11086 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6070128 0.85 AHR (0.37) AHRCYP19A1PNMT
SCHEMBL6860759 0.83 ALDH1A1 (0.37) TDP2PNMT
SCHEMBL13276514 0.78
SCHEMBL37076 0.77 CA1 (0.33) AHR
SCHEMBL11516655 0.77 CA1 (0.33) AHR
SCHEMBL11015531 0.73 ALDH1A1 (0.36)
SCHEMBL6070528 0.72 CYP1A2 (0.42) TDP2
SCHEMBL11661088 0.72 PGR (0.33) PNMT
SCHEMBL11751062 0.70 HTT (0.39) AHRCYP19A1SLC6A4PNMT
Anthraquinone SCHEMBL9789080 0.69 MAOA (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7678843-B2 Dental restorative material composition GC CORPORATION (JP) 2010-03-16 US claimed
EP-4029839-B1 GLASS POWDER AND CHEMICAL POLYMERIZATION INITIATOR G C DENTAL IND CORP (JP) 2026-05-06 EP disclosed
US-12600867-B2 Method of coating article, use for coating article, and polymerizable composition GC CORPORATION (JP) 2026-04-14 US disclosed
EP-3669854-B1 PHOTOPOLYMERIZABLE DENTAL COMPOSITION G C DENTAL IND CORP (JP) 2026-04-08 EP disclosed
US-12577340-B2 Storage stable two-component dual cure dental composition SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-17 US disclosed
US-12569409-B2 Dental polymerizable composition GC CORPORATION (JP) 2026-03-10 US disclosed
US-12497476-B2 Antibacterial polymer particles, composition, and article GC CORPORATION (JP) 2025-12-16 US disclosed
EP-4652982-A1 DENTAL RESTORATION MATERIAL COMPOSITION GC R&D Corporation (JP) 2025-11-26 EP disclosed
US-12478561-B2 Dental composition and dental restorative kit GC CORPORATION (JP) 2025-11-25 US disclosed
US-12460021-B2 Glass powder and chemical polymerization initiator GC CORPORATION (JP) 2025-11-04 US disclosed
US-5380772-A Modelling liquid for dental porcelain G-C TOSHI KOGYO CORPORATION (JP) 1995-01-10 US disclosed
US-5364890-A (meth)acrylate and a carbodiimide GC CORPORATION (JP) 1994-11-15 US disclosed
US-5356951-A (Meth)acrylate monomer; composite filler; glass powder; fine particle filler; photoinitiator; surface smoothness; less shrinkage GC CORPORATION (JP) 1994-10-18 US disclosed
US-5290172-A Method for preparing a tooth surface for bonding GC CORPORATION (JP) 1994-03-01 US disclosed
US-5063255-A (Meth)acrylates G-C TOSHI KOGYO CORPORATION (JP) 1991-11-05 US disclosed
US-5043361-A Photopolymerizable blend of unsaturated compound, photoinitiator, reducing agent, filler and peroxide G-C DENTAL INDUSTRIAL CORPORATION (JP) 1991-08-27 US disclosed
US-4843110-A BLEND CONTAINING A THIOXANTHONE PHOTOINITIATOR G-C DENTAL INDUSTRIAL CORPORATION (JP) 1989-06-27 US disclosed
US-4820744-A TWO PARTS-UNSATURATED COMPOUND, INITIATOR, AND REDUCING AGENT SEPARATED FROM ORGANIC PEROXIDE AND FILLER G-C DENTAL INDUSTRIAL CORP. (JP) 1989-04-11 US disclosed
US-4544467-A PHOSPHOROUS-CONTAINING UNSATURATED MONOMER , SULFUR COMPOUND AND PHOTOINITIATOR; BONDING STRENGTH MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-10-01 US disclosed
EP-0132318-A1 Light-curable dentin and enamel adhesive MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-01-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569409-B2 Dental polymerizable composition VCL, ACR, TPO AHR 4712/4885TDP2 462/4885TMPRSS4 4610/4885
US-12600867-B2 Method of coating article, use for coating article, and polymerizable composition SARS1, SPIN1, ESPL1 AHR 3630/4885TDP2 3128/4885TMPRSS4 2559/4885
US-12497476-B2 Antibacterial polymer particles, composition, and article PCNA, PARG, PUF60 AHR 3539/4885TDP2 3949/4885TMPRSS4 4088/4885
US-12577340-B2 Storage stable two-component dual cure dental composition GPX4, SSRP1, H1-0 AHR 3986/4885TDP2 1244/4885TMPRSS4 4441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.