Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 2/20 | 0.43 |
| ▸ | MPL | P40238 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.39 |
| ▸ | TST | Q16762 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | GLB1 | P16278 | 1/20 | 0.39 |
| ▸ | CHAT | P28329 | 1/20 | 0.39 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | ATIC | P31939 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790578 | 0.85 | CYP1A2 (0.64) | THRBCYP1A2CTRCMPLENPP2 | |
| SCHEMBL4759609 | 0.85 | CYP1A2 (0.64) | THRBCYP1A2CTRCMPLENPP2 | |
| SCHEMBL590710 | 0.81 | THRB (0.61) | THRBCYP1A2PTPN1DUSP5CTRC | |
| SCHEMBL29394629 | 0.77 | THRB (0.65) | THRBCYP1A2PTPN1DUSP5CTRC | |
| SCHEMBL2940832 | 0.76 | THRB (0.56) | THRBCYP1A2PTPN1CTRCENPP2 | |
| SCHEMBL29368745 | 0.74 | THRB (0.54) | THRBCYP1A2PTPN1DUSP5CTRC | |
| E122 SCHEMBL2833594 | 0.72 | THRB (1.00) | THRBCYP1A2PTPN1DUSP5CTRC | |
| E122 SCHEMBL29360316 | 0.72 | THRB (1.00) | THRBCYP1A2PTPN1DUSP5CTRC | |
| E122 SCHEMBL29360683 | 0.72 | THRB (1.00) | THRBCYP1A2PTPN1DUSP5CTRC | |
| E122 SCHEMBL42707 | 0.72 | THRB (1.00) | THRBCYP1A2PTPN1DUSP5CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080314409-A1 | METHOD FOR WASHING A GLASS CONTAINER | DIVERSEY, INC. (FORMERLY KNOWN AS JOHNSONDIVERSEY, INC.) | 2008-12-25 | — | — | US | claimed |
| WO-2007137250-A1 | A METHOD FOR WASHING A GLASS CONTAINER | JOHNSONDIVERSEY, INC. (US) | 2007-11-29 | — | — | WO | claimed |
| EP-1859873-A1 | Method and apparatus for washing a glass container | JohnsonDiversey, Inc. (US) | 2007-11-28 | — | — | EP | claimed |
| US-20080314409-A1 | METHOD FOR WASHING A GLASS CONTAINER | DIVERSEY, INC. (FORMERLY KNOWN AS JOHNSONDIVERSEY, INC.) | 2008-12-25 | — | — | US | disclosed |
| WO-2007137250-A1 | A METHOD FOR WASHING A GLASS CONTAINER | JOHNSONDIVERSEY, INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| EP-1859873-A1 | Method and apparatus for washing a glass container | JohnsonDiversey, Inc. (US) | 2007-11-28 | — | — | EP | disclosed |