Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | CTRC | Q99895 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | GLB1 | P16278 | 1/20 | 0.40 |
| ▸ | CHAT | P28329 | 1/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
| ▸ | TST | Q16762 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11757423 | 0.86 | THRB (0.56) | THRBCYP1A2NSD2MMP14CASP6 | |
| SCHEMBL11754648 | 0.86 | CYP1A2 (0.67) | THRBCYP1A2NSD2MMP14CASP6 | |
| SCHEMBL5148283 | 0.86 | CYP1A2 (0.67) | THRBCYP1A2NSD2MMP14CASP6 | |
| SCHEMBL4759611 | 0.81 | THRB (0.56) | THRBCYP1A2NSD2MMP14CASP6 | |
| SCHEMBL10898942 | 0.80 | NSD2 (0.63) | THRBCYP1A2NSD2MMP14CASP6 | |
| SCHEMBL29670503 | 0.79 | NSD2 (0.62) | THRBCYP1A2NSD2MMP14CASP6 | |
| SCHEMBL29394629 | 0.78 | THRB (0.65) | THRBCYP1A2PTPN1DUSP5ENPP2 | |
| SCHEMBL11760057 | 0.78 | NSD2 (0.76) | THRBCYP1A2NSD2MMP14CASP6 | |
| SCHEMBL2940832 | 0.77 | THRB (0.56) | THRBCYP1A2PTPN1ENPP2CTRC | |
| SCHEMBL10894104 | 0.76 | NSD2 (0.61) | THRBCYP1A2NSD2MMP14CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11884784-B2 | Photodynamic compositions, methods of making, and uses thereof | NORTH CAROLINA STATE UNIVERSITY (US) | 2024-01-30 | — | — | US | claimed |
| US-11696969-B2 | Ethylene oxide treatment indicator, label and method of use | Global Life Sciences Solutions Operations UK Ltd (GB) | 2023-07-11 | — | — | US | claimed |
| US-20190046678-A1 | Ethylene Oxide Treatment Indicator, Label and Method of Use | Global Life Sciences Solutions Operations UK Ltd (GB) | 2019-02-14 | — | — | US | claimed |
| EP-3423116-A1 | ETHYLENE OXIDE TREATMENT INDICATOR, LABEL AND METHOD OF USE | GE Healthcare UK Limited (GB) | 2019-01-09 | — | — | EP | claimed |
| WO-2006006969-A1 | TEXTILE INK COMPOSITION | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2006-01-19 | — | — | WO | claimed |
| US-20060000034-A1 | Textile ink composition | KIMBERLY-CLARK WORLDWIDE, INC. | 2006-01-05 | — | — | US | claimed |
| US-6531581-B1 | When incorporated into hairpin oligonucleotides these quench the fluorescence of fluorophores linked to the 5'-terminus of the oligonucleotide | SEROLOGICALS, INC. | 2003-03-11 | — | — | US | claimed |
| EP-1086115-A2 | PURINES AND PYRIMIDINES LINKED TO A QUENCHER | Intergen Company (US) | 2001-03-28 | — | — | EP | claimed |
| US-6117986-A | QUENCHING FLUORESCENCE | INTERGEN COMPANY, L.P. (US) | 2000-09-12 | — | — | US | claimed |
| WO-1999064431-A2 | PURINES AND PYRIMIDINES LINKED TO A QUENCHER | INTERGEN COMPANY (US) | 1999-12-16 | — | — | WO | claimed |
| US-4287481-A | Dye lasers | KLEINERMAN MARCOS | 1981-09-01 | — | — | US | claimed |
| US-20260015651-A1 | Solid Support for Sample Collection | Global Life Sciences Solutions Operations UK Ltd (GB) | 2026-01-15 | — | — | US | disclosed |
| US-20260009139-A1 | FORMATION OF CONVERSION COATING WITH ENHANCED ADHESION PROMOTION | HAMILTON SUNDSTRAND CORP (US) | 2026-01-08 | — | — | US | disclosed |
| EP-4667216-A1 | SHEET MATERIAL, PACKAGING CONTAINER, FLEXIBLE COMPOSITE AND METHOD FOR RECYCLING | Camm Solutions (Spain) R&D, S.l.u. (ES) | 2025-12-24 | — | — | EP | disclosed |
| US-12442032-B2 | Solid support for sample collection | Global Life Sciences Solutions Operations UK Ltd (GB) | 2025-10-14 | — | — | US | disclosed |
| US-5344489-A | Synthetic, monodispersed color pigments for the coloration of media such as printing inks, and method and apparatus for making same | Kuehnle, Manfred R. (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0612337-A1 | SYNTHETIC, MONODISPERSED COLOR PIGMENTS FOR THE COLORATION OF MEDIA SUCH AS PRINTING INKS, AND METHOD AND APPARATUS FOR MAKING SAME | KUEHNLE, Manfred R. (US) | 1994-08-31 | — | — | EP | disclosed |
| US-5318628-A | A paint particles comprising a core surrounding multilayer of opaque layer, a dye layer and a polymeric protective coatings | Kuehnle, Manfred R. (US) | 1994-06-07 | — | — | US | disclosed |
| WO-1993010190-A1 | SYNTHETIC, MONODISPERSED COLOR PIGMENTS FOR THE COLORATION OF MEDIA SUCH AS PRINTING INKS, AND METHOD AND APPARATUS FOR MAKING SAME | KUEHNLE MANFRED K (US) | 1993-05-27 | — | — | WO | disclosed |
| US-4287481-A | Dye lasers | KLEINERMAN MARCOS | 1981-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260009139-A1 | FORMATION OF CONVERSION COATING WITH ENHANCED ADHESION PROMOTION | ITGA1, ITGB1, YAP1 | THRB 2155/4885CYP1A2 2048/4885NSD2 2075/4885 |
| US-20260015651-A1 | Solid Support for Sample Collection | EWSR1, SETDB1, DNMT3A | THRB 1942/4885CYP1A2 3005/4885NSD2 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.