Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2729134 | 1.00 | TSHR (0.45) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL158736 | 1.00 | TSHR (0.45) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL401361 | 1.00 | TSHR (0.45) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL208566 | 1.00 | TSHR (0.45) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL5982864 | 1.00 | TSHR (0.45) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL4941637 | 1.00 | TSHR (0.45) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL11203648 | 1.00 | TSHR (0.45) | TSHRRECQLGLAHPGDMAPK1 | |
| Potassium Ion SCHEMBL8777175 | 0.97 | NAAA (0.42) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL2120646 | 0.92 | FABP3 (0.47) | EPHX2 | |
| SCHEMBL11128465 | 0.91 | RECQL (0.45) | TSHRRECQLGLAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188574-A1 | LIghtweight, clean feel; long lasting, sweat resistant sunscreen cosmetics; preparation with high speed bead mill; hydrophobic treatment | SUNJIN CHEMICAL CO., LTD. (KR) | 2008-08-07 | — | — | US | claimed |
| US-12458026-B2 | Pesticide compositions | SPECIALTY OPERATIONS FRANCE (FR) | 2025-11-04 | — | — | US | disclosed |
| CN-119968452-A | Perfume mixture (VI) | 西姆莱斯股份公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-119790128-A | Perfume mixture (III) | 西姆莱斯股份公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-119744164-A | Odor and colorant stable compositions | 西姆莱斯股份公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-119604270-A | Comprising an antimicrobial agent accelerator composition | 西姆莱斯股份公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-119486725-A | (2E) Mixtures and uses of (E) -3- (1, 3-benzodioxol-5-yl) -N-phenyl-N- (tetrahydro-3-furanyl) -2-propenamide | 西姆莱斯有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-119317695-A | Perfume mixture (V) | 西姆莱斯股份公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-119317696-A | Perfume mixture (V) | 西姆莱斯股份公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-119255980-A | Perfume with cyclopropyl structure | 西姆莱斯股份公司 | 2025-01-03 | — | — | CN | disclosed |
| EP-3648607-A1 | PESTICIDE COMPOSITIONS | Rhodia Operations (FR) | 2020-05-13 | — | — | EP | disclosed |
| US-20200128831-A1 | Pesticide Compositions | SPECIALTY OPERATIONS FRANCE (FR) | 2020-04-30 | — | — | US | disclosed |
| CN-111050742-A | Water-based concentrated product form of oil-soluble organic UV absorber | 巴斯夫欧洲公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-110582266-A | Improved cleaning compositions | 强生消费者公司 | 2019-12-17 | — | — | CN | disclosed |
| WO-2019006726-A1 | HERBICIDAL COMPOSITIONS | RHODIA OPERATIONS (FR) | 2019-01-10 | — | — | WO | disclosed |
| WO-2019007393-A1 | PESTICIDE COMPOSITIONS | RHODIA OPERATIONS (FR) | 2019-01-10 | — | — | WO | disclosed |
| US-20080188574-A1 | LIghtweight, clean feel; long lasting, sweat resistant sunscreen cosmetics; preparation with high speed bead mill; hydrophobic treatment | SUNJIN CHEMICAL CO., LTD. (KR) | 2008-08-07 | — | — | US | disclosed |
| US-5861365-A | FLUOROALKYL POLYOXYALKYLENE COMPOUND, A POLYACID OR AMINE, ANIONIC SURFACTANTS WITH SOLVENT, CITRIC ACID SALT AND WATER | RECKITT & COLMAN INC. (US) | 1999-01-19 | — | — | US | disclosed |
| EP-0472591-A1 | SULFOSUCCINATE DETERGENT COMPOSITION | HENKEL CORPORATION (US) | 1992-03-04 | — | — | EP | disclosed |
| WO-1990014411-A1 | SULFOSUCCINATE DETERGENT COMPOSITION | HENKEL CORPORATION (US) | 1990-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12458026-B2 | Pesticide compositions | DDT, SGMS2, SGMS1 | TSHR 2083/4885RECQL 2931/4885GLA 2320/4885 |
| US-20200128831-A1 | Pesticide Compositions | DDT, SGMS2, SGMS1 | TSHR 2083/4885RECQL 2931/4885GLA 2320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.