Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.47 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29391237 | 0.93 | FABP3 (0.43) | FABP3SLC6A5EPHX2 | |
| SCHEMBL4941637 | 0.92 | TSHR (0.45) | EPHX2 | |
| SCHEMBL5982864 | 0.92 | TSHR (0.45) | EPHX2 | |
| SCHEMBL11203648 | 0.92 | TSHR (0.45) | EPHX2 | |
| SCHEMBL4809983 | 0.92 | TSHR (0.45) | EPHX2 | |
| SCHEMBL401361 | 0.92 | TSHR (0.45) | EPHX2 | |
| SCHEMBL2729134 | 0.92 | TSHR (0.45) | EPHX2 | |
| SCHEMBL208566 | 0.92 | TSHR (0.45) | EPHX2 | |
| SCHEMBL158736 | 0.92 | TSHR (0.45) | EPHX2 | |
| SCHEMBL23064683 | 0.91 | FABP3 (0.48) | FABP3FAAHSLC6A5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080299065-A1 | COMPOSITION CONTAINING SULFONIC ACID AND/OR SULFURIC ACID COMPOUND | L'OREAL (FR) | 2008-12-04 | — | — | US | claimed |
| US-20080188574-A1 | LIghtweight, clean feel; long lasting, sweat resistant sunscreen cosmetics; preparation with high speed bead mill; hydrophobic treatment | SUNJIN CHEMICAL CO., LTD. (KR) | 2008-08-07 | — | — | US | claimed |
| EP-1920799-A1 | Cosmetic composition comprising a derivative of sulfonic acid or a derivative of sulfuric acid | L'Oréal (FR) | 2008-05-14 | — | — | EP | claimed |
| US-12629327-B2 | Keratin-based hair straightening formulations, methods and systems | BEAUTY BIOLABS LLC (US) | 2026-05-19 | — | — | US | disclosed |
| CN-119997951-A | Method for preventing, alleviating and/or treating PTGS 2-induced skin disorders and related dysfunctions | 西姆莱斯股份公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-114728092-B | Edge block with improved odor performance | 西姆莱斯股份公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119486725-A | (2E) Mixtures and uses of (E) -3- (1, 3-benzodioxol-5-yl) -N-phenyl-N- (tetrahydro-3-furanyl) -2-propenamide | 西姆莱斯有限公司 | 2025-02-18 | — | — | CN | disclosed |
| US-20240409779-A1 | MOISTURE CURABLE ADHESIVE COMPOSITION | ARKEMA FRANCE (FR) | 2024-12-12 | — | — | US | disclosed |
| US-20240390258-A1 | FOAMING COMPOSITION | L'OREAL (FR) | 2024-11-28 | — | — | US | disclosed |
| CN-118922168-A | Sun cream additive | 西姆莱斯股份公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-118891030-A | Hair care compositions | 西姆莱斯股份公司 | 2024-11-01 | — | — | CN | disclosed |
| US-20090165812-A1 | HAIR STRAIGHTENING FORMULATIONS, METHODS AND SYSTEMS | LIQUID KERATIN, INC. (CA) | 2009-07-02 | — | — | US | disclosed |
| US-20090104430-A1 | LATHER-FORMING TISSUE PAPER PRODUCT | SCA HYGIENE PRODUCTS AB (SE) | 2009-04-23 | — | — | US | disclosed |
| US-20090081755-A1 | FRAGRANT CONSUMER PRODUCTS COMPRISING OXIDIZING AGENTS | HENKEL AG & CO. KG A (DE) | 2009-03-26 | — | — | US | disclosed |
| WO-2009035970-A1 | HAIR STRAIGHTENING FORMULATIONS, METHODS AND SYSTEMS | RESNICK LIONEL (US) | 2009-03-19 | — | — | WO | disclosed |
| EP-2002058-A1 | LATHER-FORMING TISSUE PAPER PRODUCT | SCA Hygiene Products GmbH (DE) | 2008-12-17 | — | — | EP | disclosed |
| US-20080299065-A1 | COMPOSITION CONTAINING SULFONIC ACID AND/OR SULFURIC ACID COMPOUND | L'OREAL (FR) | 2008-12-04 | — | — | US | disclosed |
| US-20080188574-A1 | LIghtweight, clean feel; long lasting, sweat resistant sunscreen cosmetics; preparation with high speed bead mill; hydrophobic treatment | SUNJIN CHEMICAL CO., LTD. (KR) | 2008-08-07 | — | — | US | disclosed |
| EP-1920799-A1 | Cosmetic composition comprising a derivative of sulfonic acid or a derivative of sulfuric acid | L'Oréal (FR) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007112916-A1 | LATHER-FORMING TISSUE PAPER PRODUCT | SCA HYGIENE PRODUCTS GMBH (DE) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12629327-B2 | Keratin-based hair straightening formulations, methods and systems | KRT18, HCN4, COL14A1 | FABP3 3240/4885FAAH 3621/4885SLC6A5 443/4885 |
| US-20240390258-A1 | FOAMING COMPOSITION | SGMS1, SGMS2, SMURF1 | FABP3 440/4885FAAH 164/4885SLC6A5 1484/4885 |
| US-20080299065-A1 | COMPOSITION CONTAINING SULFONIC ACID AND/OR SULFURIC ACID COMPOUND | STS, MPST, TST | FABP3 634/4885FAAH 342/4885SLC6A5 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.