Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.38 |
| ▸ | CA12 known ✓ | O43570 | 4/20 | 0.35 |
| ▸ | CA1 known ✓ | P00915 | 4/20 | 0.35 |
| ▸ | CA2 known ✓ | P00918 | 4/20 | 0.35 |
| ▸ | P2RY4 known ✓ | P51582 | 3/20 | 0.34 |
| ▸ | P2RY2 known ✓ | P41231 | 2/20 | 0.33 |
| ▸ | P2RY6 known ✓ | Q15077 | 2/20 | 0.33 |
| ▸ | P2RY12 known ✓ | Q9H244 | 2/20 | 0.33 |
| ▸ | P2RY1 known ✓ | P47900 | 1/20 | 0.32 |
| ▸ | FUT8 | Q9BYC5 | 2/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GRK2 | P25098 | 1/20 | 0.38 |
| ▸ | PLEC | Q15149 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4849250 | 0.94 | ENPP2 (0.41) | FUT8PRMT1CARM1ENPP2APP | |
| SCHEMBL4855331 | 0.91 | FUT8 (0.59) | FUT8PRMT1CARM1ENPP2MEN1 | |
| SCHEMBL4855317 | 0.90 | FUT8 (0.58) | FUT8PRMT1CARM1ENPP2MEN1 | |
| SCHEMBL4849257 | 0.85 | FUT8 (0.51) | FUT8PRMT1ENPP2MEN1KMT2A | |
| SCHEMBL14255277 | 0.85 | FUT8 (0.51) | FUT8PRMT1ENPP2MEN1KMT2A | |
| SCHEMBL4849237 | 0.84 | FUT8 (0.50) | FUT8PRMT1ENPP2MEN1KMT2A | |
| SCHEMBL29385758 | 0.84 | FUT8 (0.56) | FUT8PRMT1CARM1ENPP2APP | |
| SCHEMBL6808069 | 0.84 | FUT8 (0.56) | FUT8PRMT1CARM1ENPP2APP | |
| SCHEMBL29405634 | 0.78 | PRMT1 (0.53) | FUT8PRMT1CARM1ENPP2APP | |
| SCHEMBL29663889 | 0.76 | FUT8 (0.67) | FUT8PRMT1CARM1ENPP2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7341604-B2 | Highly affine cosmetic agent | WELLA AG (DE) | 2008-03-11 | — | — | US | disclosed |
| US-20060174423-A1 | Highly affine cosmetic agent | Wella GmbH (DE) | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060174423-A1 | Highly affine cosmetic agent | TYR, ENO1, CUTA | THRB 3853/4885CA12 2216/4885CA1 3100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.