Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 2/20 | 0.47 |
| ▸ | FPR1 | P21462 | 1/20 | 0.47 |
| ▸ | GPR183 | P32249 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | PTAFR | P25105 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4852148 | 0.94 | GNRHR (0.46) | GNRHRFPR1GPR183GPR119S1PR4 | |
| SCHEMBL6667029 | 0.90 | GNRHR (0.47) | GNRHRFPR1GPR183GPR119S1PR4 | |
| SCHEMBL4852225 | 0.85 | S1PR4 (0.43) | GNRHRFPR1GPR183GPR119S1PR4 | |
| SCHEMBL4862829 | 0.84 | GNRHR (0.46) | GNRHRFPR1GPR183GPR119S1PR4 | |
| SCHEMBL6639154 | 0.84 | GNRHR (0.47) | GNRHRFPR1GPR183GPR119S1PR4 | |
| SCHEMBL4863755 | 0.82 | GNRHR (0.48) | GNRHRFPR1GPR183GPR119S1PR4 | |
| SCHEMBL6645028 | 0.82 | FPR1 (0.48) | GNRHRFPR1GPR183GPR119S1PR4 | |
| SCHEMBL6666402 | 0.81 | S1PR4 (0.44) | GNRHRFPR1GPR183GPR119S1PR4 | |
| SCHEMBL4863039 | 0.80 | GNRHR (0.50) | GNRHRFPR1GPR183GPR119S1PR4 | |
| SCHEMBL6669991 | 0.80 | GNRHR (0.48) | GNRHRFPR1GPR183GPR119S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015061485-A1 | NAIL COATINGS INCLUDING FATTY ACID ESTERS | CREATIVE NAIL DESIGN, INC. (US) | 2015-04-30 | — | — | WO | claimed |
| US-7407649-B2 | Compounds having a benzene ring substituted with 1 or 2 trialkylsilyl(alkyl) groups and at least 2 additional aryl or heteroaryl rings: 5-[2-methyl-5-(trimethylsilyl)phenoxy]-N-(2,6-dimethoxyphenyl)furan-2-carboxamide; Gonadotropin-Releasing Hormone antagonists; anticancer agents | PARADIGM THERAPEUTICS LTD (GB) | 2008-08-05 | — | — | US | claimed |
| EP-1644385-B1 | SILICON COMPOUNDS AND THEIR USE | TAKEDA CAMBRIDGE LTD (GB) | 2007-08-29 | — | — | EP | claimed |
| US-20070110708-A1 | Silicon compounds and their use | PARADIGM THERAPEUTICS LTD (GB) | 2007-05-17 | — | — | US | claimed |
| US-9713585-B2 | Nail coatings having enhanced adhesion | CREATIVE NAIL DESIGN, INC. (US) | 2017-07-25 | — | — | US | disclosed |
| US-20170056313-A1 | NAIL COATINGS HAVING ENHANCED ADHESION | CREATIVE NAIL DESIGN, INC. (US) | 2017-03-02 | — | — | US | disclosed |
| US-20160067164-A1 | NAIL COATINGS HAVING ENHANCED ADHESION | MUFG BANK LTD. AS AGENT | 2016-03-10 | — | — | US | disclosed |
| EP-2988721-A1 | NAIL COATINGS HAVING ENHANCED ADHESION | Creative Nail Design, Inc. (US) | 2016-03-02 | — | — | EP | disclosed |
| WO-2015061485-A1 | NAIL COATINGS INCLUDING FATTY ACID ESTERS | CREATIVE NAIL DESIGN, INC. (US) | 2015-04-30 | — | — | WO | disclosed |
| WO-2014176275-A1 | NAIL COATINGS HAVING ENHANCED ADHESION | CREATIVE NAIL DESIGN, INC. (US) | 2014-10-30 | — | — | WO | disclosed |
| US-20140053859-A1 | NAIL COATINGS AND METHODS THEREOF | CREATIVE NAIL DESIGN, INC. (US) | 2014-02-27 | — | — | US | disclosed |
| WO-2014031184-A2 | NAIL COATINGS AND METHODS THEREOF | CREATIVE NAIL DESIGN, INC. (US) | 2014-02-27 | — | — | WO | disclosed |
| US-7407649-B2 | Compounds having a benzene ring substituted with 1 or 2 trialkylsilyl(alkyl) groups and at least 2 additional aryl or heteroaryl rings: 5-[2-methyl-5-(trimethylsilyl)phenoxy]-N-(2,6-dimethoxyphenyl)furan-2-carboxamide; Gonadotropin-Releasing Hormone antagonists; anticancer agents | PARADIGM THERAPEUTICS LTD (GB) | 2008-08-05 | — | — | US | disclosed |
| US-20080081022-A1 | Poss Containing Cosmetic Compositions Having Improved Wear And/Or Pliability And Methods Of Making Improved Cosmetic Compositions | L'OREAL (FR) | 2008-04-03 | — | — | US | disclosed |
| EP-1644385-B1 | SILICON COMPOUNDS AND THEIR USE | TAKEDA CAMBRIDGE LTD (GB) | 2007-08-29 | — | — | EP | disclosed |
| EP-1794233-A1 | POSS CONTAINING COSMETIC COMPOSITIONS HAVING IMPROVED WEAR AND/OR PLIABILITY AND METHODS OF MAKING IMPROVED COSMETIC COMPOSITIONS | L'OREAL (FR) | 2007-06-13 | — | — | EP | disclosed |
| US-20070110708-A1 | Silicon compounds and their use | PARADIGM THERAPEUTICS LTD (GB) | 2007-05-17 | — | — | US | disclosed |
| US-20070110708-A1 | Silicon compounds and their use | PARADIGM THERAPEUTICS LTD (GB) | 2007-05-17 | — | — | US | disclosed |
| WO-2006031781-A1 | POSS CONTAINING COSMETIC COMPOSITIONS HAVING IMPROVED WEAR AND/OR PLIABILITY AND METHODS OF MAKING IMPROVED COSMETIC COMPOSITIONS | L'OREAL (FR) | 2006-03-23 | — | — | WO | disclosed |
| US-20040202623-A1 | POSS containing cosmetics and personal care products | L'OREAL S.A. (FR) | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070110708-A1 | Silicon compounds and their use | SOST, SMAD3, SMAD2 | GNRHR 1621/4885FPR1 3685/4885GPR183 4141/4885 |
| US-20160067164-A1 | NAIL COATINGS HAVING ENHANCED ADHESION | PIK3C3, POLR1C, NACA | GNRHR 4820/4885FPR1 2047/4885GPR183 3856/4885 |
| US-20080081022-A1 | Poss Containing Cosmetic Compositions Having Improved Wear And/Or Pliability And Methods Of Making Improved Cosmetic Compositions | PLOD3, LAGE3, CUTA | GNRHR 1623/4885FPR1 2481/4885GPR183 2505/4885 |
| US-20140053859-A1 | NAIL COATINGS AND METHODS THEREOF | NACA, DPM1, POLR1C | GNRHR 4400/4885FPR1 2323/4885GPR183 4544/4885 |
| US-20040202623-A1 | POSS containing cosmetics and personal care products | SCLY, LAGE3, POLR1C | GNRHR 1566/4885FPR1 3562/4885GPR183 738/4885 |
| US-20170056313-A1 | NAIL COATINGS HAVING ENHANCED ADHESION | POLR1C, PIK3C3, NACA | GNRHR 4864/4885FPR1 2156/4885GPR183 3896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.