Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 5/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4870207 | 0.98 | METAP1 (0.36) | METAP1CCR6MITFHSP90AA1 | |
| SCHEMBL3327529 | 0.78 | — | — | |
| SCHEMBL14169479 | 0.74 | NOS1 (0.38) | — | |
| SCHEMBL14635516 | 0.74 | — | — | |
| SCHEMBL3325656 | 0.73 | PDK1 (0.32) | — | |
| SCHEMBL13899831 | 0.73 | — | — | |
| SCHEMBL358873 | 0.72 | TLR4 (0.33) | — | |
| SCHEMBL3024107 | 0.71 | MT-CO2 (0.37) | HSP90AA1 | |
| SCHEMBL14101011 | 0.71 | NOS2 (0.30) | — | |
| SCHEMBL8554107 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3750883-B1 | AMINOALKYL COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2023-10-04 | — | — | EP | disclosed |
| CN-111655675-B | Aminoalkyl compounds | 第一三共株式会社 | 2023-09-22 | — | — | CN | disclosed |
| US-11440896-B2 | Aminoalkyl compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2022-09-13 | — | — | US | disclosed |
| US-20210040057-A1 | AMINOALKYL COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-02-11 | — | — | US | disclosed |
| EP-3750883-A1 | AMINOALKYL COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2020-12-16 | — | — | EP | disclosed |
| US-7384961-B2 | Saturated and unsaturated heteroarylcycloalkylmethyl amines as anti-depressants | GRUENENTHAL GMBH (DE) | 2008-06-10 | — | — | US | disclosed |
| EP-1572653-B1 | SATURATED AND UNSATURATED HETEROARYLCYCLOALKYLMETHYL AMINES AS ANTI-DEPRESSANTS | GRUENENTHAL GMBH (DE) | 2007-11-21 | — | — | EP | disclosed |
| US-20060025456-A1 | Saturated and unsaturated heteroarylcycloalkylmethyl amines as anti-depressants | GRUENENTHAL GMBH (DE) | 2006-02-02 | — | — | US | disclosed |
| EP-1572653-A1 | SATURATED AND UNSATURATED HETEROARYLCYCLOALKYLMETHYL AMINES AS ANTI-DEPRESSANTS | Grünenthal GmbH (DE) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004063161-A1 | SATURATED AND UNSATURATED HETEROARYLCYCLOALKYLMETHYL AMINES AS ANTI-DEPRESSANTS | Grünenthal GmbH (DE) | 2004-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040057-A1 | AMINOALKYL COMPOUND | TRPA1, TRPV1, TRPV5 | METAP1 661/4885CCR6 791/4885MITF 1708/4885 |
| US-20060025456-A1 | Saturated and unsaturated heteroarylcycloalkylmethyl amines as anti-depressants | OPRK1, OPRM1, HTR1A | METAP1 3260/4885CCR6 4184/4885MITF 1534/4885 |
| US-11440896-B2 | Aminoalkyl compound | TRPA1, TRPV1, TRPV5 | METAP1 661/4885CCR6 791/4885MITF 1708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.