SCHEMBL5016277

SCHEMBL5016277

COc1cc2c(c(OC)c1OC)CNCC2

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 8/20 0.49
HTR2C P28335 8/20 0.49
HTR2B P41595 8/20 0.49
PNMT P11086 2/20 0.48
LMNA P02545 2/20 0.47
POLB P06746 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ATM Q13315 1/20 0.45
ALDH1A1 P00352 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29396030 0.85 CCNB2 (0.46) HTR2AHTR2CHTR2BPNMTLMNA
SCHEMBL675760 0.85 CCNB2 (0.46) HTR2AHTR2CHTR2BPNMTLMNA
SCHEMBL10792005 0.84 NQO2 (0.45) LMNAPOLBTDP1ATMALDH1A1
SCHEMBL28340616 0.79 DYRK1A (0.46) HTR2CHTR2BPNMT
SCHEMBL5022472 0.79 PNMT (0.59) HTR2AHTR2CHTR2BPNMTALDH1A1
SCHEMBL6223597 0.77 HTR2A (0.50) HTR2AHTR2CHTR2BLMNAPOLB
SCHEMBL11162952 0.77 HTR2C (0.58) HTR2AHTR2CHTR2BLMNAATM
SCHEMBL13365442 0.77 ADCY6 (0.44) PNMT
SCHEMBL3882991 0.76 PNMT (0.48) HTR2AHTR2CHTR2BPNMTLMNA
SCHEMBL329913 0.76 HTR2A (0.61) HTR2AHTR2CHTR2BPNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260053878-A1 PROCESS FOR EXTRACTION OF ACTIVE COMPOUNDS FROM PLANT BIOMASS NEURAL THERAPEUTICS INC (CA) 2026-02-26 US disclosed
US-12551519-B2 Extraction system and method for organic metabolites VCENNA TECH & LABS INC (CA) 2026-02-17 US disclosed
US-20250339631-A1 CONTROLLED RELEASE OF SUBSTANCES FROM A SOURCE MATERIAL STORED OVER TIME SYQE MEDICAL LTD. (IL) 2025-11-06 US disclosed
US-20250162980-A1 METHODS FOR PREPARING MESCALINE JOURNEY COLAB CORP. 2025-05-22 US disclosed
US-20250157614-A1 SUBSTANCE DELIVERY PLANNING SYSTEM SYQE MEDICAL LTD. (IL) 2025-05-15 US disclosed
EP-4504308-A1 CONTROLLED RELEASE OF SUBSTANCES FROM A SOURCE MATERIAL STORED OVER TIME Syqe Medical Ltd. (IL) 2025-02-12 EP disclosed
US-20240245632-A1 METHODS OF TREATING SUBSTANCE USE DISORDERS USING MESCALINE JOURNEY COLAB CORP. 2024-07-25 US disclosed
US-20240123005-A1 EXTRACTION SYSTEM AND METHOD FOR ORGANIC METABOLITES Etminan, Seyed Reza (CA) 2024-04-18 US disclosed
US-20240108577-A1 CONTROLLED RELEASE OF SUBSTANCES FROM A SOURCE MATERIAL SYQE MEDICAL LTD. (IL) 2024-04-04 US disclosed
WO-2024040358-A1 PROCESS FOR EXTRACTION OF ACTIVE COMPOUNDS FROM PLANT BIOMASS NEURAL THERAPEUTICS INC. (CA) 2024-02-29 WO disclosed
EP-0569380-B1 ACRIDINE DERIVATIVES GLAXO LAB SA (FR) 1997-05-28 EP disclosed
US-5604237-A IMPROVE OR INCREASE EFFICACY OF ANTITUMOR AGENT, INCREASE OR RESTORE SENSITIVITY OF TUMOR TO ANTITUMOR AGENT, REVERSE OR REDUCE RESISTANCE OF TUMOR TO ANTITUMOR AGENT LABORATOIRES GLAXO SA (FR) 1997-02-18 US disclosed
US-5561141-A POTENTIATE ACTIVITY OF ANTITUMOR AGENTS AMERICAN CYANAMID COMPANY (US) 1996-10-01 US disclosed
US-5550149-A SULFUR-CONTAINING COMPOUNDS THAT ARE EFFECTIVE IN POTENTIATING THE ACTIVITY OF CHEMOTHERAPEUTIC ANTI-CANCER AGENTS BY INCREASING SENSITIVITY OF MULTI-DRUG RESISTANT CELLS AMERICAN CYANAMID COMPANY (US) 1996-08-27 US disclosed
CN-1114650-A MDR reversal agents AMERICAN CYANAMID CO (US) 1996-01-10 CN disclosed
US-5387685-A MDR reversal agents AMERICAN CYANAMID COMPANY 1995-02-07 US disclosed
EP-0634401-A1 MDR reversal agents AMERICAN CYANAMID COMPANY (US) 1995-01-18 EP disclosed
EP-0569380-A1 ACRIDINE DERIVATIVES. GLAXO LAB SA (FR) 1993-11-18 EP disclosed
WO-1992012132-A1 ACRIDINE DERIVATIVES LABORATOIRES GLAXO S.A. (FR) 1992-07-23 WO disclosed
EP-0494623-A1 Acridine derivatives LABORATOIRES GLAXO SA (FR) 1992-07-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260053878-A1 PROCESS FOR EXTRACTION OF ACTIVE COMPOUNDS FROM PLANT BIOMASS CARM1, CLK4, NPM1 HTR2A 4528/4885HTR2C 4575/4885HTR2B 4689/4885
US-20240245632-A1 METHODS OF TREATING SUBSTANCE USE DISORDERS USING MESCALINE SLC6A12, SLC6A3, TPMT HTR2A 93/4885HTR2C 24/4885HTR2B 246/4885
US-20250162980-A1 METHODS FOR PREPARING MESCALINE IL4I1, ME3, LIG3 HTR2A 3249/4885HTR2C 2131/4885HTR2B 2009/4885
US-12551519-B2 Extraction system and method for organic metabolites SHH, WNT1, WNT3A HTR2A 319/4885HTR2C 42/4885HTR2B 516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.