SCHEMBL675760

SCHEMBL675760

COc1cc2c(c(O)c1OC)CNCC2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNB2 O95067 1/20 0.46
CDK1 P06493 1/20 0.46
CCNB1 P14635 1/20 0.46
CCNB3 Q8WWL7 1/20 0.46
ATM Q13315 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
HTR2A P28223 2/20 0.45
HTR2C P28335 2/20 0.45
HTR2B P41595 2/20 0.45
PNMT P11086 2/20 0.44
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
KMT2A Q03164 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
HTR1A P08908 1/20 0.39
ADRA2A P08913 1/20 0.39
ADRB3 P13945 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29396030 1.00 CCNB2 (0.46) CCNB2CDK1CCNB1CCNB3ATM
SCHEMBL5016277 0.85 HTR2A (0.49) ATMTDP1HTR2AHTR2CHTR2B
SCHEMBL13365442 0.79 ADCY6 (0.44) PNMTTBXA2R
SCHEMBL16210119 0.78 PNMT (0.57) HTR2AHTR2CHTR2BPNMTADRA2A
SCHEMBL28340616 0.76 DYRK1A (0.46) HTR2CHTR2BPNMTADRB2ADRB1
SCHEMBL18860287 0.75 PNMT (0.48) HTR2AHTR2CHTR2BPNMTALDH1A1
SCHEMBL11162952 0.73 HTR2C (0.58) ATMHTR2AHTR2CHTR2BALDH1A1
SCHEMBL6223597 0.73 HTR2A (0.50) ATMTDP1HTR2AHTR2CHTR2B
SCHEMBL11820769 0.73 PNMT (0.49) HTR2AHTR2CHTR2BPNMTADRB2
SCHEMBL3882991 0.72 PNMT (0.48) HTR2AHTR2CHTR2BPNMTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023121486-A1 COMPOSITIONS AND COMPOUNDS FOR TREATING COVID-19 INTERNATIONAL PATENT HOLDINGS LLC (KN) 2023-06-29 WO claimed
US-8067401-B2 Compounds and compositions for treating infection INTERNATIONAL PATENT HOLDINGS LLC (KN) 2011-11-29 US claimed
US-20090069277-A1 Compounds and compositions for treating infection INTERNATIONAL PATENT HOLDINGS LTD. 2009-03-12 US claimed
US-20260053878-A1 PROCESS FOR EXTRACTION OF ACTIVE COMPOUNDS FROM PLANT BIOMASS NEURAL THERAPEUTICS INC (CA) 2026-02-26 US disclosed
US-12551519-B2 Extraction system and method for organic metabolites VCENNA TECH & LABS INC (CA) 2026-02-17 US disclosed
US-20250162980-A1 METHODS FOR PREPARING MESCALINE JOURNEY COLAB CORP. 2025-05-22 US disclosed
WO-2024246905-A1 ENZYMES, POLYNUCLEOTIDES ENCODING SAME, AND METHODS OF USING SAME FOR PRODUCING MESCALINE YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2024-12-05 WO disclosed
US-20240245632-A1 METHODS OF TREATING SUBSTANCE USE DISORDERS USING MESCALINE JOURNEY COLAB CORP. 2024-07-25 US disclosed
US-20240123005-A1 EXTRACTION SYSTEM AND METHOD FOR ORGANIC METABOLITES Etminan, Seyed Reza (CA) 2024-04-18 US disclosed
WO-2024040358-A1 PROCESS FOR EXTRACTION OF ACTIVE COMPOUNDS FROM PLANT BIOMASS NEURAL THERAPEUTICS INC. (CA) 2024-02-29 WO disclosed
CN-115785753-B Bamboo charcoal negative ion coating and preparation method and application thereof 亚士漆(上海)有限公司 2024-01-19 CN disclosed
US-8067401-B2 Compounds and compositions for treating infection INTERNATIONAL PATENT HOLDINGS LLC (KN) 2011-11-29 US disclosed
US-20090069277-A1 Compounds and compositions for treating infection INTERNATIONAL PATENT HOLDINGS LTD. 2009-03-12 US disclosed
US-20090069277-A1 Compounds and compositions for treating infection INTERNATIONAL PATENT HOLDINGS LTD. 2009-03-12 US disclosed
US-20090069277-A1 Compounds and compositions for treating infection INTERNATIONAL PATENT HOLDINGS LTD. 2009-03-12 US disclosed
EP-0617022-B1 6,7, dialkoxy-3,4-dihydroisoquinolin-8-ol, process for preparation thereof and process for preparation of 6,7-dialkoxy-1,2,3,4-tetrahydroisoquinolin-8-ol using the compound BANYU PHARMA CO LTD (JP) 1998-02-11 EP disclosed
US-5498717-A CHEMICAL INTERMEDIATES FOR PRODUCING ANTITUMOR POTENTIATORS BANYU PHARMACEUTICAL CO., LTD. (JP) 1996-03-12 US disclosed
US-5446164-A Regioselective cyclization of phenethylamide derivative in presence of phosphoric acid halide, reducing formed compound BANYU PHARMACEUTICAL CO., LTD. (JP) 1995-08-29 US disclosed
EP-0617022-A1 6,7, dialkoxy-3,4-dihydroisoquinolin-8-ol, process for preparation thereof and process for preparation of 6,7-dialkoxy-1,2,3,4-tetrahydroisoquinolin-8-ol using the compound BANYU PHARMACEUTICAL CO., LTD. (JP) 1994-09-28 EP disclosed
EP-0443533-A2 Positive photoresist composition FUJI PHOTO FILM CO., LTD. (JP) 1991-08-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260053878-A1 PROCESS FOR EXTRACTION OF ACTIVE COMPOUNDS FROM PLANT BIOMASS CARM1, CLK4, NPM1 CCNB2 212/4885CDK1 1369/4885CCNB1 406/4885
US-20090069277-A1 Compounds and compositions for treating infection RPN2, LSS, CLIC4 CCNB2 3527/4885CDK1 4223/4885CCNB1 4357/4885
US-20240245632-A1 METHODS OF TREATING SUBSTANCE USE DISORDERS USING MESCALINE SLC6A12, SLC6A3, TPMT CCNB2 2642/4885CDK1 3936/4885CCNB1 2819/4885
US-20250162980-A1 METHODS FOR PREPARING MESCALINE IL4I1, ME3, LIG3 CCNB2 994/4885CDK1 705/4885CCNB1 1125/4885
US-12551519-B2 Extraction system and method for organic metabolites SHH, WNT1, WNT3A CCNB2 732/4885CDK1 180/4885CCNB1 1383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.