Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24141587 | 0.88 | MEN1 (0.42) | FAAHMGLLCYP19A1CA1CA2 | |
| SCHEMBL1825898 | 0.84 | FAAH (0.50) | FAAHMGLLCYP19A1ATAD2CHRM2 | |
| 2-Pyrrolidone SCHEMBL28882175 | 0.83 | OR51E2 (0.46) | FAAHMGLLCYP19A1POLB | |
| SCHEMBL509098 | 0.82 | — | — | |
| SCHEMBL15468560 | 0.78 | CA1 (0.36) | ATAD2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL18719615 | 0.78 | PARK7 (0.33) | FAAHMGLLCA1CA2CA9 | |
| SCHEMBL14527918 | 0.76 | SMN1; SMN2 (0.34) | MEN1KMT2A | |
| SCHEMBL19048924 | 0.75 | CA1 (0.31) | CA1CA2CA9CA4 | |
| SCHEMBL718815 | 0.75 | MEN1 (0.53) | FAAHMGLLCYP19A1CHRM2CHRM4 | |
| SCHEMBL29211489 | 0.74 | FAAH (0.40) | FAAHMGLLCYP19A1ATAD2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1095 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12638614-B2 | Method for making silicone hydrogel contact lenses | ALCON INC. (CH) | 2026-05-26 | — | — | US | claimed |
| US-20260131506-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2026-05-14 | — | — | US | claimed |
| US-20260132236-A1 | LIGHT ABSORBERS FOR OPHTHALMC LENS MATERALS AND DEVICES | ALCON INC (CH) | 2026-05-14 | — | — | US | claimed |
| US-12595368-B2 | UV/HEVL-filtering contact lenses | ALCON INC. (CH) | 2026-04-07 | — | — | US | claimed |
| EP-4713721-A1 | UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2026-03-25 | — | — | EP | claimed |
| US-12570784-B2 | Method for making embedded hydrogel contact lenses | ALCON INC. (CH) | 2026-03-10 | — | — | US | claimed |
| EP-3759528-B1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2026-03-04 | — | — | EP | claimed |
| EP-4514596-B1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2026-03-04 | — | — | EP | claimed |
| US-20260042269-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC (CH) | 2026-02-12 | — | — | US | claimed |
| US-20260042268-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC (CH) | 2026-02-12 | — | — | US | claimed |
| US-20120029111-A1 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | ALCON INC. (CH) | 2012-02-02 | — | — | US | claimed |
| WO-2012016097-A2 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | NOVARTIS AG (CH) | 2012-02-02 | — | — | WO | claimed |
| WO-2011075377-A1 | METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | claimed |
| WO-2011071790-A1 | METHODS FOR INCREASING THE ION PERMEABILITY OF CONTACT LENSES | NOVARTIS AG (CH) | 2011-06-16 | — | — | WO | claimed |
| US-20110140292-A1 | METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS | ALCON INC. (CH) | 2011-06-16 | — | — | US | claimed |
| US-20110133350-A1 | METHODS FOR INCREASING THE ION PERMEABILITY OF CONTACT LENSES | ALCON INC. (CH) | 2011-06-09 | — | — | US | claimed |
| WO-2011056761-A1 | A SILICONE HYDROGEL LENS WITH A GRAFTED HYDROPHILIC COATING | NOVARTIS AG (CH) | 2011-05-12 | — | — | WO | claimed |
| US-20110102736-A1 | SILICONE HYDROGEL LENS WITH A GRAFTED HYDROPHILIC COATING | ALCON INC. (CH) | 2011-05-05 | — | — | US | claimed |
| WO-2010135481-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | NOVARTIS AG (CH) | 2010-11-25 | — | — | WO | claimed |
| US-20100298446-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | ALCON INC. (CH) | 2010-11-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260132236-A1 | LIGHT ABSORBERS FOR OPHTHALMC LENS MATERALS AND DEVICES | RAD51, ERCC1, LANCL2 | FAAH 568/4885MGLL 1304/4885CYP19A1 2887/4885 |
| US-20260042269-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | CRYZ, STRA6, PHOSPHO1 | FAAH 1726/4885MGLL 1256/4885CYP19A1 4091/4885 |
| US-20100298446-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | ATRIP, ATR, MACF1 | FAAH 2807/4885MGLL 2940/4885CYP19A1 3725/4885 |
| US-12595368-B2 | UV/HEVL-filtering contact lenses | UACA, HSPA4L, RAD54L | FAAH 3553/4885MGLL 2234/4885CYP19A1 4150/4885 |
| US-12570784-B2 | Method for making embedded hydrogel contact lenses | CRYAB, CRYZ, CRYAA | FAAH 4264/4885MGLL 2886/4885CYP19A1 3732/4885 |
| US-20120029111-A1 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | PIGS, ELOVL1, HACD2 | FAAH 208/4885MGLL 524/4885CYP19A1 4399/4885 |
| US-20260042268-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | STRA6, CRYZ, SMCHD1 | FAAH 2950/4885MGLL 1865/4885CYP19A1 3266/4885 |
| US-12638614-B2 | Method for making silicone hydrogel contact lenses | SMCHD1, CRYAA, CRYZ | FAAH 913/4885MGLL 590/4885CYP19A1 3074/4885 |
| US-20260131506-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | CRYZ, CRYAB, CRYAA | FAAH 3508/4885MGLL 2601/4885CYP19A1 2327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.