Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6398519 | 0.84 | LMNA (0.43) | CHRM2TAAR1TLR2ALDH1A1 | |
| SCHEMBL4538523 | 0.82 | CHRM2 (0.58) | CHRM2ALDH1A1 | |
| SCHEMBL6404056 | 0.82 | CHRM2 (0.58) | CHRM2ALDH1A1 | |
| SCHEMBL11728106 | 0.72 | LIPG (0.34) | KDM4ETLR2 | |
| SCHEMBL11739851 | 0.72 | TLR2 (0.39) | TLR2 | |
| SCHEMBL21800050 | 0.71 | TAS1R3 (0.38) | KDM4EKMT2AMEN1 | |
| SCHEMBL3765090 | 0.71 | TAAR1 (0.47) | CHRM2TAAR1 | |
| SCHEMBL21799898 | 0.70 | KDM4E (0.43) | KDM4EKMT2AALDH1A1MAPK1MEN1 | |
| SCHEMBL6313952 | 0.70 | L3MBTL1 (0.54) | CHRM2TAAR1KDM4EKMT2AALDH1A1 | |
| SCHEMBL25620575 | 0.70 | NR3C1 (0.42) | TAAR1KDM4ENR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1890995-A2 | SYNTHESIS OF ORGANIC COMPOUNDS | Alma Mater Studiorum -Universita' di Bologna (IT) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006134457-A2 | 2,5-BIS-DIAMIMNE [1 , 4] BENZOQUINONE-DERIVATIVES | ALMA MATER STUDIORUM-UNIVERSITA' DI BOLOGNA (IT) | 2006-12-21 | — | — | WO | disclosed |