Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.51 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.49 |
| ▸ | DNM2 | P50570 | 4/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10338468 | 0.90 | CNR1 (0.52) | TLR8KCNH3CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18913398 | 0.87 | DNM2 (0.47) | TLR8DNM2SOAT1NPC1ALDH1A1 | |
| SCHEMBL9299788 | 0.87 | TLR8 (0.53) | TLR8KCNH3CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL11498443 | 0.87 | TLR8 (0.45) | TLR8KCNH3CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL17364403 | 0.85 | CHRNB2 (0.51) | TLR8CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11721783 | 0.82 | TLR8 (0.51) | TLR8CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8396192 | 0.81 | TLR8 (0.58) | TLR8CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL30449687 | 0.79 | CYP2C19 (0.59) | TLR8SOAT1HCAR3 | |
| SCHEMBL515358 | 0.79 | CYP2C19 (0.59) | TLR8SOAT1HCAR3 | |
| SCHEMBL1234357 | 0.78 | NCF1 (0.55) | TLR8KCNH3DNM2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070189991-A1 | Cosmetic compositon comprising a (Thio)urethane/ (thio)urea copolymer capable of forming at least 3 hydrogen bonds, and a method of cosmetic treatment | L'OREAL S.A. (FR) | 2007-08-16 | — | — | US | claimed |
| EP-1797868-A1 | Cosmetic composition comprising a (thio)urethane/(thio)urea copolymer capable of forming at least 3 hydrogen bonds, and process for cosmetic treatment | L'Oréal (FR) | 2007-06-20 | — | — | EP | claimed |
| EP-1797867-A1 | Cosmetic or pharmaceutical composition comprising a copolymer containing at least one ionisable group, and cosmetic treatment | L'Oréal (FR) | 2007-06-20 | — | — | EP | claimed |
| EP-3548544-B1 | AQUEOUS DISPERSION OF POLYALKENE SUPRAMOLECULAR POLYMER AND ITS USE IN COSMETICS | OREAL (FR) | 2021-07-21 | — | — | EP | disclosed |
| US-10973751-B2 | Hair dyeing process comprising a pigment and an aqueous dispersion of supramolecular polymer | L'OREAL (FR) | 2021-04-13 | — | — | US | disclosed |
| US-20200108007-A1 | HAIR DYEING PROCESS COMPRISING A PIGMENT AND AN AQUEOUS DISPERSION OF SUPRAMOLECULAR POLYMER | L'OREAL (FR) | 2020-04-09 | — | — | US | disclosed |
| EP-3606502-A1 | HAIR DYEING PROCESS COMPRISING A PIGMENT AND AN AQUEOUS DISPERSION OF SUPRAMOLECULAR POLYMER | L'Oreal (FR) | 2020-02-12 | — | — | EP | disclosed |
| EP-3548544-A1 | AQUEOUS DISPERSION OF POLYALKENE SUPRAMOLECULAR POLYMER AND ITS USE IN COSMETICS | L'OREAL (FR) | 2019-10-09 | — | — | EP | disclosed |
| US-20190274946-A1 | AQUEOUS DISPERSION OF POLYALKENE SUPRAMOLECULAR POLYMER AND ITS USE IN COSMETICS | L'OREAL (FR) | 2019-09-12 | — | — | US | disclosed |
| WO-2018185335-A1 | HAIR DYEING PROCESS COMPRISING A PIGMENT AND AN AQUEOUS DISPERSION OF SUPRAMOLECULAR POLYMER | L'OREAL (FR) | 2018-10-11 | — | — | WO | disclosed |
| WO-2018099827-A1 | AQUEOUS DISPERSION OF POLYALKENE SUPRAMOLECULAR POLYMER AND ITS USE IN COSMETICS | L'OREAL (FR) | 2018-06-07 | — | — | WO | disclosed |
| WO-2006034474-A2 | NOVEL PYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | REDDY US THERAPEUTICS, INC. (US) | 2006-03-30 | — | — | WO | disclosed |
| EP-0771190-B1 | LOCK AND KEY MICELLES | UNIV SOUTH FLORIDA (US) | 2006-03-08 | — | — | EP | disclosed |
| US-6566409-B1 | For use in radio-imaging, drug delivery, catalysis, affinity filtration for separating enantiomers | UNIVERSITY OF SOUTH FLORIDA | 2003-05-20 | — | — | US | disclosed |
| EP-0771190-A4 | LOCK AND KEY MICELLES | UNIV SOUTH FLORIDA (US) | 2000-12-20 | — | — | EP | disclosed |
| US-6130209-A | Lock and key micelles | UNIVERSITY OF SOUTH FLORIDA (US) | 2000-10-10 | — | — | US | disclosed |
| US-5863919-A | Lock and key micelles and monomer building blocks therefor | UNIVERSITY OF SOUTH FLORIDA (US) | 1999-01-26 | — | — | US | disclosed |
| US-5650101-A | Lock and key micelles | UNIVERSITY OF SOUTH FLORIDA (US) | 1997-07-22 | — | — | US | disclosed |
| EP-0771190-A1 | LOCK AND KEY MICELLES | UNIVERSITY OF SOUTH FLORIDA (US) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996003114-A1 | LOCK AND KEY MICELLES | UNIVERSITY OF SOUTH FLORIDA (US) | 1996-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190274946-A1 | AQUEOUS DISPERSION OF POLYALKENE SUPRAMOLECULAR POLYMER AND ITS USE IN COSMETICS | KRT18, DSG1, CUTA | TLR8 2127/4885KCNH3 66/4885CHRNB2 1971/4885 |
| US-20070189991-A1 | Cosmetic compositon comprising a (Thio)urethane/ (thio)urea copolymer capable of forming at least 3 hydrogen bonds, and a method of cosmetic treatment | KRT18, TST, CTH | TLR8 1771/4885KCNH3 2953/4885CHRNB2 3300/4885 |
| US-10973751-B2 | Hair dyeing process comprising a pigment and an aqueous dispersion of supramolecular polymer | TYR, NACA, POLR1C | TLR8 3795/4885KCNH3 1478/4885CHRNB2 2712/4885 |
| US-20200108007-A1 | HAIR DYEING PROCESS COMPRISING A PIGMENT AND AN AQUEOUS DISPERSION OF SUPRAMOLECULAR POLYMER | TYR, NACA, POLR1C | TLR8 3795/4885KCNH3 1478/4885CHRNB2 2712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.