SCHEMBL516159

SCHEMBL516159

CCC(C)S(=O)(=O)S(=O)(=O)C(C)CC

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.33
OPRM1 P35372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL778904 0.79 TP53 (0.33) TP53TSHR
SCHEMBL12681262 0.79 TP53 (0.33) TP53TSHR
SCHEMBL7515914 0.78 TP53 (0.31) TP53
SCHEMBL10944032 0.78 TP53 (0.35) TP53
SCHEMBL10946946 0.78 TP53 (0.35) TP53
SCHEMBL552731 0.76
SCHEMBL1678417 0.76
SCHEMBL12943192 0.76
SCHEMBL899054 0.76 TP53 (0.32) TP53TSHR
SCHEMBL28900 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9282741-B2 Aniline type compounds BASF SE (DE) 2016-03-15 US disclosed
US-9174967-B2 Substituted pyrazole-containing compounds and their use as pesticides BASF SE (DE) 2015-11-03 US disclosed
US-9169253-B2 Tricyclic quinoline and quinoxaline derivatives AbbVie Deutschland GmbH & Co. KG (DE) 2015-10-27 US disclosed
US-20150250175-A1 PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS BASF SE (DE) 2015-09-10 US disclosed
US-20150250173-A1 PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS BASF SE (DE) 2015-09-10 US disclosed
US-20150237858-A1 METHOD OF CONTROLLING RYANODINE-MODULATOR INSECTICIDE RESISTANT INSECTS BASF SE (DE) 2015-08-27 US disclosed
US-20150216166-A1 Aniline Type Compounds BASF SE (DE) 2015-08-06 US disclosed
US-9096583-B2 Substituted 1,2,5-oxadiazole compounds and their use as herbicides II BASF SE (DE) 2015-08-04 US disclosed
US-9044016-B2 N-thio-anthranilamide compounds and their use as pesticides BASF SE (DE) 2015-06-02 US disclosed
US-9006485-B2 Aniline type compounds BASF SE (DE) 2015-04-14 US disclosed
US-20140155264-A1 N-Thio-Anthranilamide Compounds and Their Use as Pesticides BASF SE (DE) 2014-06-05 US disclosed
US-20140155451-A1 Aniline Type Compounds BASF SE (DE) 2014-06-05 US disclosed
US-20140080813-A1 TRICYCLIC QUINOLINE AND QUINOXALINE DERIVATIVES ABBVIE DEUTSCHLAND (DE) 2014-03-20 US disclosed
US-20140080814-A1 TRICYCLIC QUINOLINE AND QUINOXALINE DERIVATIVES AbbVie Deutschland GmbH & Co. KG (DE) 2014-03-20 US disclosed
US-8653000-B2 Imine substituted 2,4-diaryl-pyrroline derivatives as pesticides BASF SE (DE) 2014-02-18 US disclosed
US-20130190378-A1 Imine substituted 2,4-diaryl-pyrroline derivatives as pesticides BASF SE (DE) 2013-07-25 US disclosed
US-20130184320-A1 Imine Compounds BASF SE (DE) 2013-07-18 US disclosed
US-20130012381-A1 Pyridazine Compounds for Controlling Invertebrate Pests BASF SE (DE) 2013-01-10 US disclosed
US-20120291159-A1 Azoline Compounds for Combating Invertebrate Pests BASF SE (DE) 2012-11-15 US disclosed
US-20120030841-A1 Isoxazoline compounds for combating invertebrate pests BASF SE (DE) 2012-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140080813-A1 TRICYCLIC QUINOLINE AND QUINOXALINE DERIVATIVES HTR2C, HTR2A, HTR5A TP53 3874/4885TSHR 478/4885OPRM1 63/4885
US-20150216166-A1 Aniline Type Compounds ADORA3, AKT1S1, PIK3C2A TP53 2006/4885TSHR 296/4885OPRM1 1168/4885
US-20150250173-A1 PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS AADAC, ARSA, SIRT7 TP53 2976/4885TSHR 2535/4885OPRM1 4821/4885
US-20140155264-A1 N-Thio-Anthranilamide Compounds and Their Use as Pesticides NAT1, ANTXR2, ATL3 TP53 4548/4885TSHR 325/4885OPRM1 425/4885
US-20130012381-A1 Pyridazine Compounds for Controlling Invertebrate Pests PNPO, PLPBP, PIR TP53 4448/4885TSHR 3089/4885OPRM1 1004/4885
US-20140080814-A1 TRICYCLIC QUINOLINE AND QUINOXALINE DERIVATIVES HTR2C, HTR2A, HTR5A TP53 3874/4885TSHR 478/4885OPRM1 63/4885
US-20120030841-A1 Isoxazoline compounds for combating invertebrate pests PRDX5, PRDX1, PRDX2 TP53 4870/4885TSHR 4240/4885OPRM1 3127/4885
US-20140155451-A1 Aniline Type Compounds ADORA3, AKT1S1, PIK3C2A TP53 2006/4885TSHR 296/4885OPRM1 1168/4885
US-20150250175-A1 PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS MCU, AGK, MLYCD TP53 4804/4885TSHR 363/4885OPRM1 975/4885
US-20120291159-A1 Azoline Compounds for Combating Invertebrate Pests CRY1, PIR, DDT TP53 4084/4885TSHR 4588/4885OPRM1 4818/4885
US-20130190378-A1 Imine substituted 2,4-diaryl-pyrroline derivatives as pesticides DDT, PIR, INMT TP53 4074/4885TSHR 4096/4885OPRM1 3346/4885
US-20130184320-A1 Imine Compounds INMT, PNMT, IPO5 TP53 4547/4885TSHR 4622/4885OPRM1 3285/4885
US-20150237858-A1 METHOD OF CONTROLLING RYANODINE-MODULATOR INSECTICIDE RESISTANT INSECTS RYR2, RYR1, CRY1 TP53 4682/4885TSHR 293/4885OPRM1 2605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.