Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.36 |
| ▸ | TUBB | P07437 | 2/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3505271 | 1.00 | LMNA (0.57) | LMNATDP1CES2CES1MEN1 | |
| SCHEMBL5165048 | 1.00 | LMNA (0.57) | LMNATDP1CES2CES1MEN1 | |
| SCHEMBL30439628 | 0.82 | LMNA (0.64) | LMNATDP1CES2CES1MEN1 | |
| SCHEMBL1171596 | 0.81 | LMNA (0.52) | LMNATDP1CES2CES1MEN1 | |
| SCHEMBL1171598 | 0.81 | LMNA (0.52) | LMNATDP1CES2CES1MEN1 | |
| SCHEMBL30439792 | 0.81 | TDP1 (0.65) | LMNATDP1CES2CES1MEN1 | |
| SCHEMBL28702570 | 0.81 | TDP1 (0.65) | LMNATDP1CES2CES1MEN1 | |
| SCHEMBL30225789 | 0.81 | TDP1 (0.65) | LMNATDP1CES2CES1MEN1 | |
| SCHEMBL8741682 | 0.81 | LMNA (0.62) | LMNATDP1CES2CES1MEN1 | |
| SCHEMBL27498332 | 0.81 | TDP1 (0.65) | LMNATDP1CES2CES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| EP-3416729-B1 | PRO-FRAGRANCE COMPOSITION | AQDOT LTD (GB) | 2023-09-20 | — | — | EP | disclosed |
| US-11758933-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3368542-B1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2022-06-22 | — | — | EP | disclosed |
| US-11357246-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2022-06-14 | — | — | US | disclosed |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | SENOMYX, INC. | 2021-07-29 | — | — | US | disclosed |
| EP-3356356-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2021-05-26 | — | — | EP | disclosed |
| US-10695277-B2 | Pro-fragrance composition | AQDOT LIMITED (GB) | 2020-06-30 | — | — | US | disclosed |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-20190177308-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. | 2019-06-13 | — | — | US | disclosed |
| US-20170143022-A1 | Compositions Incorporating an Umami Flavor Agent | SENOMYX INC (US) | 2017-05-25 | — | — | US | disclosed |
| WO-2017075257-A2 | HIGH INTENSITY SWEETENERS | SENOMYX, INC. (US) | 2017-05-04 | — | — | WO | disclosed |
| US-20170119032-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED | 2017-05-04 | — | — | US | disclosed |
| US-20170096418-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED | 2017-04-06 | — | — | US | disclosed |
| US-20170087199-A1 | COMPOSITIONS FOR DELIVERING A COOLING SENSATION | SENOMYX INC (US) | 2017-03-30 | — | — | US | disclosed |
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | SENOMYX INC (US) | 2016-12-29 | — | — | US | disclosed |
| US-8539631-B2 | Roller for providing benefits to fabric | THE PROCTER & GAMBLE COMPANY (US) | 2013-09-24 | — | — | US | disclosed |
| EP-1765139-A1 | ROLLER FOR PROVIDING BENEFITS TO FABRIC | The Procter and Gamble Company (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006010087-A1 | ROLLER FOR PROVIDING BENEFITS TO FABRIC | THE PROCTER & GAMBLE COMPANY (US) | 2006-01-26 | — | — | WO | disclosed |
| US-20060005333-A1 | Roller for providing benefits to fabric | PROCTER & GAMBLE COMPANY, THE | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | LMNA 4834/4885TDP1 2650/4885CES2 1537/4885 |
| US-20170119032-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | LMNA 4834/4885TDP1 2650/4885CES2 1537/4885 |
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | TAS2R5, TAS1R1, TAS2R1 | LMNA 4440/4885TDP1 1437/4885CES2 785/4885 |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM4, TRPM6 | LMNA 3784/4885TDP1 3125/4885CES2 2849/4885 |
| US-11357246-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | LMNA 4834/4885TDP1 2650/4885CES2 1537/4885 |
| US-20170143022-A1 | Compositions Incorporating an Umami Flavor Agent | TAS2R8, TAS2R45, TAS2R40 | LMNA 2068/4885TDP1 3893/4885CES2 2085/4885 |
| US-20190177308-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM6, TRPM4 | LMNA 4164/4885TDP1 2442/4885CES2 2352/4885 |
| US-20170087199-A1 | COMPOSITIONS FOR DELIVERING A COOLING SENSATION | TRPA1, PDE6G, PDE6D | LMNA 4541/4885TDP1 907/4885CES2 549/4885 |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | LMNA 4834/4885TDP1 2650/4885CES2 1537/4885 |
| US-11758933-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | LMNA 4834/4885TDP1 2650/4885CES2 1537/4885 |
| US-20170096418-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM6, TRPM4 | LMNA 4164/4885TDP1 2442/4885CES2 2352/4885 |
| US-10695277-B2 | Pro-fragrance composition | COPS5, COPS8, CBR3 | LMNA 2903/4885TDP1 4750/4885CES2 470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.