Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 10/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5457380 | 0.76 | MAOA (0.48) | MAOAALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL6281277 | 0.72 | LOXL2 (0.44) | MAOAALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL7958885 | 0.71 | ALDH1A1 (0.45) | MAOAALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL7236286 | 0.71 | MAOA (0.68) | MAOAALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL6285040 | 0.70 | MAOA (0.72) | MAOAALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL4039513 | 0.69 | ABCG2 (0.46) | MAOAALDH1A1KDM4ELMNAELANE | |
| SCHEMBL14443973 | 0.69 | IKBKB (0.58) | MAOAKDM4ECYP3A4 | |
| SCHEMBL14443979 | 0.69 | NUDT1 (0.53) | MAOAALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL20346660 | 0.69 | MAOA (0.62) | MAOAALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL7948739 | 0.68 | KDM4E (0.41) | MAOAALDH1A1KDM4ELMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585740-A4 | PROCESS TO PREPARE PSOROSPERMIN | CYLENE PHARMACEUTICALS INC (US) | 2007-06-13 | — | — | EP | disclosed |
| EP-1585740-A2 | PROCESS TO PREPARE PSOROSPERMIN | Cylene Pharmaceuticals, Inc. (US) | 2005-10-19 | — | — | EP | disclosed |
| US-6933396-B2 | Process to prepare psorospermin | CYLENE PHARMACEUTICALS (US) | 2005-08-23 | — | — | US | disclosed |
| US-20040102515-A1 | Process to prepare psorospermin | CYLENE PHARMACEUTICALS | 2004-05-27 | — | — | US | disclosed |
| WO-2004019888-A2 | PROCESS TO PREPARE PSOROSPERMIN | CYLENE PHARMACEUTICALS, INC. (US) | 2004-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102515-A1 | Process to prepare psorospermin | BPGM, DHPS, FDPS | MAOA 761/4885ALDH1A1 2689/4885KDM4E 3616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.