Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2042795 | 0.97 | PPID (0.47) | PPIDCSNK1DNPC1ALDH1A1L3MBTL1 | |
| SCHEMBL11525397 | 0.89 | ALDH1A1 (0.58) | NPC1ALDH1A1L3MBTL1MAPK1RAB9A | |
| SCHEMBL128759 | 0.88 | NPC1 (0.46) | CSNK1DNPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL6567531 | 0.88 | GAA (0.48) | NPC1ALDH1A1MAPK1GAARAB9A | |
| SCHEMBL6565313 | 0.88 | ALDH1A1 (0.43) | CSNK1DALDH1A1GAAMAPTTSHR | |
| SCHEMBL52219 | 0.87 | ALDH1A1 (0.52) | PPIDCSNK1DNPC1ALDH1A1L3MBTL1 | |
| SCHEMBL6567425 | 0.85 | L3MBTL1 (0.55) | NPC1ALDH1A1L3MBTL1MAPK1RAB9A | |
| SCHEMBL126148 | 0.85 | NPC1 (0.55) | CSNK1DNPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL4803036 | 0.85 | ABCB1 (0.47) | PPIDL3MBTL1SMN1; SMN2ABCB1LMNA | |
| SCHEMBL14487004 | 0.85 | ALDH1A1 (0.48) | CSNK1DNPC1ALDH1A1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108314643-A | A kind of synthetic method of nitrendipine metabolin | 梯尔希（南京）药物研发有限公司 | 2018-07-24 | — | — | CN | claimed |
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |
| EP-0577040-B1 | Process for the preparation of (3R,5S)-6-hydroxy-3,5-O-isopropylidene-3,5-dihydroxy-hexanoic acid, tert.-butyl ester | HOECHST AG (DE) | 1997-09-24 | — | — | EP | claimed |
| US-5399722-A | Process for preparing tert-butyl (3R,5S)-6-hydroxy-3,5--O--isopropylidene-3,5-dihydroxyhexanoate | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-21 | — | — | US | claimed |
| JP-6087851-A | — | — | None | — | — | JP | disclosed |
| US-12584153-B2 | Enzyme-mediated process for making Amberketal and Amberketal homologues | GIVAUDAN SA (CH) | 2026-03-24 | — | — | US | disclosed |
| US-20250230162-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2025-07-17 | — | — | US | disclosed |
| WO-2025137231-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| EP-4570313-A2 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2025-06-18 | — | — | EP | disclosed |
| US-20250066361-A1 | 5,6,7,7a-Tetrahydrocyclopenta[f]pyrido[1,2-h][1,7] naphthyridin-11(4bH)-one Compounds and Methods of use Use (as amended) | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2025-02-27 | — | — | US | disclosed |
| US-12221444-B2 | 5,6,7,7a-tetrahydrocyclopenta[f]pyrido[1,2-h][1,7]naphthyridin-11(4bH)-one compounds and methods of use | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2025-02-11 | — | — | US | disclosed |
| US-20250009742-A1 | NOVEL CAPSID ASSEMBLY INHIBITORS | META-IMMUNE, INC. (KR) | 2025-01-09 | — | — | US | disclosed |
| EP-0583171-A2 | (3R,5S)-3,5,6-trihydroxyhexanoic acid derivatives and methods for their production | Takasago International Corporation (JP) | 1994-02-16 | — | — | EP | disclosed |
| US-5286883-A | (3R,5S)-3,5,6-trihydroxyhexanoic acid derivative and production method thereof | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1994-02-15 | — | — | US | disclosed |
| WO-1991018887-A1 | DIAMINOPYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1991-12-12 | — | — | WO | disclosed |
| US-4933482-A | HYDROGENATION OF BETA-KETO ACID IN PRESENCE OF RUTHENIUM PHOSPHINE COMPLEX | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1990-06-12 | — | — | US | disclosed |
| US-4923865-A | Substituted 1-(1H-imidazol-4-yl)alkyl-benzamides as anti-ischemics and as alpha-2-adrenergic receptor agonists | U C B SOCIETE ANONYME (BE) | 1990-05-08 | — | — | US | disclosed |
| EP-0295109-A1 | Process for preparing optically active alcohol | Takasago International Corporation (JP) | 1988-12-14 | — | — | EP | disclosed |
| US-4720572-A | Process for the preparation of 4-acyloxy-3-oxo-butyric acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1988-01-19 | — | — | US | disclosed |
| US-4421922-A | Process for the production of tetronic acid | LONZA LTD. (CH) | 1983-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12221444-B2 | 5,6,7,7a-tetrahydrocyclopenta[f]pyrido[1,2-h][1,7]naphthyridin-11(4bH)-one compounds and methods of use | HAVCR2, HBS1L, HBG1 | PPID 535/4885CSNK1D 3143/4885NPC1 70/4885 |
| US-20250066361-A1 | 5,6,7,7a-Tetrahydrocyclopenta[f]pyrido[1,2-h][1,7] naphthyridin-11(4bH)-one Compounds and Methods of use Use (as amended) | HAVCR2, HMBS, HBS1L | PPID 908/4885CSNK1D 3172/4885NPC1 173/4885 |
| US-20250009742-A1 | NOVEL CAPSID ASSEMBLY INHIBITORS | ZC3HAV1, ZC3HAV1L, MAVS | PPID 1931/4885CSNK1D 3344/4885NPC1 1506/4885 |
| US-12584153-B2 | Enzyme-mediated process for making Amberketal and Amberketal homologues | ALKBH5, AMD1, ALKBH1 | PPID 1191/4885CSNK1D 1075/4885NPC1 4455/4885 |
| US-20250230162-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | CYP11B1, CYP11A1, CYP11B2 | PPID 2010/4885CSNK1D 1685/4885NPC1 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.