Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | GPR39 | O43194 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22061563 | 0.86 | KDM4E (0.48) | ALDH1A1SMN1; SMN2TLR4TLR2KDM4E | |
| SCHEMBL8559018 | 0.85 | LMNA (0.50) | ALDH1A1SMN1; SMN2TLR4TLR2MAPK1 | |
| SCHEMBL171707 | 0.82 | MEN1 (0.55) | DHODHALDH1A1MAPK1KDM4EPTGS2 | |
| SCHEMBL11143982 | 0.79 | PTGS2 (0.57) | SMN1; SMN2TLR4TLR2MAPK1KDM4E | |
| SCHEMBL22009620 | 0.79 | KDM4E (0.45) | DHODHTLR4TLR2MAPK1KDM4E | |
| SCHEMBL18181773 | 0.78 | DRD1 (0.52) | ALDH1A1SMN1; SMN2TLR4TLR2MAPK1 | |
| SCHEMBL12129555 | 0.78 | TLR4 (0.56) | ALDH1A1SMN1; SMN2TLR4TLR2KDM4E | |
| SCHEMBL29612417 | 0.78 | TLR4 (0.56) | ALDH1A1SMN1; SMN2TLR4TLR2KDM4E | |
| Methyl Alcohol SCHEMBL11157137 | 0.78 | GPR39 (0.51) | DHODHALDH1A1SMN1; SMN2TLR4TLR2 | |
| SCHEMBL147539 | 0.77 | LOXL2 (0.52) | ALDH1A1SMN1; SMN2TLR4TLR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085275-B | O-nitrophenol and its derivative synthesis method | 浙江工业大学 | 2017-04-12 | — | — | CN | disclosed |
| CN-104262159-B | A kind of synthetic method of ortho-nitrophenyl phenolic compound | 浙江工业大学 | 2016-08-10 | — | — | CN | disclosed |
| CN-105085275-A | O-nitrophenol and its derivative synthesis method | UNIV ZHEJIANG TECHNOLOGY | 2015-11-25 | — | — | CN | disclosed |
| CN-104262159-A | Synthesis method of o-nitrophenol compounds | UNIV ZHEJIANG TECHNOLOGY | 2015-01-07 | — | — | CN | disclosed |
| US-7202367-B2 | Process for arylating or vinylating or alkynating a nucleophilic compound | RHODIA CHIMIE (FR) | 2007-04-10 | — | — | US | disclosed |
| US-7202367-B2 | Process for arylating or vinylating or alkynating a nucleophilic compound | RHODIA CHIMIE (FR) | 2007-04-10 | — | — | US | disclosed |
| US-20050234239-A1 | Method of forming a carbon-carbon or carbon-heteroatom linkage | SHASUN PHARMA SOLUTIONS, INC. | 2005-10-20 | — | — | US | disclosed |
| US-20030236413-A1 | Catalysis in presence of a metallic element, an imine ligand and nitrogen compound as chelating compound, forming a chemical intermediates in the agrochemical and pharmaceutical fields | SHASUN PHARMA SOLUTIONS, INC. | 2003-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234239-A1 | Method of forming a carbon-carbon or carbon-heteroatom linkage | AOC1, AOC3, NUDT1 | DHODH 88/4885ALDH1A1 436/4885SMN1; SMN2 3694/4885 |
| US-20030236413-A1 | Catalysis in presence of a metallic element, an imine ligand and nitrogen compound as chelating compound, forming a chemical intermediates in the agrochemical and pharmaceutical fields | ALK, INMT, ACHE | DHODH 982/4885ALDH1A1 559/4885SMN1; SMN2 661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.