SCHEMBL535692

SCHEMBL535692

FC(F)(F)c1ccn(-c2ncccc2Cl)n1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MAPT P10636 3/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
KMT2A Q03164 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
TRPA1 O75762 2/20 0.38
PRMT6 Q96LA8 1/20 0.38
HSD11B1 P28845 4/20 0.37
OPRL1 P41146 1/20 0.36
TRPV1 Q8NER1 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15428453 0.85 TRPA1 (0.33) KDM4EL3MBTL1TRPA1HSD11B1OPRL1
SCHEMBL3277091 0.83 EPHX2 (0.48) KDM4EL3MBTL1MAPTMEN1ALDH1A1
SCHEMBL15428454 0.79 TRPA1 (0.34) MAPTTRPA1HSD11B1OPRL1TRPV1
SCHEMBL639253 0.78 HSD11B1 (0.35) KDM4EMAPTTRPA1HSD11B1TRPV1
SCHEMBL950644 0.78 KCNN4 (0.34) KDM4EL3MBTL1MAPTTRPA1HSD11B1
SCHEMBL22421823 0.78 MAPT (0.44) KDM4EL3MBTL1MAPTNPSR1MEN1
SCHEMBL28776680 0.76 KDM4E (0.44) KDM4EL3MBTL1MAPTMEN1ALDH1A1
SCHEMBL8149940 0.76 IDH1 (0.44) MAPTNPSR1NPC1RAB9APRMT6
SCHEMBL30361915 0.76 CAPN1 (0.46) KDM4EL3MBTL1MAPTNPSR1MEN1
SCHEMBL950522 0.76 RPS6KA5 (0.34) TRPA1HSD11B1TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240308988-A1 Method For Controlling Diamide Resistant Pests and Compounds Therefor SYNGENTA CROP PROTECTION AG (CH) 2024-09-19 US disclosed
US-20240251795-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2024-08-01 US disclosed
CN-108699075-A Spirocyclic derivatives 巴斯夫欧洲公司 2018-10-23 CN disclosed
US-9556141-B2 Process for preparing N-substituted 1H-pyrazole-5-carboxylate compounds and derivatives thereof BASF SE (DE) 2017-01-31 US disclosed
US-9445593-B1 Arthropodicidal anthranilamides E I DU PONT DE NEMOURS AND COMPANY (US) 2016-09-20 US disclosed
US-20160255835-A1 ARTHROPODICIDAL ANTHRANILAMIDES FMC CORPORATION 2016-09-08 US disclosed
US-20160137624-A1 PROCESS FOR PREPARING PYRIDYLPYRAZOLE COMPOUNDS AND DERIVATIVES THEREOF FROM PYRIDYLHYDRAZINE BASF SE (DE) 2016-05-19 US disclosed
WO-2016071243-A1 PROCESS FOR PREPARING HALOGENATED ALKENONE ETHERS AND THEIR USE IN THE SYNTHESIS OF ANTHRANILAMIDE PESTICIDES BASF SE (DE) 2016-05-12 WO disclosed
EP-3010898-A1 PROCESS FOR PREPARING PYRIDYLPYRAZOLE COMPOUNDS AND DERIVATIVES THEREOF FROM PYRIDYLHYDRAZINE BASF SE (DE) 2016-04-27 EP disclosed
US-20160096819-A1 PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLIC ACID COMPOUNDS AND DERIVATIVES THEREOF BASF SE (DE) 2016-04-07 US disclosed
EP-1416796-A1 METHOD FOR CONTROLLING PARTICULAR INSECT PESTS BY APPLYING ANTHRANILAMIDE COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-05-12 EP disclosed
EP-1416797-A1 ARTHROPODICIDAL ANTHRANILAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-05-12 EP disclosed
WO-2003106427-A2 PYRAZOLECARBOXAMIDE INSECTICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-12-24 WO disclosed
WO-2003062221-A1 DIAMIDE INVERTEBRATE PEST CONTROL AGENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-07-31 WO disclosed
WO-2003032731-A1 IMINOBENZOXAZINES, IMINOBENZTHIAZINES AND IMINOQUINAZOLINES FOR CONTROLLING INVERTEBRATE PESTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-04-24 WO disclosed
WO-2003027099-A1 ARTHROPODICIDAL ANTHRANILAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2003-04-03 WO disclosed
WO-2003024222-A1 ANTHRANILAMIDE ARTHROPODICIDE TREATMENT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2003-03-27 WO disclosed
WO-2003016300-A1 ORTHO-SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2003-02-27 WO disclosed
WO-2003015518-A1 METHOD FOR CONTROLLING PARTICULAR INSECT PESTS BY APPLYING ANTHRANILAMIDE COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-02-27 WO disclosed
WO-2003015519-A1 ARTHROPODICIDAL ANTHRANILAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240308988-A1 Method For Controlling Diamide Resistant Pests and Compounds Therefor DDT, NOS1, SLC11A2 KDM4E 2707/4885L3MBTL1 274/4885MAPT 594/4885
US-20240251795-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR DDT, NOS1, SLC11A2 KDM4E 2663/4885L3MBTL1 421/4885MAPT 343/4885
US-20160255835-A1 ARTHROPODICIDAL ANTHRANILAMIDES ANTXR2, NIT2, NAAA KDM4E 1491/4885L3MBTL1 859/4885MAPT 4869/4885
US-20160137624-A1 PROCESS FOR PREPARING PYRIDYLPYRAZOLE COMPOUNDS AND DERIVATIVES THEREOF FROM PYRIDYLHYDRAZINE CYP4F3, CYP3A5, PDXK KDM4E 2379/4885L3MBTL1 4857/4885MAPT 3054/4885
US-20160096819-A1 PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLIC ACID COMPOUNDS AND DERIVATIVES THEREOF CA3, CA2, CA1 KDM4E 2006/4885L3MBTL1 3553/4885MAPT 3474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.