Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14626184 | 0.81 | SLC5A2 (0.35) | ALDH1A1CYP3A4MAPK1PDE4D | |
| SCHEMBL14415238 | 0.81 | SLC5A2 (0.35) | ALDH1A1CYP3A4MAPK1PDE4D | |
| SCHEMBL5361040 | 0.78 | PIN1 (0.37) | ALDH1A1PDE4D | |
| SCHEMBL14408048 | 0.78 | PIN1 (0.37) | ALDH1A1PDE4D | |
| SCHEMBL15161369 | 0.72 | ALDH1A1 (0.53) | ALDH1A1CYP3A4MAPK1ABCB1PTAFR | |
| SCHEMBL15161417 | 0.72 | ALDH1A1 (0.53) | ALDH1A1CYP3A4MAPK1ABCB1PTAFR | |
| SCHEMBL1973506 | 0.70 | XDH (0.47) | ALDH1A1CYP3A4MAPK1ABCB1XDH | |
| Catechin Tetramethylether SCHEMBL30991591 | 0.70 | CYP3A4 (0.81) | ALDH1A1CYP3A4MAPK1ABCB1 | |
| Catechin Tetramethylether SCHEMBL28731348 | 0.70 | CYP3A4 (0.81) | ALDH1A1CYP3A4MAPK1ABCB1 | |
| Catechin Tetramethylether SCHEMBL1430853 | 0.70 | CYP3A4 (0.81) | ALDH1A1CYP3A4MAPK1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268240-B2 | Synthetic methods for polyphenols | MARS, INC. | 2007-09-11 | — | — | US | disclosed |
| US-6849746-B2 | Synthetic methods for polyphenols | MARS, INC. (US) | 2005-02-01 | — | — | US | disclosed |
| US-20040236123-A1 | Synthetic methods for polyphenols | M&M/MARS INC. | 2004-11-25 | — | — | US | disclosed |
| US-20040235941-A1 | Dimer digallate compositions | MARS, INCORPORATED | 2004-11-25 | — | — | US | disclosed |
| US-20030176620-A1 | Synthetic methods for polyphenols | MARS INCORPORATED | 2003-09-18 | — | — | US | disclosed |
| US-6528664-B2 | Synthetic methods for polyphenols | MARS, INCORPORATED | 2003-03-04 | — | — | US | disclosed |
| EP-1027345-B1 | SYNTHETIC METHODS FOR POLYPHENOLS | MARS INC (US) | 2003-02-19 | — | — | EP | disclosed |
| US-20020128493-A1 | Coupling flavonoid-like compounds having protected hydroxy groups by functionalizing the C-4; oxidative dehydrogenation to form dimers and oligomers; efficiency; anticarciogenic agents; breast cancer | MARS, INCORPORATED | 2002-09-12 | — | — | US | disclosed |
| US-6420572-B1 | FLAVANOID DERIVATIVES AND PHENOLIC DERIVATIVES WITH HALOGENATION | MARS, INCORPORATED | 2002-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236123-A1 | Synthetic methods for polyphenols | MLN, NQO1, NOD2 | ALDH1A1 1751/4885CYP3A4 178/4885MAPK1 3009/4885 |
| US-20020128493-A1 | Coupling flavonoid-like compounds having protected hydroxy groups by functionalizing the C-4; oxidative dehydrogenation to form dimers and oligomers; efficiency; anticarciogenic agents; breast cancer | GPX4, NOX4, TPD52L2 | ALDH1A1 745/4885CYP3A4 18/4885MAPK1 2556/4885 |
| US-20040235941-A1 | Dimer digallate compositions | NOD2, GID4, GPX4 | ALDH1A1 1937/4885CYP3A4 304/4885MAPK1 2879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.