Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL28078379 | 1.00 | GPR84 (0.50) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL8101208 | 0.83 | PRKCA (0.50) | KMT2AMEN1PRKCAMAPT | |
| SCHEMBL10535223 | 0.83 | MAPT (0.60) | ALDH1A1KMT2AMEN1PRKCAMAPT | |
| SCHEMBL8101213 | 0.83 | MAPT (0.60) | ALDH1A1KMT2AMEN1PRKCAMAPT | |
| Stearic Acid SCHEMBL3334740 | 0.81 | GPR84 (0.61) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL23781813 | 0.81 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| Behenic Acid SCHEMBL1857976 | 0.81 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL5739296 | 0.81 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL9107897 | 0.81 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL10596204 | 0.81 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108623459-A | A kind of preparation method of diacetyl glycerin monostearate | 长沙市如虹医药科技股份有限公司 | 2018-10-09 | — | — | CN | claimed |
| JP-10195306-A | — | — | None | — | — | JP | disclosed |
| CN-115843884-B | Oat milk and preparation method thereof | 内蒙古蒙牛乳业（集团）股份有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-115843884-A | Oat milk and preparation method thereof | 内蒙古蒙牛乳业（集团）股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
| US-20220040074-A1 | Decolorization of Dyed Keratinic Fibers | HENKEL AG & CO. KGAA (DE) | 2022-02-10 | — | — | US | disclosed |
| US-10925369-B2 | Permanent waving method with improved nourishing and wave effect | HENKEL AG & CO. KGAA (DE) | 2021-02-23 | — | — | US | disclosed |
| US-10653598-B2 | Decoloring of dyed keratin fibers | HENKEL AG & CO. KGAA (DE) | 2020-05-19 | — | — | US | disclosed |
| WO-2019109243-A1 | Cosmetic composition for permanently changing the shape of keratinous fibers | HENKEL AG & CO.KGAA (DE) | 2019-06-13 | — | — | WO | disclosed |
| CN-108623459-A | A kind of preparation method of diacetyl glycerin monostearate | 长沙市如虹医药科技股份有限公司 | 2018-10-09 | — | — | CN | disclosed |
| CN-108623459-A | A kind of preparation method of diacetyl glycerin monostearate | 长沙市如虹医药科技股份有限公司 | 2018-10-09 | — | — | CN | disclosed |
| US-6790240-B2 | SHAPED BODY CONTAINS AT LEAST ONE DYE PRECURSOR, AT LEAST ONE OXIDIZING AGENT, AND AT LEAST ONE ALKALINIZING AGENT. | HENKEL KOMMANDITGESELLSCHAFT AUG AKTIEN (DE) | 2004-09-14 | — | — | US | disclosed |
| EP-1029890-B1 | Aliphatic polyester composition and stretched film obtained from said composition | MITSUI CHEMICALS INC (JP) | 2004-07-28 | — | — | EP | disclosed |
| US-20040064901-A1 | Enzymatic coloring agents | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2004-04-08 | — | — | US | disclosed |
| US-6673123-B2 | FOR USE IN HAIR-COLORING PREPARATIONS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2004-01-06 | — | — | US | disclosed |
| US-20030172469-A1 | Shaped body contains at least one dye precursor, at least one oxidizing agent, and at least one alkalinizing agent. | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2003-09-18 | — | — | US | disclosed |
| US-20030033678-A1 | Shaped bodies for forming cosmetic preparations | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2003-02-20 | — | — | US | disclosed |
| US-20030028978-A1 | Solid colorant for keratin fibers | HENKEL AG & CO. KGAA (DE) | 2003-02-13 | — | — | US | disclosed |
| US-20020194684-A1 | Solid colorant for keratin fibers | HENKEL AG & CO. KGAA (DE) | 2002-12-26 | — | — | US | disclosed |
| US-20020059682-A1 | Enzymatic dyeing agent | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2002-05-23 | — | — | US | disclosed |
| JP-H10195306-A | BIODEGRADABLE PLASTIC COMPOSITION AND ITS PRODUCTION | AGENCY OF IND SCIENCE & TECHNOL | 1998-07-28 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10653598-B2 | Decoloring of dyed keratin fibers | KRT18, CUTA, ALDH1A1 | GPR84 4065/4885PPARG 2988/4885PPARD 3430/4885 |
| US-20020059682-A1 | Enzymatic dyeing agent | KRT18, TYR, PPOX | GPR84 3368/4885PPARG 3312/4885PPARD 3617/4885 |
| US-20030172469-A1 | Shaped body contains at least one dye precursor, at least one oxidizing agent, and at least one alkalinizing agent. | KRT18, PLOD1, CKMT1A; CKMT1B | GPR84 1809/4885PPARG 2833/4885PPARD 2605/4885 |
| US-20040064901-A1 | Enzymatic coloring agents | GLA, HEXA, HSD17B14 | GPR84 2126/4885PPARG 1523/4885PPARD 1220/4885 |
| US-20030033678-A1 | Shaped bodies for forming cosmetic preparations | PLIN5, DSG1, FABP4 | GPR84 3437/4885PPARG 110/4885PPARD 254/4885 |
| US-20020194684-A1 | Solid colorant for keratin fibers | KRT18, IK, CKAP4 | GPR84 2074/4885PPARG 2115/4885PPARD 1500/4885 |
| US-20220040074-A1 | Decolorization of Dyed Keratinic Fibers | KRT18, CUTA, DSG1 | GPR84 4154/4885PPARG 2478/4885PPARD 2738/4885 |
| US-10925369-B2 | Permanent waving method with improved nourishing and wave effect | KRT18, CUTA, PCNA | GPR84 2030/4885PPARG 2043/4885PPARD 3433/4885 |
| US-20030028978-A1 | Solid colorant for keratin fibers | KRT18, IK, VIM | GPR84 1949/4885PPARG 3473/4885PPARD 1816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.