SCHEMBL5371000

SCHEMBL5371000

O=P(O)(O)OC(Cl)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.52
PTPN1 P18031 4/20 0.44
TSHR P16473 2/20 0.44
PTPRC P08575 1/20 0.41
PDPK1 O15530 1/20 0.41
MTOR P42345 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
HIF1A Q16665 1/20 0.40
SRC P12931 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
GGPS1 O95749 2/20 0.38
LAP3 P28838 3/20 0.38
ANPEP P15144 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23827953 0.85 FDPS (0.46) FDPSPTPN1TSHRPTPRCSMN1; SMN2
SCHEMBL11120024 0.81 FDPS (0.55) FDPSPTPN1TSHRPTPRCPDPK1
SCHEMBL11535809 0.76 FDPS (0.50) FDPSPTPN1TSHRPTPRCPDPK1
SCHEMBL21121849 0.75 FDPS (0.49) FDPSPTPN1TSHRPDPK1MTOR
SCHEMBL29182980 0.75 FDPS (0.62) FDPSPTPN1TSHRPTPRCSMN1; SMN2
SCHEMBL27514707 0.74 FDPS (0.51) FDPSPTPN1TSHRPTPRCPDPK1
SCHEMBL3728040 0.74 FDPS (0.47) FDPSPTPN1TSHRPTPRCPDPK1
SCHEMBL11318157 0.74 FDPS (0.47) FDPSPTPN1TSHRPTPRCPDPK1
SCHEMBL29127601 0.71 PTPN1 (0.47) FDPSPTPN1TSHRSRCCYP1A2
SCHEMBL29049152 0.71 PTPN1 (0.47) FDPSPTPN1TSHRSRCCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122055373-A Bridged tricyclic carbamoyl pyridone compounds and uses thereof 吉利德科学公司 2026-05-15 CN disclosed
US-20260035394-A1 1`-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF GILEAD SCIENCES INC (US) 2026-02-05 US disclosed
EP-4644394-A2 ANTIVIRAL COMPOUNDS Gilead Sciences, Inc. (US) 2025-11-05 EP disclosed
EP-4106876-B1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES INC (US) 2025-09-17 EP disclosed
US-12404289-B2 1′-cyano nucleoside analogs and uses thereof GILEAD SCIENCES, INC. (US) 2025-09-02 US disclosed
WO-2025101944-A1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT DEGRADE SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A Plexium, Inc. (US) 2025-05-15 WO disclosed
US-20250002513-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2025-01-02 US disclosed
US-20240336583-A1 BENZO-RING-CONTAINING DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF SHUJING BIOPHARMA CO., LTD (CN) 2024-10-10 US disclosed
US-20240287109-A1 1'-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF GILEAD SCIENCES, INC. 2024-08-29 US disclosed
US-12030903-B2 Antiviral compounds GILEAD SCIENCES, INC. (US) 2024-07-09 US disclosed
US-7244718-B2 Water soluble prodrugs of hindered alcohols UNIVERSITY OF KANSAS (US) 2007-07-17 US disclosed
EP-1683803-A1 Water soluble prodrugs of hindered alcohols or phenols THE UNIVERSITY OF KANSAS (US) 2006-07-26 EP disclosed
EP-1102776-B1 WATER SOLUBLE PRODRUGS OF HINDERED PHENOLS UNIV KANSAS (US) 2006-03-08 EP disclosed
US-20050090431-A1 Water soluble prodrugs of hindered alcohols UNIVERSITY OF KANSAS (US) 2005-04-28 US disclosed
US-6872838-B2 Water soluble prodrugs of hindered alcohols UNIVERSITY OF KANSAS (US) 2005-03-29 US disclosed
US-20030176324-A1 Water soluble prodrugs of hindered alcohols UNIVERSITY OF KANSAS 2003-09-18 US disclosed
US-6451776-B2 A WATER SOLUBLE PHOPHONOOXYMETHYL ETHERS OF HINDERED ALCOHOL AND PHENOL CONTAINING PHARMECEUTICALS, SUCH AS CAMPTOTHECIN, PROPOFOL, ETOPOSIDE, VITAMIN E, AND CYCLOSPROIN A UNIVERSITY OF KANSAS 2002-09-17 US disclosed
US-20010025035-A1 Water soluble prodrugs of hindered alcohols UNIVERSITY OF KANSAS 2001-09-27 US disclosed
EP-1102776-A1 WATER SOLUBLE PRODRUGS OF HINDERED ALCOHOLS OR PHENOLS THE UNIVERSITY OF KANSAS (US) 2001-05-30 EP disclosed
WO-2000008033-A1 WATER SOLUBLE PRODRUGS OF HINDERED ALCOHOLS OR PHENOLS THE UNIVERSITY OF KANSAS (US) 2000-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030176324-A1 Water soluble prodrugs of hindered alcohols ADH1A, ADH5, ADH1C FDPS 1115/4885PTPN1 2400/4885TSHR 1482/4885
US-12030903-B2 Antiviral compounds EIF2AK2, MAVS, DUT FDPS 427/4885PTPN1 3204/4885TSHR 4684/4885
US-20050090431-A1 Water soluble prodrugs of hindered alcohols ADH1A, ADH5, ADH1C FDPS 1115/4885PTPN1 2400/4885TSHR 1482/4885
US-20240336583-A1 BENZO-RING-CONTAINING DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF GABRA1, GABRA4, GABRA5 FDPS 555/4885PTPN1 4569/4885TSHR 2212/4885
US-20240287109-A1 1'-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF TYMP, PNP, DUT FDPS 540/4885PTPN1 2930/4885TSHR 4786/4885
US-20250002513-A1 ANTIVIRAL COMPOUNDS EIF2AK2, MAVS, DUT FDPS 427/4885PTPN1 3204/4885TSHR 4684/4885
US-12404289-B2 1′-cyano nucleoside analogs and uses thereof TYMP, PNP, DUT FDPS 597/4885PTPN1 2956/4885TSHR 4765/4885
US-20010025035-A1 Water soluble prodrugs of hindered alcohols ADH1A, ADH5, ADH1C FDPS 1115/4885PTPN1 2400/4885TSHR 1482/4885
US-20260035394-A1 1`-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF PNP, SLC28A1, SLC29A1 FDPS 2155/4885PTPN1 545/4885TSHR 4134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.