SCHEMBL540990

SCHEMBL540990

COC(=O)[C@@H]1CCC(=O)N1C(=O)OC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.41
CHRM2 P08172 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRM3 P20309 1/20 0.40
WNT3 P56703 1/20 0.39
SFRP1 Q8N474 1/20 0.39
PTPN1 P18031 2/20 0.38
BRD4 O60885 1/20 0.37
MMP2 P08253 1/20 0.37
ANPEP P15144 1/20 0.37
MEN1 O00255 1/20 0.36
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36
ALDH1A1 P00352 1/20 0.36
ELANE P08246 1/20 0.35
PDE4B Q07343 1/20 0.35
ACE P12821 2/20 0.35
EPHX1 P07099 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL476304 1.00 KMT2A (0.41) KMT2ACHRM2CHRM1CHRM3WNT3
SCHEMBL476303 1.00 KMT2A (0.41) KMT2ACHRM2CHRM1CHRM3WNT3
SCHEMBL1604617 0.91 MMP2 (0.38) KMT2ACHRM2CHRM1CHRM3WNT3
SCHEMBL1604618 0.91 MMP2 (0.38) KMT2ACHRM2CHRM1CHRM3WNT3
SCHEMBL18018362 0.91 MMP2 (0.38) KMT2ACHRM2CHRM1CHRM3WNT3
SCHEMBL713924 0.91 CHRM2 (0.41) CHRM2CHRM1CHRM3WNT3SFRP1
SCHEMBL1372911 0.91 CHRM2 (0.41) CHRM2CHRM1CHRM3WNT3SFRP1
SCHEMBL12105456 0.91 CHRM2 (0.41) CHRM2CHRM1CHRM3WNT3SFRP1
SCHEMBL30289778 0.91 CHRM2 (0.41) CHRM2CHRM1CHRM3WNT3SFRP1
SCHEMBL6743320 0.88 CHRM2 (0.38) CHRM2CHRM1CHRM3WNT3SFRP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 503 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079866-A Preparation method of Nenoxacin side chain isomer impurity 2026-05-26 CN claimed
CN-105294700-B A kind of preparation method of 2- oxo -3,8- diazabicylo [3.2.1] octane -8- carboxylic acid tert-butyl ester 上海合全药业股份有限公司 2019-01-08 CN claimed
CN-106336371-A Synthetic method of Boc-L-Pyroglutamic acid methyl ester 成都百事兴科技实业有限公司 2017-01-18 CN claimed
EP-1229041-A1 A process for the preparation of 3-Glutamido bile ester derivatives using N-tBoc methyl pyroglutamate Bracco Imaging S.p.A. (IT) 2002-08-07 EP claimed
EP-4107166-B1 HETEROARYL COMPOUNDS FOR TREATMENT OF COMPLEMENT FACTOR D MEDIATED DISORDERS ACHILLION PHARMACEUTICALS INC (US) 2026-05-27 EP disclosed
CN-122079866-A Preparation method of Nenoxacin side chain isomer impurity 2026-05-26 CN disclosed
CN-122079866-A Preparation method of Nenoxacin side chain isomer impurity 2026-05-26 CN disclosed
US-20260116857-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOFS PARDES BIOSCIENCES INC (US) 2026-04-30 US disclosed
US-20260109669-A1 SYNTHESIS OF (2S,5R)-5-(2-CHLOROPHENYL)-1-(2'-METHOXY-[1,1'-BIPHENYL]-4- CARBONYL)PYRROLIDINE-2-CARBOXYLIC ACID EPICS THERAPEUTICS (BE) 2026-04-23 US disclosed
US-12545677-B2 Compounds useful as factor XIa inhibitors JANSSEN PHARMACEUTICA NV (BE) 2026-02-10 US disclosed
US-20260035393-A1 INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) SYROS PHARMACEUTICALS INC (US) 2026-02-05 US disclosed
US-12528769-B2 Synthesis of (2S,5R)-5-(2-chlorophenyl)-1-(2′-methoxy-[1,1′-biphenyl]-4-carbonyl)pyrrolidine-2-carboxylic acid EPICS THERAPEUTICS (BE) 2026-01-20 US disclosed
EP-1529776-A2 Amino acid derivatives and sweetening agent Ajinomoto Co., Inc. (JP) 2005-05-11 EP disclosed
EP-1523483-A2 AMINO-BICYCLIC PYRAZINONES AND PYRIDINONES AS COAGULATION SERINE PROTEASE INHIBITORS Bristol-Myers Squibb Company (US) 2005-04-20 EP disclosed
US-20050038030-A1 Amino-bicyclic pyrazinones and pyridinones as coagulation serine protease inhibitors BRISTOL-MYERS SQUIBB COMPANY 2005-02-17 US disclosed
US-20040138185-A1 Process for the preparation of 3-glutamido bile ester derivatives using n-prtotected methyl proglutamate BROCCHETTA MARINO 2004-07-15 US disclosed
WO-2004002405-A2 AMINO-BICYCLIC PYRAZINONES AND PYRIDINONES BRISTOL-MYERS SQUIBB COMPANY (US) 2004-01-08 WO disclosed
EP-1358201-A1 A PROCESS FOR THE PREPARATION OF 3-GLUTAMIDO BILE ESTER DERIVATIVES USING N-PROTECTED METHYL PYROGLUTAMATE BRACCO IMAGING S.p.A. (IT) 2003-11-05 EP disclosed
WO-2002068449-A1 A PROCESS FOR THE PREPARATION OF 3-GLUTAMIDO BILE ESTER DERIVATIVES USING N-PRTOTECTED METHYL PROGLUTAMATE BRACCO IMAGING S.P.A. (IT) 2002-09-06 WO disclosed
EP-1229041-A1 A process for the preparation of 3-Glutamido bile ester derivatives using N-tBoc methyl pyroglutamate Bracco Imaging S.p.A. (IT) 2002-08-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260116857-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOFS CTRC, CTRL, CTSL KMT2A 4265/4885CHRM2 4756/4885CHRM1 4566/4885
US-20040138185-A1 Process for the preparation of 3-glutamido bile ester derivatives using n-prtotected methyl proglutamate GCG, GPBAR1, OTC KMT2A 3026/4885CHRM2 2685/4885CHRM1 1181/4885
US-20260109669-A1 SYNTHESIS OF (2S,5R)-5-(2-CHLOROPHENYL)-1-(2'-METHOXY-[1,1'-BIPHENYL]-4- CARBONYL)PYRROLIDINE-2-CARBOXYLIC ACID TPMT, CLIC1, CYP2S1 KMT2A 1675/4885CHRM2 1068/4885CHRM1 871/4885
US-12545677-B2 Compounds useful as factor XIa inhibitors F2, F11, F10 KMT2A 3070/4885CHRM2 4441/4885CHRM1 3928/4885
US-20050038030-A1 Amino-bicyclic pyrazinones and pyridinones as coagulation serine protease inhibitors TFPI, F5, F2 KMT2A 2629/4885CHRM2 4543/4885CHRM1 4094/4885
US-20260035393-A1 INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) CDK7, CDK3, CCNI KMT2A 1303/4885CHRM2 4473/4885CHRM1 4128/4885
US-12528769-B2 Synthesis of (2S,5R)-5-(2-chlorophenyl)-1-(2′-methoxy-[1,1′-biphenyl]-4-carbonyl)pyrrolidine-2-carboxylic acid ADH1C, ADH1A, IL6 KMT2A 1575/4885CHRM2 498/4885CHRM1 402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.