Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL544866 | 0.83 | PKM (0.38) | PKMCPB2ALDH1A1 | |
| SCHEMBL545682 | 0.77 | KMT2A (0.34) | — | |
| SCHEMBL10073917 | 0.75 | SPHK1 (0.36) | CPB2ALDH1A1 | |
| SCHEMBL10073879 | 0.71 | CTSK (0.34) | CPB2ALDH1A1 | |
| SCHEMBL10073918 | 0.70 | SPHK1 (0.39) | CPB2ALDH1A1 | |
| SCHEMBL544862 | 0.68 | LMNA (0.36) | PKMCPB2ALDH1A1 | |
| SCHEMBL27809137 | 0.67 | ALDH1A1 (0.35) | CPB2ALDH1A1 | |
| SCHEMBL544947 | 0.67 | LMNA (0.36) | ALDH1A1 | |
| SCHEMBL545374 | 0.67 | RORC (0.42) | ALDH1A1 | |
| SCHEMBL10071243 | 0.65 | PKM (0.46) | PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110699-B2 | Cobalt-catalyzed asymmetric cyclopropanation of alkenes with α-nitrodiazoacetates | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-02-07 | — | — | US | disclosed |
| US-20100081838-A1 | Cobalt-Catalyzed Asymmetric Cyclopropanation of Alkenes with alpha-Nitrodiazoacetates | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081838-A1 | Cobalt-Catalyzed Asymmetric Cyclopropanation of Alkenes with alpha-Nitrodiazoacetates | PPOX, IDH3A, HMOX2 | PKM 2758/4885CPB2 2365/4885ALDH1A1 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.