SCHEMBL550366

SCHEMBL550366

CC(C)NC(=O)c1c(I)cccc1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
PKM P14618 2/20 0.40
KMT2A Q03164 5/20 0.40
MEN1 O00255 4/20 0.40
TDP1 Q9NUW8 1/20 0.40
KDM4E B2RXH2 4/20 0.40
HPGD P15428 2/20 0.40
HTT P42858 2/20 0.40
XDH P47989 3/20 0.39
HSD17B10 Q99714 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
TAS1R2 Q8TE23 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NLRP3 Q96P20 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL550367 0.87 ALDH1A1 (0.43) ALDH1A1PKMKMT2AMEN1TDP1
SCHEMBL552115 0.83 MEN1 (0.41) ALDH1A1PKMKMT2AMEN1TDP1
SCHEMBL29459710 0.83 MEN1 (0.35) ALDH1A1PKMKMT2AMEN1TDP1
SCHEMBL551877 0.83 MEN1 (0.41) ALDH1A1PKMKMT2AMEN1TDP1
SCHEMBL4974939 0.82 MEN1 (0.40) ALDH1A1PKMKMT2AMEN1TDP1
SCHEMBL4978507 0.82 MEN1 (0.40) ALDH1A1PKMKMT2AMEN1TDP1
SCHEMBL551896 0.81 ALDH1A1 (0.47) ALDH1A1KMT2AMEN1TDP1KDM4E
SCHEMBL551858 0.81 ALB (0.47) ALDH1A1KMT2AMEN1HTTNPSR1
SCHEMBL551795 0.81 PBRM1 (0.49) ALDH1A1KMT2AMEN1HPGDTAS1R3
SCHEMBL6295545 0.80 MEN1 (0.40) ALDH1A1KMT2AMEN1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6362369-B1 None US disclosed
US-8110689-B2 Benzanilides with insecticidal activity BAYER CROPSCIENE AG (DE) 2012-02-07 US disclosed
US-20100130743-A1 HETEROCYCLE-SUBSTITUTED, N-PHENYL-PHTHALAMIDE DERIVATIVES, RELATED COMPOUNDS AND THEIR USE AS INSECTICIDES BAYER CROPSCIENCE AG (DE) 2010-05-27 US disclosed
US-20100062937-A1 BENZANILIDES WITH INSECTICIDAL ACTIVITY BAYER CROPSCIENCE AG (DE) 2010-03-11 US disclosed
US-7674807-B2 Heterocycle-substituted n-phenyl-phthalamide derivatives, related compounds and their use as insecticides BAYER CROPSCIENCE AG (DE) 2010-03-09 US disclosed
EP-1727804-B1 N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES BAYER CROPSCIENCE AG (DE) 2009-11-04 EP disclosed
EP-1700844-B1 Phthalic acid diamide derivatives, agricultural and horticultural insecticides and a method for application of the insecticides NIHON NOHYAKU CO LTD (JP) 2009-01-14 EP disclosed
EP-1893567-A1 BENZANILIDES WITH INSECTICIDAL ACTIVITY Bayer CropScience AG (DE) 2008-03-05 EP disclosed
US-20070299085-A1 N1-((Pyrazol-1-Ymethyl)-2-Methylphenyl)-Phatalamide Derivatives And Related Compounds Insecticides BAYER CROPSCIENCE AG (DE) 2007-12-27 US disclosed
US-20070043011-A1 Substituted benzanilide compound and noxious organism controlling agent MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-02-22 US disclosed
US-20050250822-A1 Substituted benzanilide compound and noxious organism controlling agent NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-11-10 US disclosed
WO-2005095351-A1 N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES BAYER CROPSCIENCE AG (DE) 2005-10-13 WO disclosed
EP-1538138-A1 SUBSTITUTED BENZANILIDE COMPOUND AND PEST CONTROL AGENT NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 2005-06-08 EP disclosed
WO-2004080984-A1 INSECTICIDAL PHTHALAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2004-09-23 WO disclosed
EP-1447396-A1 Phthalic acid diamide derivatives, agriculture and horticultural insecticides, and a method for application of the insecticides NIHON NOHYAKU CO., LTD. (JP) 2004-08-18 EP disclosed
US-6559341-B2 Phthalic acid diamide derivatives, fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides NIHON NOHYAKU CO., LTD. (JP) 2003-05-06 US disclosed
US-20030055287-A1 Phthalic acid diamide derivatives, fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides AIR MOTION TECHNOLOGIES, LLC 2003-03-20 US disclosed
US-6362369-B2 CONTROLLING INSECTS IN CROPS NIHON NOHYAKU CO., LTD. (JP) 2002-03-26 US disclosed
US-20010041814-A1 PHTHALIC ACID DIAMIDE DERIVATIVES FLUORINE-CONTAINING ANILINE COMPOUNDS AS STARTING MATERIAL, AGRICULTURAL AND HORTICULTURAL INSECTICIDES, AND A METHOD FOR APPLICATION OF THE INSECTICIDES NIHON NOHYAKU CO., LTD. (JP) 2001-11-15 US disclosed
EP-0919542-A2 Phthalic acid diamide derivatives, agricultural and horticultural insecticides, and a method for application of the insecticides NIHON NOHYAKU CO., LTD. (JP) 1999-06-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100062937-A1 BENZANILIDES WITH INSECTICIDAL ACTIVITY CBR3, HCN3, HAX1 ALDH1A1 2102/4885PKM 2908/4885KMT2A 1629/4885
US-20010041814-A1 PHTHALIC ACID DIAMIDE DERIVATIVES FLUORINE-CONTAINING ANILINE COMPOUNDS AS STARTING MATERIAL, AGRICULTURAL AND HORTICULTURAL INSECTICIDES, AND A METHOD FOR APPLICATION OF THE INSECTICIDES DDT, AFF1, BCL2L2 ALDH1A1 252/4885PKM 2606/4885KMT2A 311/4885
US-20100130743-A1 HETEROCYCLE-SUBSTITUTED, N-PHENYL-PHTHALAMIDE DERIVATIVES, RELATED COMPOUNDS AND THEIR USE AS INSECTICIDES DDT, SQOR, CYP2S1 ALDH1A1 1137/4885PKM 968/4885KMT2A 765/4885
US-20030055287-A1 Phthalic acid diamide derivatives, fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides DDT, BCL2A1, BCL2L2 ALDH1A1 269/4885PKM 2510/4885KMT2A 304/4885
US-20070299085-A1 N1-((Pyrazol-1-Ymethyl)-2-Methylphenyl)-Phatalamide Derivatives And Related Compounds Insecticides CHRM1, KCNH1, DDT ALDH1A1 2697/4885PKM 1166/4885KMT2A 302/4885
US-20070043011-A1 Substituted benzanilide compound and noxious organism controlling agent L3MBTL1, L3MBTL3, L3MBTL4 ALDH1A1 888/4885PKM 3543/4885KMT2A 2055/4885
US-20050250822-A1 Substituted benzanilide compound and noxious organism controlling agent GCN1, L3MBTL3, L3MBTL4 ALDH1A1 1987/4885PKM 2782/4885KMT2A 2360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.