Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | TACR1 | P25103 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3008035 | 1.00 | CYP1A2 (0.58) | CYP1A2CYP2D6CYP2C19KDM4ENPC1 | |
| SCHEMBL3008034 | 1.00 | CYP1A2 (0.58) | CYP1A2CYP2D6CYP2C19KDM4ENPC1 | |
| SCHEMBL20128490 | 0.92 | CYP1A2 (0.51) | CYP1A2CYP2D6CYP2C19KDM4ENPC1 | |
| SCHEMBL15281063 | 0.92 | CYP1A2 (0.51) | CYP1A2CYP2D6CYP2C19KDM4ENPC1 | |
| SCHEMBL15281197 | 0.92 | CYP1A2 (0.51) | CYP1A2CYP2D6CYP2C19KDM4ENPC1 | |
| SCHEMBL10326924 | 0.91 | CYP1A2 (0.50) | CYP1A2CYP2D6CYP2C19KDM4ENPC1 | |
| SCHEMBL10326851 | 0.91 | CYP1A2 (0.50) | CYP1A2CYP2D6CYP2C19KDM4ENPC1 | |
| SCHEMBL10327087 | 0.91 | CYP1A2 (0.50) | CYP1A2CYP2D6CYP2C19KDM4ENPC1 | |
| SCHEMBL20944816 | 0.89 | CYP1A2 (0.51) | CYP1A2CYP2D6CYP2C19KDM4ENPC1 | |
| SCHEMBL15517626 | 0.89 | CYP1A2 (0.51) | CYP1A2CYP2D6CYP2C19KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348524-A1 | TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-02 | — | — | US | disclosed |
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
| CN-116535365-A | Macrocyclic diamine derivatives and their combination with adenosine receptor antagonists as ENT inhibitors for the treatment of cancer | ITEOS比利时公司 | 2023-08-04 | — | — | CN | disclosed |
| WO-2020191252-A1 | TECHNOLOGIES USEFUL FOR OLIGONUCLEOTIDE PREPARATION | WAVE LIFE SCIENCES LTD. (SG) | 2020-09-24 | — | — | WO | disclosed |
| US-20200231620-A1 | TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION | WAVE LIFE SCIENCES LTD. (SG) | 2020-07-23 | — | — | US | disclosed |
| WO-2019055951-A1 | TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION | WAVE LIFE SCIENCES LTD. (SG) | 2019-03-21 | — | — | WO | disclosed |
| US-10040760-B2 | Pyrrolidine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-08-07 | — | — | US | disclosed |
| US-20180127364-A1 | PYRROLIDINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-05-10 | — | — | US | disclosed |
| EP-2631227-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 4-CHLORO-3-HYDROXYBUTANAL COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2015-03-25 | — | — | EP | disclosed |
| US-8742176-B2 | Process for producing optically active 4-chloro-3-hydroxybutanal compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-06-03 | — | — | US | disclosed |
| US-8729294-B2 | Process for producing optically active 3-substituted-3-formyl-2-hydroxypropanoic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-05-20 | — | — | US | disclosed |
| EP-2631227-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 4-CHLORO-3-HYDROXYBUTANAL COMPOUND | Tokyo University Of Science Educational Foundation Administrative Organization (JP) | 2013-08-28 | — | — | EP | disclosed |
| US-20130217901-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 4-CHLORO-3-HYDROXYBUTANAL COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-08-22 | — | — | US | disclosed |
| US-20130137880-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-SUBSTITUTED-3-FORMYL-2-HYDROXYPROPANOIC ACID COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-30 | — | — | US | disclosed |
| EP-2578566-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-SUBSTITUTED-3-FORMYL-2-HYDROXYPROPANOIC ACID COMPOUND | Sumitomo Chemical Company Limited (JP) | 2013-04-10 | — | — | EP | disclosed |
| US-20070276142-A1 | Catalytic Asymmetric Synthesis of Optically Active Alpha-Halo-Carbonyl Compounds | CHEMINOVA A/S (DK) | 2007-11-29 | — | — | US | disclosed |
| US-20070276142-A1 | Catalytic Asymmetric Synthesis of Optically Active Alpha-Halo-Carbonyl Compounds | CHEMINOVA A/S (DK) | 2007-11-29 | — | — | US | disclosed |
| US-20070276142-A1 | Catalytic Asymmetric Synthesis of Optically Active Alpha-Halo-Carbonyl Compounds | CHEMINOVA A/S (DK) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | ALKBH1, DUT, RNGTT | CYP1A2 4059/4885CYP2D6 888/4885CYP2C19 3230/4885 |
| US-20070276142-A1 | Catalytic Asymmetric Synthesis of Optically Active Alpha-Halo-Carbonyl Compounds | CBR1, CBR3, HAO1 | CYP1A2 55/4885CYP2D6 534/4885CYP2C19 565/4885 |
| US-20180127364-A1 | PYRROLIDINE COMPOUND | CAT, POLI, PPOX | CYP1A2 1239/4885CYP2D6 2099/4885CYP2C19 498/4885 |
| US-20200231620-A1 | TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION | POLRMT, DCLRE1B, RNGTT | CYP1A2 4658/4885CYP2D6 3929/4885CYP2C19 4618/4885 |
| US-20130217901-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 4-CHLORO-3-HYDROXYBUTANAL COMPOUND | ALDH1A2, HPD, ALDH18A1 | CYP1A2 151/4885CYP2D6 115/4885CYP2C19 455/4885 |
| US-20230348524-A1 | TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION | POLRMT, DCLRE1B, RNGTT | CYP1A2 4658/4885CYP2D6 3929/4885CYP2C19 4618/4885 |
| US-10040760-B2 | Pyrrolidine compound | CAT, POLI, PPOX | CYP1A2 1239/4885CYP2D6 2099/4885CYP2C19 498/4885 |
| US-20130137880-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-SUBSTITUTED-3-FORMYL-2-HYDROXYPROPANOIC ACID COMPOUND | HPD, GRHPR, HAAO | CYP1A2 225/4885CYP2D6 229/4885CYP2C19 706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.