Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL29713986 | 1.00 | LMNA (0.32) | LMNATDP1 | |
| SCHEMBL42027 | 0.98 | LMNA (0.35) | LMNATDP1 | |
| Potassium Ion SCHEMBL30372129 | 0.96 | LMNA (0.33) | LMNATDP1 | |
| Potassium Ion SCHEMBL9929143 | 0.96 | LMNA (0.33) | LMNATDP1 | |
| SCHEMBL2721462 | 0.82 | CYP26B1 (0.34) | LMNATDP1 | |
| SCHEMBL560182 | 0.81 | RXRA (0.30) | — | |
| SCHEMBL15129781 | 0.81 | RXRA (0.30) | — | |
| SCHEMBL20767546 | 0.80 | ALDH1A1 (0.35) | LMNATDP1 | |
| Potassium Ion SCHEMBL3791274 | 0.80 | LMNA (0.31) | LMNATDP1 | |
| SCHEMBL24284312 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9631096-B2 | Dye compositions, methods of preparation, conjugates thereof, and methods of use | CORNELL UNIVERSITY (US) | 2017-04-25 | — | — | US | disclosed |
| US-9110069-B2 | Luminescent compounds | SETA BIOMEDICALS, LLC (US) | 2015-08-18 | — | — | US | disclosed |
| US-20150011731-A1 | DYE COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE | CORNELL UNIVERSITY (US) | 2015-01-08 | — | — | US | disclosed |
| US-20140086844-A1 | LUMINESCENT COMPOUNDS | SETA BIOMEDICALS, LLC (US) | 2014-03-27 | — | — | US | disclosed |
| US-8552027-B2 | Luminescent compounds | SETA BIOMEDICALS, LLC (US) | 2013-10-08 | — | — | US | disclosed |
| WO-2013109859-A1 | DYE COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE | CORNELL UNIVERSITY (US) | 2013-07-25 | — | — | WO | disclosed |
| US-20120035346-A1 | LUMINESCENT COMPOUNDS | SETA BIOMEDICALS, LLC | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140086844-A1 | LUMINESCENT COMPOUNDS | PHOSPHO1, PGLS, PFAS | LMNA 986/4885TDP1 1854/4885 |
| US-20120035346-A1 | LUMINESCENT COMPOUNDS | PHOSPHO1, PGLS, PFAS | LMNA 1037/4885TDP1 2133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.