Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4538748 | 0.77 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL9586122 | 0.72 | FDPS (0.32) | — | |
| SCHEMBL131012 | 0.69 | THRB (0.44) | — | |
| SCHEMBL1572578 | 0.67 | LMNA (0.47) | ALDH1A1 | |
| SCHEMBL1495313 | 0.67 | THRB (0.41) | ALDH1A1 | |
| SCHEMBL125895 | 0.67 | — | — | |
| SCHEMBL10574849 | 0.67 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL28532808 | 0.67 | — | — | |
| SCHEMBL3900511 | 0.65 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL24664648 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276095-A2 | PROCESSES FOR PREPARING ASK1 INHIBITORS | Gilead Sciences, Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| CN-112225699-B | Process for preparing ASK1 inhibitors | 吉利德科学公司 | 2023-11-14 | — | — | CN | disclosed |
| US-20230233569-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-07-27 | — | — | US | disclosed |
| EP-3693366-B1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES INC (US) | 2023-06-28 | — | — | EP | disclosed |
| US-11685749-B2 | C26-linked rapamycin analogs as mTOR inhibitors | Revolution Medicines, Inc. (US) | 2023-06-27 | — | — | US | disclosed |
| US-20230158158-A1 | PYRAZOLO QUINAZOLINE DERIVATIVE COMPOUNDS INDUCING SELECTIVE DEGRADATION OF PLK1 | UPPTHERA (KR) | 2023-05-25 | — | — | US | disclosed |
| US-20230055672-A1 | C40-, C28-, and C-32-Linked Rapamycin Analogs as mTOR Inhibitors | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-02-23 | — | — | US | disclosed |
| US-20230038702-A1 | BRIGHT TARGETABLE RED CA2+ INDICATORS | HOWARD HUGHES MEDICAL INSTITUTE | 2023-02-09 | — | — | US | disclosed |
| US-11364300-B2 | C40-, C28-, and C-32-linked rapamycin analogs as mTOR inhibitors | Revolution Medicines, Inc. (US) | 2022-06-21 | — | — | US | disclosed |
| US-20220135527-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES, INC. | 2022-05-05 | — | — | US | disclosed |
| CN-107108519-A | Process for preparing ASK1 inhibitors | 吉利德科学公司 | 2017-08-29 | — | — | CN | disclosed |
| US-20170233350-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES, INC. | 2017-08-17 | — | — | US | disclosed |
| US-9586933-B2 | Processes for preparing ASK1 inhibitors | GILEAD SCIENCES, INC. (US) | 2017-03-07 | — | — | US | disclosed |
| US-20160244430-A1 | Processes for preparing ASK1 inhibitors | GILEAD SCIENCES, INC. (US) | 2016-08-25 | — | — | US | disclosed |
| WO-2016106384-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2016-06-30 | — | — | WO | disclosed |
| US-7164029-B2 | Process for the preparation of benzylimidazole derivatives | DIPHARMA S.P.A. (IT) | 2007-01-16 | — | — | US | disclosed |
| EP-1548009-A2 | Process for the preparation of benzylimidazole derivatives and for losartan | Dipharma S.p.A. (IT) | 2005-06-29 | — | — | EP | disclosed |
| US-20050090672-A1 | Process for the preparation of benzylimidazole derivatives | DIPHARMA S.P.A. (IT) | 2005-04-28 | — | — | US | disclosed |
| US-5213608-A | Sulfonylguanidines | BAYER AKTIENGESELLSCHAFT (DE) | 1993-05-25 | — | — | US | disclosed |
| US-5167692-A | Pre- and postemergence | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685749-B2 | C26-linked rapamycin analogs as mTOR inhibitors | MTOR, RICTOR, RPTOR | ALDH1A1 4742/4885 |
| US-20230038702-A1 | BRIGHT TARGETABLE RED CA2+ INDICATORS | ATP2A2, ATP2A3, CACNB2 | ALDH1A1 2321/4885 |
| US-20170233350-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | MAP3K1, MAP3K6, MAP3K7 | ALDH1A1 2697/4885 |
| US-20050090672-A1 | Process for the preparation of benzylimidazole derivatives | REN, AGTR1, AGTR2 | ALDH1A1 822/4885 |
| US-20230233569-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | KRAS, HRAS, MTOR | ALDH1A1 4528/4885 |
| US-11364300-B2 | C40-, C28-, and C-32-linked rapamycin analogs as mTOR inhibitors | MTOR, RICTOR, RPTOR | ALDH1A1 4803/4885 |
| US-20160244430-A1 | Processes for preparing ASK1 inhibitors | MAP3K1, MAP3K6, MAP3K7 | ALDH1A1 2697/4885 |
| US-20220135527-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | MAP3K1, MAP3K6, MAP3K7 | ALDH1A1 2697/4885 |
| US-20230055672-A1 | C40-, C28-, and C-32-Linked Rapamycin Analogs as mTOR Inhibitors | MTOR, RICTOR, RPTOR | ALDH1A1 4803/4885 |
| US-20230158158-A1 | PYRAZOLO QUINAZOLINE DERIVATIVE COMPOUNDS INDUCING SELECTIVE DEGRADATION OF PLK1 | PLK1, BUB1, BUB1B | ALDH1A1 3638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.