Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | P4HB | P07237 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 2/20 | 0.43 |
| ▸ | IL6 | P05231 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28924635 | 1.00 | NFKB1 (0.58) | NFKB1MAOBP4HBABCG2MEN1 | |
| SCHEMBL323188 | 0.84 | NFKB1 (0.53) | NFKB1MAOBP4HBABCG2MEN1 | |
| SCHEMBL16358097 | 0.83 | NFKB1 (0.42) | NFKB1MAOBP4HBABCG2MEN1 | |
| SCHEMBL8230502 | 0.82 | NFKB1 (0.41) | NFKB1MAOBP4HBABCG2MEN1 | |
| SCHEMBL28740456 | 0.82 | NFKB1 (0.41) | NFKB1MAOBP4HBABCG2MEN1 | |
| SCHEMBL7141617 | 0.80 | NFKB1 (0.60) | NFKB1MAOBP4HBABCG2MEN1 | |
| SCHEMBL7141613 | 0.80 | NFKB1 (0.60) | NFKB1MAOBP4HBABCG2MEN1 | |
| SCHEMBL10382469 | 0.80 | ALDH1A1 (0.43) | NFKB1MAOBP4HBABCG2MEN1 | |
| SCHEMBL31348027 | 0.80 | ALDH1A1 (0.43) | NFKB1MAOBP4HBABCG2MEN1 | |
| SCHEMBL1044013 | 0.78 | NFKB1 (0.58) | NFKB1MAOBP4HBABCG2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646371-A2 | ANTIVIRAL COMPOUNDS AND METHODS | Biotron Limited (AU) | 2006-04-19 | — | — | EP | claimed |
| WO-2004112687-A2 | ANTIVIRAL ACYLGUANIDINE COMPOUNDS AND METHODS | BIOTRON LIMITED (AU) | 2004-12-29 | — | — | WO | claimed |
| EP-3247712-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-04-20 | — | — | EP | disclosed |
| US-20210332039-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-28 | — | — | US | disclosed |
| EP-3353173-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH 5-MEMBERED SULFUR CONTAINING HETEROCYCLIC RING SYSTEMS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-07-21 | — | — | EP | disclosed |
| US-10981907-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-04-20 | — | — | US | disclosed |
| EP-3317276-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-12-16 | — | — | EP | disclosed |
| US-10745396-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-18 | — | — | US | disclosed |
| US-10736320-B2 | Pesticidally active polycyclic derivatives with 5-membered sulfur containing heterocyclic ring systems | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-11 | — | — | US | disclosed |
| EP-3656770-A2 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYCLES | Syngenta Participations AG (CH) | 2020-05-27 | — | — | EP | disclosed |
| EP-3286186-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-06 | — | — | EP | disclosed |
| US-7524991-B2 | Organic electroluminescent devices, aminostyrylnaphthalene compounds and synthesis intermediates thereof, and production processes of the same | SONY CORPORATION (JP) | 2009-04-28 | — | — | US | disclosed |
| US-7524991-B2 | Organic electroluminescent devices, aminostyrylnaphthalene compounds and synthesis intermediates thereof, and production processes of the same | SONY CORPORATION (JP) | 2009-04-28 | — | — | US | disclosed |
| US-7402344-B2 | Organic electroluminescent devices and aminostyrylnaphthalene compounds | SONY CORPORATION (JP) | 2008-07-22 | — | — | US | disclosed |
| US-7402344-B2 | Organic electroluminescent devices and aminostyrylnaphthalene compounds | SONY CORPORATION (JP) | 2008-07-22 | — | — | US | disclosed |
| US-20080146586-A1 | DICARBONYL DERIVATIVES AND METHODS OF USE | ABRAXIS BIOSCIENCE (US) | 2008-06-19 | — | — | US | disclosed |
| US-20080146586-A1 | DICARBONYL DERIVATIVES AND METHODS OF USE | ABRAXIS BIOSCIENCE (US) | 2008-06-19 | — | — | US | disclosed |
| US-20080051607-A1 | ORGANIC ELECTROLUMINESCENT DEVICES, AMINOSTYRLNAPHTHALENE COMPOUNDS AND SYNTHESIS INTERMEDIATES THEREOF, AND PRODUCTION PROCESSES OF THE SAME | SONY CORPORATION (JP) | 2008-02-28 | — | — | US | disclosed |
| US-20080051607-A1 | ORGANIC ELECTROLUMINESCENT DEVICES, AMINOSTYRLNAPHTHALENE COMPOUNDS AND SYNTHESIS INTERMEDIATES THEREOF, AND PRODUCTION PROCESSES OF THE SAME | SONY CORPORATION (JP) | 2008-02-28 | — | — | US | disclosed |
| US-7205324-B2 | Inhibitors of IMPDH enzyme | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146586-A1 | DICARBONYL DERIVATIVES AND METHODS OF USE | AADAC, DCK, MLYCD | NFKB1 1269/4885MAOB 2670/4885P4HB 1352/4885 |
| US-20080051607-A1 | ORGANIC ELECTROLUMINESCENT DEVICES, AMINOSTYRLNAPHTHALENE COMPOUNDS AND SYNTHESIS INTERMEDIATES THEREOF, AND PRODUCTION PROCESSES OF THE SAME | ASNS, RPS24, L1CAM | NFKB1 3321/4885MAOB 799/4885P4HB 3302/4885 |
| US-10981907-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | DDT, ACHE, GSTM1 | NFKB1 1850/4885MAOB 738/4885P4HB 664/4885 |
| US-10745396-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | DDT, SQOR, ACHE | NFKB1 2328/4885MAOB 527/4885P4HB 517/4885 |
| US-20210332039-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, ACHE, SQOR | NFKB1 1697/4885MAOB 841/4885P4HB 644/4885 |
| US-10736320-B2 | Pesticidally active polycyclic derivatives with 5-membered sulfur containing heterocyclic ring systems | DDT, TST, GSS | NFKB1 1027/4885MAOB 1072/4885P4HB 709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.